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anti-CD19 antibody :: Mouse anti-Human CD19 CD19 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS530888 anti-CD19 antibody
Unit / Price
0.5 mg  /  $570 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD19, Monoclonal Antibody

★Popular Item★
 Also Known As   

CD19 antibody (Azide Free)

 Product Synonym Names    Monoclonal CD19; Anti-CD19; CD 19; CD-19; CD19
 Product Gene Name   

anti-CD19 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    107265
 3D Structure    ModBase 3D Structure for P15391
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    SJ25-C1
 Host    Mouse
 Species Reactivity    Human CD19
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 Form/Format    Liquid in PBS, pH 7.4
 Concentration    0.5 mg/ml (lot specific)
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 Biological Significance    B-lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene.
 Immunogen    CD19 antibody (Azide free) was raised in mouse using human CD19 as the immunogen.
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 Preparation and Storage    Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles
 Other Notes    Small volumes of anti-CD19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CD19 antibody

   Mouse monoclonal CD19 antibody (Azide Free)
 Product Categories/Family for anti-CD19 antibody    Immunology
 Applications Tested/Suitable for anti-CD19 antibody   

Flow Cytometry (FC/FACS), Immunohistochemistry-Frozen (IHC-F), Immunoprecipitation (IP)

 Application Notes for anti-CD19 antibody    Endotoxin Level: < = 6.25 EU/ml at 0.5mg/ml as determined by LAL.
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NCBI/Uniprot data below describe general gene information for CD19. It may not necessarily be applicable to this product.
 NCBI GI #    91105174
 NCBI GeneID    930
 NCBI Accession #    NP_001761.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001770.5 [Other Products]
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 UniProt Primary Accession #    P15391 [Other Products]
 UniProt Secondary Accession #    Q96S68; Q9BRD6; A0N0P9; F5H635 [Other Products]
 UniProt Related Accession #    P15391 [Other Products]
 Molecular Weight    61,200 Da
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 NCBI Official Full Name    B-lymphocyte antigen CD19 isoform 2
 NCBI Official Synonym Full Names    CD19 molecule
 NCBI Official Symbol    CD19 [Similar Products]
 NCBI Official Synonym Symbols   
B4; CVID3
[Similar Products]
 NCBI Protein Information    B-lymphocyte antigen CD19
 UniProt Protein Name    B-lymphocyte antigen CD19
 UniProt Synonym Protein Names   
B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen: CD19
 Protein Family    B-lymphocyte antigen
 UniProt Gene Name    CD19 [Similar Products]
 UniProt Entry Name    CD19_HUMAN
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 NCBI Summary for CD19    Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD19    CD19: a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signaling. Germinal center formation is significantly reduced in CD19-deficient mice.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: protein complex; integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: receptor signaling protein activity

Biological Process: epidermal growth factor receptor signaling pathway; B cell receptor signaling pathway; regulation of immune response; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; cell surface receptor linked signal transduction; nerve growth factor receptor signaling pathway; innate immune response; cellular defense response; positive regulation of release of sequestered calcium ion into cytosol

Disease: Immunodeficiency, Common Variable, 2; Immunodeficiency, Common Variable, 3
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 Research Articles on CD19    1. propose a multilayer model of plasma cell (PC) memory in which CD19(+) and CD19(-) PC represent dynamic and static components, respectively, permitting both adaptation and stability of humoral immune protection
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD19 antibodyPathways associated with anti-CD19 antibody
 Reference Product  PubMed Publications
 CD22 antibody  >614 publications with CD19 and CD22
 CD79A antibody  >152 publications with CD19 and CD79A
 CD79B antibody  >109 publications with CD19 and CD79B
 CD81 antibody  >102 publications with CD19 and CD81
 CR2 antibody  >76 publications with CD19 and CR2
 LYN antibody  >59 publications with CD19 and LYN
 SYK antibody  >49 publications with CD19 and SYK
 VAV1 antibody  >13 publications with CD19 and VAV1
 PIK3R1 antibody  >2 publications with CD19 and PIK3R1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies  Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 Constitutive Signaling By Aberrant PI3K In Cancer Pathway antibodies  Constitutive Signaling By Aberrant PI3K In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
Diseases associated with anti-CD19 antibodyOrgans/Tissues associated with anti-CD19 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >459 publications with CD19 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >433 publications with CD19 and Vascular Diseases
 Inflammation Antibodies  >378 publications with CD19 and Inflammation
 Necrosis Antibodies  >339 publications with CD19 and Necrosis
 Neoplasms, Experimental Antibodies  >326 publications with CD19 and Neoplasms, Experimental
 Death Antibodies  >274 publications with CD19 and Death
 Lung Diseases Antibodies  >217 publications with CD19 and Lung Diseases
 Liver Diseases Antibodies  >171 publications with CD19 and Liver Diseases
 Common Variable Immunodeficiency Antibodies  >93 publications with CD19 and Common Variable Immunodeficiency
 Agammaglobulinemia Antibodies  >89 publications with CD19 and Agammaglobulinemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6409 publications with CD19 and Blood
 Bone Marrow Antibodies  >1781 publications with CD19 and Bone Marrow
 Spleen Antibodies  >590 publications with CD19 and Spleen
 Lymph Node Antibodies  >483 publications with CD19 and Lymph Node
 Lymph Antibodies  >433 publications with CD19 and Lymph
 Lung Antibodies  >218 publications with CD19 and Lung
 Thymus Antibodies  >175 publications with CD19 and Thymus
 Brain Antibodies  >143 publications with CD19 and Brain
 Tonsil Antibodies  >119 publications with CD19 and Tonsil
 Intestine Antibodies  >107 publications with CD19 and Intestine
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