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anti-CD134 antibody :: Rat CD134 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS210684
Unit / Price
0.1 mg  /  $210 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD134, Monoclonal Antibody

★Popular Item★
 Also Known As   

RAT ANTI MOUSE CD134:FITC

 Product Gene Name   

anti-CD134 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P47741
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    OX-86
 Host    Rat
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 Form/Format    FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
 Concentration    IgG concentration 0.1 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide
1% Bovine Serum Albumin
Preparation
 Immunogen    CHO cells transfected with murine OX40
Fusion Partners
 Target Species    Mouse
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 Preparation and Storage    Store at 4 degree C for one month or at -20 degree C for longer. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD134 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD134 antibody

   Rat anti Mouse CD134 antibody, clone OX-86 recognizes murine OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes. Rat anti Mouse CD134 antibody, clone OX-86 is routinely tested on concanavalin A activated mouse splenocytes.
 Applications Tested/Suitable for anti-CD134 antibody   

Flow cytometry (FC/FACS)

 Application Notes for anti-CD134 antibody    Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
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 Testing Data of anti-CD134 antibody    Staining of stimulated rat spleen cells with Rat anti Mouse CD134:Azide Free (MBS210149)
anti-CD134 antibody Testing Data image
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 Testing Data of anti-CD134 antibody    Staining of Concanavalin A stimulated mouse spleen cells with Rat anti Mouse CD134:Alexa Fluor 647 (MBS212139A647)
anti-CD134 antibody Testing Data image
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 Testing Data of anti-CD134 antibody    Staining of Concanavalin A stimulated mouse spleen cells with Rat anti Mouse CD134:RPE (MBS213601)
anti-CD134 antibody Testing Data image
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 Testing Data of anti-CD134 antibody    Staining of Concanavalin A stimulated mouse spleen cells with Rat anti Mouse CD134 (MBS212139)
anti-CD134 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CD134. It may not necessarily be applicable to this product.
 NCBI GI #    6755909
 NCBI GeneID    22163
 NCBI Accession #    NP_035789.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011659.2 [Other Products]
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 UniProt Primary Accession #    P47741 [Other Products]
 UniProt Related Accession #    P47741 [Other Products]
 Molecular Weight    30,154 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 4
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 4
 NCBI Official Symbol    Tnfrsf4 [Similar Products]
 NCBI Official Synonym Symbols   
Ox40; ACT35; CD134; Ly-70; Txgp1; TXGP1L
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 4; OX40 antigen; OX40L receptor; tax-transcriptionally activated glycoprotein 1
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 4
 UniProt Synonym Protein Names   
OX40 antigen; OX40L receptor; CD_antigen: CD134
 UniProt Gene Name    Tnfrsf4 [Similar Products]
 UniProt Synonym Gene Names    Ox40; Txgp1 [Similar Products]
 UniProt Entry Name    TNR4_MOUSE
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 UniProt Comments for CD134    TNFRSF4: Receptor for TNFSF4/OX40L/GP34.

Protein type: Receptor, misc.; Apoptosis; Membrane protein, integral

Cellular Component: cell surface; membrane; plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; tumor necrosis factor receptor activity

Biological Process: regulation of apoptosis; T cell proliferation; tumor necrosis factor-mediated signaling pathway; negative regulation of transcription factor activity; negative regulation of cytokine secretion; positive regulation of B cell proliferation; programmed cell death; cellular defense response; positive regulation of immunoglobulin secretion; inflammatory response; regulation of protein kinase activity; negative regulation of transcription, DNA-dependent
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 Research Articles on CD134    1. OX40 was highly expressed by intratumoral T cells, particularly those of the FoxP3(+) regulatory T-cell (Treg) lineage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CD134 antibodyDiseases associated with anti-CD134 antibody
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >295 publications with CD134 and Necrosis
 Immune System Diseases Antibodies  >123 publications with CD134 and Immune System Diseases
 Disease Models, Animal Antibodies  >58 publications with CD134 and Disease Models, Animal
 Autoimmune Diseases Antibodies  >58 publications with CD134 and Autoimmune Diseases
 Inflammation Antibodies  >50 publications with CD134 and Inflammation
 Lung Diseases Antibodies  >23 publications with CD134 and Lung Diseases
 Nervous System Diseases Antibodies  >23 publications with CD134 and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >23 publications with CD134 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >21 publications with CD134 and Cardiovascular Diseases
 Brain Diseases Antibodies  >14 publications with CD134 and Brain Diseases
Organs/Tissues associated with anti-CD134 antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >23 publications with CD134 and Lung
 Skin Antibodies  >23 publications with CD134 and Skin
 Bone Antibodies  >16 publications with CD134 and Bone
 Bone Marrow Antibodies  >15 publications with CD134 and Bone Marrow
 Mixed Antibodies  >8 publications with CD134 and Mixed
 Thymus Antibodies  >4 publications with CD134 and Thymus
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