View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-CD152 antibody :: Mouse anti-Rat CD152 Monoclonal Antibody Catalog # MBS520058 Unit / Price 0.1 mg / $340 +1 FREE 8GB USB 0.5 mg / $735 +1 FREE 8GB USB 5x0.5 mg / $3,030 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CD152, Monoclonal Antibody Full Product Name Anti-Rat CD152 FITC (Clone WKH 203) (mouse IgG1) Product Synonym Names CD152 FITC (Clone WKH 203) (mouse IgG1); FITC Anti-Rat CD152 (CTLA-4) Monoclonal Antibody Product Gene Name anti-CD152 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype mouse IgG1 Clone Number WKH 203 Host Mouse Species Reactivity Rat Specificity CD152 (CTLA-4) (Rat CD152) Form/Format FITC (FITC conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography).) Concentration Antibody Concentration: 0.1 mg/ml (lot specific) Immunogen Purified rCTLA-4hlg fusion protein Donor BALB/c mice spleen cells Fusion Partner X63 Ag8.653 myeloma cells Presentation 100 ug or 500 ug FITC conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. Preparation and Storage Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles. Avoid prolonged exposure to light. Other Notes Small volumes of anti-CD152 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-CD152 antibody anti-rat CD152 monoclonal antibody is specific for the cytotoxic T lymphocyteassociated protein 4 (CTLA-4), also called CD152. This antigen is known to be the receptor for B7 ligands (CD80 and CD86) present on antigen presenting cells. A subset of CD4 T cells expressing CD25 and CTLA-4 has been recognized as a potent suppressor cell population, counteracting autoimmunity and inflammation. These 'regulatory' T cells (Treg) which produce the anti-inflammatory cytokine interleukin-10 (IL-10) but not IL-2, are able to suppress the proliferation of costimulated CD25- negative indicator cells. The capacity of these naturally occurring regulatory T cells to suppress autoimmunity and inflammation suggests that therapies which activate and expand this subset could become extremely effective treatments for these immunopathological disorders. This clone has been tested in flow cytometry. In rats, the constitutive expression of CTLA-4 at the level detectable by flow cytometry is restricted to the CD25+ subset of CD4 T cells and thymocytes. Applications Tested/Suitable for anti-CD152 antibody Immunohistochemistry (IHC) TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP