NP_067371.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
27,820 Da
NCBI Official Full Name
programmed cell death 1 ligand 2
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Synonym Symbols
Btdc; B7-DC; PD-L2; F730015O22Rik [Similar Products]
NCBI Protein Information
programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; butyrophilin-like protein; programmed death ligand 2
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
UniProt Synonym Gene Names
B7dc; Btdc; Cd273; Pdl2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC [Similar Products]
UniProt Entry Name
PD1L2_MOUSE
UniProt Comments for CD273
PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: protein binding
Biological Process: negative regulation of T cell proliferation; negative regulation of interleukin-10 production; negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; positive regulation of T cell proliferation
Research Articles on CD273
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Disclaimer
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Pathways associated with anti-CD273 antibody
Diseases associated with anti-CD273 antibody
Organs/Tissues associated with anti-CD273 antibody
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