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anti-CD2 antibody :: Rabbit CD2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS303405
Unit / Price
  DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD2, Monoclonal Antibody

 Also Known As   

CD2

 Product Gene Name   

anti-CD2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M19806
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 Clonality    Monoclonal
 Isotype    IgG
 Clone Number    SP304
 Host    Rabbit
 Species Reactivity    Tested Reactivity: Human
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 Cellular Localization    Membrane
 Control Tissue    Tonsil
 Immunogen    Recombinant human CD2 protein.
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 Preparation and Storage    Store at 2-8 degree C
 Other Notes    Small volumes of anti-CD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD2 antibody

   T-cell surface antigen CD2 is a calcium-independent cell adhesion glycoprotein normally expressed on T cells, NK cells, thymocytes, and T-cell lymphomas. It interacts with CD58 (LFA-3) on the surface of antigen presented cells and contributes to T-cell activation.
 Applications Tested/Suitable for anti-CD2 antibody   

Immunohistochemistry (IHC) Paraffin

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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604 (CD2) Tonsil
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-1 (CD2) Tonsil
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-2 (CD2) Thymus
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-3 (CD2) Colon
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-4 (CD2) Stomach
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-5 (CD2) Stomach Adenocarcinoma
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-6 (CD2) Colon Adenocarcinoma
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-7 (CD2) Lung Squamous Cell Carcinoma
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CD2 antibody    M604-8 (CD2) Lung Adenocarcinoma
anti-CD2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CD2. It may not necessarily be applicable to this product.
 NCBI GI #    958931301
 NCBI GeneID    914
 NCBI Accession #    JAO98287.1 [Other Products]
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 UniProt Secondary Accession #    Q96TE5 [Other Products]
 UniProt Related Accession #    P06729 [Other Products]
 Molecular Weight    39 kDa
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 NCBI Official Full Name    CD2, partial
 NCBI Official Synonym Full Names    CD2 molecule
 NCBI Official Symbol    CD2 [Similar Products]
 NCBI Official Synonym Symbols   
T11; SRBC; LFA-2
[Similar Products]
 NCBI Protein Information    T-cell surface antigen CD2
 UniProt Protein Name    T-cell surface antigen CD2
 UniProt Synonym Protein Names   
Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2
 Protein Family    CD2
 UniProt Gene Name    CD2 [Similar Products]
 UniProt Synonym Gene Names    SRBC [Similar Products]
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 NCBI Summary for CD2    The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
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 UniProt Comments for CD2    CD2: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.

Protein type: Apoptosis; Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: cell surface; external side of plasma membrane; plasma membrane

Molecular Function: protein binding; receptor binding

Biological Process: apoptosis; cell surface receptor linked signal transduction; heterotypic cell-cell adhesion; leukocyte migration; lipid raft polarization; positive regulation of tumor necrosis factor production; T cell activation
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 Research Articles on CD2    1. Establish CD2 as a new susceptibility factor for systemic sclerosis in a European Caucasian population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD2 antibodyPathways associated with anti-CD2 antibody
 Reference Product  PubMed Publications
 CD58 antibody  >426 publications with CD2 and CD58
 CD2AP antibody  >189 publications with CD2 and CD2AP
 CD48 antibody  >148 publications with CD2 and CD48
 LCK antibody  >80 publications with CD2 and LCK
 SH3KBP1 antibody  >19 publications with CD2 and SH3KBP1
 CD2BP2 antibody  >14 publications with CD2 and CD2BP2
 SYK antibody  >12 publications with CD2 and SYK
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-CD2 antibodyOrgans/Tissues associated with anti-CD2 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >321 publications with CD2 and Necrosis
 Inflammation Antibodies  >259 publications with CD2 and Inflammation
 Chromosome Aberrations Antibodies  >181 publications with CD2 and Chromosome Aberrations
 Kidney Diseases Antibodies  >166 publications with CD2 and Kidney Diseases
 Skin Neoplasms Antibodies  >137 publications with CD2 and Skin Neoplasms
 Liver Diseases Antibodies  >134 publications with CD2 and Liver Diseases
 Vascular Diseases Antibodies  >111 publications with CD2 and Vascular Diseases
 Lung Diseases Antibodies  >111 publications with CD2 and Lung Diseases
 Cell Transformation, Neoplastic Antibodies  >98 publications with CD2 and Cell Transformation, Neoplastic
 Proteinuria Antibodies  >92 publications with CD2 and Proteinuria
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4789 publications with CD2 and Blood
 Bone Antibodies  >808 publications with CD2 and Bone
 Muscle Antibodies  >553 publications with CD2 and Muscle
 Kidney Antibodies  >521 publications with CD2 and Kidney
 Thymus Antibodies  >442 publications with CD2 and Thymus
 Lymph Node Antibodies  >407 publications with CD2 and Lymph Node
 Heart Antibodies  >318 publications with CD2 and Heart
 Spleen Antibodies  >291 publications with CD2 and Spleen
 Intestine Antibodies  >259 publications with CD2 and Intestine
 Lung Antibodies  >196 publications with CD2 and Lung
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