Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CD16/CD32 rightarrow Monoclonal CD16/CD32  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • sideroflexin 4 (SFXN4) ELISA Kit
 • E. coli (O & K antigens) Antibody
 • 24-methylenesterol C-methyltransferase 3 (SMT3) Recombinant Protein
 • hCG beta Antibody
 • Hepatitis C Virus Nucleocapsid (HCV) Recombinant Protein
 • Ataxin 2 (ATXN2) ELISA Kit
 • Cluster of Differentiation 226 (CD226) ELISA Kit
 • Adiponectin (ADP) ELISA Kit
 • Receptor III For The Fc Region of Immunoglobulin G (FcGRIII) ELISA Kit
 • Integrin beta 3 (ITGB3) Antibody
 • Interleukin 4 (IL4) ELISA Kit
 • GAPDH mAb Antibody
 • IkBa (NFKB1A) (IkBa (NFKB1A)) Antibody
 • Proteasome subunit beta type-9 (LMP2 - PSMB9) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CD16/CD32 antibody :: Rat CD16/CD32 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS210943
Unit / Price
0.1 mg  /  $210 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD16/CD32, Monoclonal Antibody

★Popular Item★
 Also Known As   

RAT ANTI MOUSE CD16/CD32:FITC

 Product Gene Name   

anti-CD16/CD32 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    FCR4G8
 Host    Rat
Section Bar
 Form/Format    FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
 Concentration    IgG concentration 0.1 mg/ml (lot specific)
Section Bar
 Perservative Stabilisers    0.09% Sodium Azide
1% Bovine Serum Albumin
Preparation
 Immunogen    PU5 1.8 IOE7 Balb/c mouse cell line.
Fusion Partners
 Target Species    Mouse
Section Bar
 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD16/CD32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-CD16/CD32 antibody

   Rat anti Mouse CD16/CD32 antibody, clone FCR4G8 recognizes an epitope expressed by the murine low affinity Fc receptors, Fc gamma III (CD16) and Fc gamma II (CD32). In the mouse only the transmembrane form of CD16 is reported to exist, which is expressed on macrophages, NK cells, granulocytes, myeloid precursors, and subpopulations of T lymphocytes. CD32 is primarily expressed on cells of the myeloid lineage and also on mature B lymphocytes.
 Applications Tested/Suitable for anti-CD16/CD32 antibody   

Flow cytometry (FC/FACS)

 Application Notes for anti-CD16/CD32 antibody    Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
Section Bar
 Testing Data of anti-CD16/CD32 antibody    Staining of mouse peripheral blood lymphocytes Rat anti Mouse CD16/32: Alexa Fluor 488 (MBS212682A488)
anti-CD16/CD32 antibody Testing Data image
Section Bar
 Testing Data of anti-CD16/CD32 antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD16/32 : RPE (MBS213784)
anti-CD16/CD32 antibody Testing Data image
Section Bar
 Testing Data of anti-CD16/CD32 antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD16/32: FITC
anti-CD16/CD32 antibody Testing Data image
Section Bar
 Testing Data of anti-CD16/CD32 antibody    Staining of mouse peripheral blood granulocytes with Rat anti Mouse CD16/32: Biotin (MBS210447)
anti-CD16/CD32 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD16/CD32. It may not necessarily be applicable to this product.
 NCBI GI #    6857783
 NCBI GeneID    14130
 NCBI Accession #    NP_034317.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_010187.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    P08102; P12316; P97917; Q60938; Q60939; Q60940; Q61170; Q61558 [Other Products]
 UniProt Related Accession #    P08101 [Other Products]
 Molecular Weight    – Da
Table BarTOPTable Bar
 NCBI Official Full Name    low affinity immunoglobulin gamma Fc region receptor II-b isoform 2
 NCBI Official Synonym Full Names    Fc receptor, IgG, low affinity IIb
 NCBI Official Symbol    Fcgr2b [Similar Products]
 NCBI Official Synonym Symbols   
CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik
[Similar Products]
 NCBI Protein Information    low affinity immunoglobulin gamma Fc region receptor II-b; Fc gamma RIIB; Fc-gamma-RII; FcgammaRIIB; fc gamma receptor IIB; fc-gamma RII; fc-gamma-RIIB; igG Fc receptor II beta; lymphocyte antigen 17
 UniProt Protein Name    Low affinity immunoglobulin gamma Fc region receptor II
 UniProt Synonym Protein Names   
Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII; IgG Fc receptor II beta; Lymphocyte antigen 17; Ly-17; CD_antigen: CD32
 UniProt Gene Name    Fcgr2 [Similar Products]
 UniProt Synonym Gene Names    Fcgr2b; Ly-17; Fc-gamma RII; Fc-gamma-RIIB; FcRII; Ly-17 [Similar Products]
 UniProt Entry Name    FCGR2_MOUSE
Section Bar
 UniProt Comments for CD16/CD32    FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.

