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anti-CD248 antibody :: Mouse anti-Human CD248 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2542325
Western Blot (WB)
Unit / Price
0.06 mL  /  $220 +1 FREE 8GB USB
0.12 mL  /  $290 +1 FREE 8GB USB
0.2 mL  /  $435 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD248, Monoclonal Antibody

 Also Known As   

CD248 Monoclonal Antibody

 Product Synonym Names    CD164 sialomucin like 1; CD164L1; CD248; CD248 antigen endosialin; CD248 molecule endosialin; CD248; Endosialin; TEM 1; TEM1; Tumor endothelial marker 1
 Product Gene Name   

anti-CD248 antibody

[Similar Products]
 Product Synonym Gene Name    TEM1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    More" target="_blank" rel="nofollow">606064 gene
 3D Structure    ModBase 3D Structure for Q9HCU0
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    460
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Caprylic acid/ammonium sulfate precipitation
 Concentration    1mg/mL (lot specific)
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 Immunogen    Fusion protein of TEM1
 Buffer    PBS with 0.1% sodium azide, 50% glycerol, PH7.3
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CD248 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD248 antibody

   TEM1 (Tumor endothelial marker 1), also named as CD248, Endosialin and CD164L1, is a C-type lectin-like domain (CTLD) containing type I transmembrane glycoprotein. It is now considered to be a highly selective marker for activated perivascular and stromal cells, detected in most cancers and at least some inflammatory disorders. CD248 plays a role in tumor angiogenesis. It is a potential diagnostic tool and therapeutic target of inflammatory and malignant disease. Two isoforms of human TEM1 exist. The calculated molecular weights of the two isoforms are 81 kDa and 46 kDa, respectively. Native TEM1 can be glycosylated, and the glycosylated form has a larger apparent molecular weight than 81 kDa.
 Product Categories/Family for anti-CD248 antibody    Cancer; Cardiovascular; Immunology
 Applications Tested/Suitable for anti-CD248 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-CD248 antibody    WB: 1:1000-1:10000
IHC: 1:50-1:500
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 Western Blot (WB) of anti-CD248 antibody    Western Blot analysis of HUVEC cells using TEM1 Monoclonal Antibody at dilution of 1:2000
anti-CD248 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CD248. It may not necessarily be applicable to this product.
 NCBI GI #    9966885
 NCBI GeneID    57124
 NCBI Accession #    NP_065137.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020404.2 [Other Products]
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 UniProt Primary Accession #    Q9HCU0 [Other Products]
 UniProt Secondary Accession #    Q2M2V5; Q3SX55; Q96KB6 [Other Products]
 UniProt Related Accession #    Q9HCU0 [Other Products]
 Molecular Weight    Calculated: 81kDa
Observed: 120kDa
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 NCBI Official Full Name    endosialin
 NCBI Official Synonym Full Names    CD248 molecule
 NCBI Official Symbol    CD248 [Similar Products]
 NCBI Official Synonym Symbols   
TEM1; CD164L1
[Similar Products]
 NCBI Protein Information    endosialin
 UniProt Protein Name    Endosialin
 UniProt Synonym Protein Names   
Tumor endothelial marker 1; CD_antigen: CD248
 Protein Family    Endosialin
 UniProt Gene Name    CD248 [Similar Products]
 UniProt Synonym Gene Names    CD164L1; TEM1 [Similar Products]
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 UniProt Comments for CD248    May play a role in tumor angiogenesis.
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 Research Articles on CD248    1. These findings identify novel protein interactions involving CLEC14A, CD93 and CD248 with MMRN2 as targetable components of vessel formation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD248 antibodyDiseases associated with anti-CD248 antibody
 Reference Product  PubMed Publications
 PDGFRB antibody  >3 publications with CD248 and PDGFRB
 ANTXR1 antibody  >1 publications with CD248 and ANTXR1
 SP1 antibody  >1 publications with CD248 and SP1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with CD248 and Inflammation
 Disease Models, Animal Antibodies  >7 publications with CD248 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >6 publications with CD248 and Neoplasms, Experimental
 Intestinal Neoplasms Antibodies  >3 publications with CD248 and Intestinal Neoplasms
 Fibrosis Antibodies  >2 publications with CD248 and Fibrosis
 Kidney Diseases Antibodies  >2 publications with CD248 and Kidney Diseases
 Ovarian Diseases Antibodies  >2 publications with CD248 and Ovarian Diseases
 Necrosis Antibodies  >2 publications with CD248 and Necrosis
 Immune System Diseases Antibodies  >2 publications with CD248 and Immune System Diseases
 Lung Diseases Antibodies  >1 publications with CD248 and Lung Diseases
Organs/Tissues associated with anti-CD248 antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >40 publications with CD248 and Vascular
 Embryonic Tissue Antibodies  >13 publications with CD248 and Embryonic Tissue
 Brain Antibodies  >7 publications with CD248 and Brain
 Muscle Antibodies  >6 publications with CD248 and Muscle
 Bone Antibodies  >5 publications with CD248 and Bone
 Lung Antibodies  >3 publications with CD248 and Lung
 Eye Antibodies  >2 publications with CD248 and Eye
 Lymph Node Antibodies  >2 publications with CD248 and Lymph Node
 Bone Marrow Antibodies  >2 publications with CD248 and Bone Marrow
 Kidney Antibodies  >2 publications with CD248 and Kidney
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