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anti-CD200R antibody :: Rat CD200R Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211221
Unit / Price
0.5 mg  /  $540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD200R, Monoclonal Antibody

 Also Known As   

RAT ANTI MOUSE CD200R:Low Endotoxin

 Product Gene Name   

anti-CD200R antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9ES57
 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    OX-110
 Host    Rat
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 Form/Format    Low Endotoxin
Purified IgG - liquid
 Concentration    IgG concentration 1.0 mg/ml (lot specific)
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 Preparation    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
 Buffer Solution    Phosphate buffered saline
 Target Species    Mouse
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 Preparation and Storage    Store at -20 degree C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD200R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CD200R antibody

   Rat anti Mouse CD200R antibody, clone OX-110 recognizes mouse CD200R, a cell surface glycoprotein (also known as OX2R. Mouse CD200R is a 326 amino acid, ~48kDa single pass type I transmembrane glycoprotein, expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (Wright et al.2003). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function (Minas and Liversidge 2006). Rat anti Mouse CD200R antibody, clone OX-110 has been used successfully for the immunohistochemical detection of CD200R expressing cells on acetone fixed cryosections of murine synovial tissue (Simelyte et al. 2008).
 Applications Tested/Suitable for anti-CD200R antibody   

Flow cytometry (FC/FACS)

 Application Notes for anti-CD200R antibody    Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul
Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/50
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 Testing Data of anti-CD200R antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD200R (MBS212645)
anti-CD200R antibody Testing Data image
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 Testing Data of anti-CD200R antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD200R: FITC (MBS210911)
anti-CD200R antibody Testing Data image
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 Testing Data of anti-CD200R antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD200R (MBS212646)
anti-CD200R antibody Testing Data image
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 Testing Data of anti-CD200R antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD200R: Alexa Fluor 488 (MBS212645A488)
anti-CD200R antibody Testing Data image
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 Testing Data of anti-CD200R antibody    Staining of mouse peripheral blood granulocytes with Rat anti Mouse CD200R: RPE (MBS213768)
anti-CD200R antibody Testing Data image
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 Testing Data of anti-CD200R antibody    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD200R: Low Endotoxin
anti-CD200R antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CD200R. It may not necessarily be applicable to this product.
 NCBI GI #    10946634
 NCBI GeneID    57781
 NCBI Accession #    NP_067300.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021325.3 [Other Products]
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 UniProt Primary Accession #    Q9ES57 [Other Products]
 UniProt Related Accession #    Q9ES57 [Other Products]
 Molecular Weight    35,505 Da
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 NCBI Official Full Name    cell surface glycoprotein CD200 receptor 1
 NCBI Official Synonym Full Names    CD200 receptor 1
 NCBI Official Symbol    Cd200r1 [Similar Products]
 NCBI Official Synonym Symbols   
OX2R; Mox2r; CD200R
[Similar Products]
 NCBI Protein Information    cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Orexin receptor 2; antigen identified by monoclonal antibody MRC OX-2 receptor; cell surface glycoprotein OX2 receptor 1
 UniProt Protein Name    Cell surface glycoprotein CD200 receptor 1
 UniProt Synonym Protein Names   
CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1
 UniProt Gene Name    Cd200r1 [Similar Products]
 UniProt Synonym Gene Names    Mox2r; Ox2r [Similar Products]
 UniProt Entry Name    MO2R1_MOUSE
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 UniProt Comments for CD200R    CD200R: Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. Belongs to the CD200R family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: membrane; plasma membrane; integral to membrane; receptor complex; external side of plasma membrane

Molecular Function: protein binding; receptor activity
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 Research Articles on CD200R    1. CD200-CD200R1 interaction in glial cells is involved in the neuroprotective action of PPAR-gamma agonists.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD200R antibodyPathways associated with anti-CD200R antibody
 Reference Product  PubMed Publications
 Cd200 antibody  >78 publications with CD200R and Cd200
 Cd200r2 antibody  >6 publications with CD200R and Cd200r2
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Diseases associated with anti-CD200R antibodyOrgans/Tissues associated with anti-CD200R antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >22 publications with CD200R and Inflammation
 Necrosis Antibodies  >9 publications with CD200R and Necrosis
 Disease Models, Animal Antibodies  >6 publications with CD200R and Disease Models, Animal
 Carcinoma Antibodies  >6 publications with CD200R and Carcinoma
 Respiratory Tract Diseases Antibodies  >5 publications with CD200R and Respiratory Tract Diseases
 Lupus Erythematosus, Systemic Antibodies  >3 publications with CD200R and Lupus Erythematosus, Systemic
 Respiratory Tract Infections Antibodies  >3 publications with CD200R and Respiratory Tract Infections
 Skin Neoplasms Antibodies  >3 publications with CD200R and Skin Neoplasms
 Fibrosis Antibodies  >2 publications with CD200R and Fibrosis
 Lung Diseases Antibodies  >2 publications with CD200R and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >46 publications with CD200R and Blood
 Skin Antibodies  >15 publications with CD200R and Skin
 Bone Marrow Antibodies  >8 publications with CD200R and Bone Marrow
 Embryonic Tissue Antibodies  >3 publications with CD200R and Embryonic Tissue
 Thymus Antibodies  >2 publications with CD200R and Thymus
 Liver Antibodies  >2 publications with CD200R and Liver
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