Protein type: Membrane protein, integral; Oncoprotein; Cell surface

Cellular Component: recycling endosome; cell surface; cytoskeleton; membrane; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region; integral to membrane; lipid raft; external side of plasma membrane

Molecular Function: protein binding; IgG binding; receptor signaling protein activity; immunoglobulin binding

Biological Process: receptor-mediated endocytosis; negative regulation of phagocytosis; negative regulation of interleukin-10 production; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; defense response; negative regulation of B cell proliferation; endocytic recycling; negative regulation of type I hypersensitivity; mast cell activation; negative regulation of neutrophil apoptosis; negative regulation of humoral immune response mediated by circulating immunoglobulin; cell surface receptor linked signal transduction; response to bacterium; positive regulation of phagocytosis; negative regulation of immunoglobulin production; immune complex clearance; negative regulation of inflammatory response to antigenic stimulus; immune response; immunoglobulin mediated immune response; phagocytosis, engulfment
Table BarTOPTable Bar
 Research Articles on CD16/CD32    1. 12-LOX has an essential role in regulating FcgammaRIIa-mediated platelet function
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CD16/CD32 antibodyPathways associated with anti-CD16/CD32 antibody
 Reference Product  PubMed Publications
 Lyn antibody  >2 publications with CD16/CD32 and Lyn
 Lpl antibody  >2 publications with CD16/CD32 and Lpl
 Lilrb3 antibody  >1 publications with CD16/CD32 and Lilrb3
 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram
Diseases associated with anti-CD16/CD32 antibodyOrgans/Tissues associated with anti-CD16/CD32 antibody
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >130 publications with CD16/CD32 and Autoimmune Diseases
 Lupus Erythematosus, Systemic Antibodies  >67 publications with CD16/CD32 and Lupus Erythematosus, Systemic
 Inflammation Antibodies  >47 publications with CD16/CD32 and Inflammation
 Disease Models, Animal Antibodies  >44 publications with CD16/CD32 and Disease Models, Animal
 Kidney Diseases Antibodies  >26 publications with CD16/CD32 and Kidney Diseases
 Necrosis Antibodies  >17 publications with CD16/CD32 and Necrosis
 Nervous System Diseases Antibodies  >17 publications with CD16/CD32 and Nervous System Diseases
 Lung Diseases Antibodies  >14 publications with CD16/CD32 and Lung Diseases
 Anemia Antibodies  >6 publications with CD16/CD32 and Anemia
 Malaria Antibodies  >5 publications with CD16/CD32 and Malaria
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >185 publications with CD16/CD32 and Blood
 Spleen Antibodies  >28 publications with CD16/CD32 and Spleen
 Bone Antibodies  >21 publications with CD16/CD32 and Bone
 Bone Marrow Antibodies  >19 publications with CD16/CD32 and Bone Marrow
 Lung Antibodies  >8 publications with CD16/CD32 and Lung
 Artery Antibodies  >8 publications with CD16/CD32 and Artery
 Liver Antibodies  >5 publications with CD16/CD32 and Liver
 Thymus Antibodies  >3 publications with CD16/CD32 and Thymus
 Skin Antibodies  >3 publications with CD16/CD32 and Skin
 Embryonic Tissue Antibodies  >2 publications with CD16/CD32 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions