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anti-CD2 antibody :: Mouse anti-Rat CD2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS520064
Testing Data
Unit / Price
0.1 mg  /  $250 +1 FREE 8GB USB
0.5 mg  /  $420 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD2, Monoclonal Antibody

★Popular Item★
 Also Known As   

Anti-Rat CD2 Biotin (Clone OX-34) (mouse IgG2a)

 Product Synonym Names    CD2 Biotin (Clone OX-34) (mouse IgG2a); Anti-Rat CD2 (LFA-2) Monoclonal Antibody
 Product Gene Name   

anti-CD2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (117297057..117311851). Location: 1p13.1
 OMIM    186990
 3D Structure    ModBase 3D Structure for P06729
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 Clonality    Monoclonal
 Isotype    Mouse IgG2a
 Clone Number    OX-34
 Host    Mouse
 Species Reactivity    Rat
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 Specificity    CD2 (LFA-2) (Rat CD2 (LFA-2))
 Form/Format    Biotin
 Concentration    0.1 mg/ml (lot specific)
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 Immunogen    T Blasts prepared in mixed lymphocyte reactions with rat T helper cells against irradiated spleen
 Donor    BALB/c spleen
 Fusion Partner    NSO/1
 Presentation    Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
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 Preparation and Storage    For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin, FITC, No Azide), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles
 Other Notes    Small volumes of anti-CD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD2 antibody

   biotin anti-rat CD2 (LFA-2) monoclonal antibody reacts with the 50 kDa surface glycoprotein LFA-2, designated as CD2. LFA-2 is the receptor for LFA-3. This antibody labels all peripheral T cells and most thymocytes but does not label B cells or peritoneal macrophages. It does not activate T cells (1,2,3). This clone is reported to work with frozen and paraffin sections (4).
 Applications Tested/Suitable for anti-CD2 antibody   

Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

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 Testing Data of anti-CD2 antibody    anti-CD2 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CD2. It may not necessarily be applicable to this product.
 NCBI GI #    156071472
 NCBI GeneID    914
 NCBI Accession #    NP_001758.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001767.3 [Other Products]
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 UniProt Primary Accession #    P06729 [Other Products]
 UniProt Secondary Accession #    Q96TE5 [Other Products]
 UniProt Related Accession #    P06729 [Other Products]
 Molecular Weight    39,448 Da
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 NCBI Official Full Name    T-cell surface antigen CD2
 NCBI Official Synonym Full Names    CD2 molecule
 NCBI Official Symbol    CD2 [Similar Products]
 NCBI Official Synonym Symbols   
T11; SRBC; LFA-2
[Similar Products]
 NCBI Protein Information    T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
 UniProt Protein Name    T-cell surface antigen CD2
 UniProt Synonym Protein Names   
Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5
 Protein Family    CD2
 UniProt Gene Name    CD2 [Similar Products]
 UniProt Synonym Gene Names    SRBC [Similar Products]
 UniProt Entry Name    CD2_HUMAN
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 NCBI Summary for CD2    CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
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 UniProt Comments for CD2    Function: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Subunit structure: Interacts with CD2AP

By similarity. Interacts with PSTPIP1. Ref.11

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
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 Research Articles on CD2    1. Altogether, these results show that a high CD2 expression level is a hallmark of latently infected resting memory CD4(+) T cells in vivo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CD2 antibodyDiseases associated with anti-CD2 antibody
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Disease Name  Pubmed Publications
 Lymphoma Antibodies  >827 publications with CD2 and Lymphoma
 Necrosis Antibodies  >307 publications with CD2 and Necrosis
 Lymphoma, B-Cell Antibodies  >235 publications with CD2 and Lymphoma, B-Cell
 Inflammation Antibodies  >225 publications with CD2 and Inflammation
 Kidney Diseases Antibodies  >143 publications with CD2 and Kidney Diseases
 Liver Diseases Antibodies  >123 publications with CD2 and Liver Diseases
 Anemia Antibodies  >99 publications with CD2 and Anemia
 Vascular Diseases Antibodies  >97 publications with CD2 and Vascular Diseases
 Fever Antibodies  >97 publications with CD2 and Fever
 Arthritis, Rheumatoid Antibodies  >82 publications with CD2 and Arthritis, Rheumatoid
Organs/Tissues associated with anti-CD2 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4605 publications with CD2 and Blood
 Bone Antibodies  >751 publications with CD2 and Bone
 Muscle Antibodies  >540 publications with CD2 and Muscle
 Kidney Antibodies  >473 publications with CD2 and Kidney
 Thymus Antibodies  >436 publications with CD2 and Thymus
 Lymph Node Antibodies  >381 publications with CD2 and Lymph Node
 Heart Antibodies  >303 publications with CD2 and Heart
 Spleen Antibodies  >271 publications with CD2 and Spleen
 Intestine Antibodies  >250 publications with CD2 and Intestine
 Lung Antibodies  >179 publications with CD2 and Lung
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