Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow CD25 rightarrow Monoclonal CD25  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • Hsp90 Antibody
 • Cross-linked N-terminal Telopeptides of type I collagen (NTx... ELISA Kit
 • Keratin, type II cytoskeletal 2 oral (KRT76) Recombinant Protein
 • Ferritin, Light Chain (FTL) Antibody
 • Cluster of differentiation 4 (CD4) ELISA Kit
 • Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) ELISA Kit
 • O-phosphoseryl-tRNA (SEPSECS) Antibody
 • Elastase (lasB) Antibody
 • gremlin 1, cysteine knot superfamily, homolog (Xenopus laevi... ELISA Kit
 • B-lymphocyte antigen CD20 (MS4A1) ELISA Kit
 • Myoglobin (MB) Antibody
 • Perforin 1 (PRF1) ELISA Kit
 • Cytochrome P450 3A4 (CYP3A4) ELISA Kit
 • Nascent polypeptide-associated complex subunit alpha, muscle... Recombinant Protein
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CD25 antibody :: Rat anti-Mouse CD25 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS520081
Testing Data
Unit / Price
0.25 mg  /  $260 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD25, Monoclonal Antibody

 Also Known As   

Anti-Mouse CD25, Purified (Clone PC61.5.3) (rat IgG1)

 Product Synonym Names    CD25, Purified (Clone PC61.5.3) (rat IgG1); Purified Anti-Mouse CD25 (IL-2R) Monoclonal Antibody
 Product Gene Name   

anti-CD25 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for P25094
 Clonality    Monoclonal
 Isotype    Rat IgG1
 Clone Number    PC61.5.3
 Host    Rat
 Species Reactivity    Mouse
Section Bar
 Specificity    CD25 (IL-2Ra, p55, Ly 43) (Mouse CD25 (IL-2 receptor, a chain))
 Form/Format    Purified (Purified Ig buffered in PBS and 0.02% NaN3. (Purified from bioreactor material via Protein G Chromatography))
 Concentration    Antibody Concentration: 1.0 mg/ml (lot specific)
Section Bar
 Immunogen    B6.1 CTL Cell line
 Donor    OFA rat spleen
 Fusion Partner    mouse myeloma line P3X63Ag8.653
 Presentation    250 ug purified Ig buffered in PBS and 0.02% NaN3
Section Bar
 Preparation and Storage    Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-CD25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for anti-CD25 antibody

   anti-mouse CD25 (IL-2R) monoclonal antibody reacts with the low affinity alpha chain of the interleukin-2 receptor antigen present on activated T and B cells in mice. MBS520081 inhibits IL-2 binding and IL-2 dependent proliferation. Applications include flow cytometry and immunoprecipitation. (1,2,3). This clone has also been referenced to work in immunohistochemistry (4).
 Applications Tested/Suitable for anti-CD25 antibody   

Immunohistochemistry (IHC), Flow Cytometry (FC), Immunoprecipitation (IP), Functional Assay (FA)

Section Bar
 Testing Data of anti-CD25 antibody    anti-CD25 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD25. It may not necessarily be applicable to this product.
 NCBI GI #    55904
 NCBI Accession #    CAA44297.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P25094 [Other Products]
 Molecular Weight    17,946 Da
Table BarTOPTable Bar
 NCBI Official Full Name    CD25
 UniProt Protein Name    Peripheral myelin protein 22
 UniProt Synonym Protein Names   
Protein CD25; SR13 myelin protein; Schwann cell membrane glycoprotein
 UniProt Gene Name    Pmp22 [Similar Products]
 UniProt Synonym Gene Names    Cd25; Pmp-22; PMP-22; SAG [Similar Products]
 UniProt Entry Name    PMP22_RAT
Section Bar
 UniProt Comments for CD25    Function: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

Subcellular location: Cell membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Found exclusively in the peripheral nervous system. Present in both myelinating and nonmyelinating Schwann cells. Found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). Ref.4

Developmental stage: Levels increase between embryonic day 21 (E21) and postnatal day 0 (PND0) and then gradually increase up to PND15. There is a slight increase between PND15 and adulthood. Ref.4

Induction: Strongly down-regulated in the initial phase after sciatic nerve injury.

Sequence similarities: Belongs to the PMP-22/EMP/MP20 family.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Diseases associated with anti-CD25 antibodyOrgans/Tissues associated with anti-CD25 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >662 publications with CD25 and Nervous System Diseases
 Peripheral Nervous System Diseases Antibodies  >635 publications with CD25 and Peripheral Nervous System Diseases
 Hereditary Sensory and Motor Neuropathy Antibodies  >542 publications with CD25 and Hereditary Sensory and Motor Neuropathy
 Charcot-Marie-Tooth Disease Antibodies  >525 publications with CD25 and Charcot-Marie-Tooth Disease
 Demyelinating Diseases Antibodies  >139 publications with CD25 and Demyelinating Diseases
 Disease Models, Animal Antibodies  >90 publications with CD25 and Disease Models, Animal
 Muscle Weakness Antibodies  >54 publications with CD25 and Muscle Weakness
 Brain Diseases Antibodies  >54 publications with CD25 and Brain Diseases
 Neoplasms Antibodies  >34 publications with CD25 and Neoplasms
 Nerve Degeneration Antibodies  >33 publications with CD25 and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >132 publications with CD25 and Muscle
 Brain Antibodies  >102 publications with CD25 and Brain
 Dorsal Root Ganglion Antibodies  >27 publications with CD25 and Dorsal Root Ganglion
 Embryonic Tissue Antibodies  >18 publications with CD25 and Embryonic Tissue
 Heart Antibodies  >9 publications with CD25 and Heart
 Kidney Antibodies  >7 publications with CD25 and Kidney
 Eye Antibodies  >5 publications with CD25 and Eye
 Lung Antibodies  >3 publications with CD25 and Lung
 Ovary Antibodies  >3 publications with CD25 and Ovary
 Prostate Antibodies  >2 publications with CD25 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions