Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CD28 rightarrow Monoclonal CD28  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • HSA Antibody
 • Cardiac Troponin I (TnI) (TNNI3) Recombinant Protein
 • Vascular Endothelial Growth Factor A (VEGF-A) ELISA Kit
 • Hepatitis B Surface Antigen adw subtype (HBsAg) Recombinant Protein
 • SIALIDASE (nanH) Antibody
 • Angiotensin (1-7) (ANG (1 7) ) ELISA Kit
 • SULT1A3 Antibody
 • Apolipoprotein A5 (APOA5) ELISA Kit
 • MMP-1 22k Antibody
 • Protein ROS1 (ROS1), partial Recombinant Protein
 • Pregnancy Specific beta1 Glycoprotein 3 (PSG3) ELISA Kit
 • Cytochrome C Oxidase Subunit III (COX3) ELISA Kit
 • ATF4 Antibody
 • Zinc finger E-box-binding homeobox 1 (ZEB1) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CD28 antibody :: Mouse CD28 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211255 anti-CD28 antibody
Unit / Price
0.5 mg  /  $555 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD28, Monoclonal Antibody

★Popular Item★
 Also Known As   

MOUSE ANTI MOUSE CD28:Low Endotoxin

 Product Gene Name   

anti-CD28 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for P31041
 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    E18
 Host    Mouse
Section Bar
 Form/Format    Low Endotoxin
Purified IgG - liquid
 Concentration    IgG concentration 1.0 mg/ml (lot specific)
Section Bar
 Preparation    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
 Immunogen    Alternate immunisation with A20 cells expressing mCD28 and recombinant mCD28Ig.
Fusion Partners
 Target Species    Mouse
Section Bar
 Preparation and Storage    Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD28 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-CD28 antibody

   Mouse anti Mouse CD28 antibody, clone E18 recognizes murine CD28, a co-stimulatory cell surface molecule expressed by T cell subsets. Clone E18 has been shown to be able to stimulate murine T lymphocytes in combination with anti-mouse CD3.
 Applications Tested/Suitable for anti-CD28 antibody   

Flow cytometry (FC/FACS), Functional Assays (FN)

 Application Notes for anti-CD28 antibody    Flow Cytometry: Use10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD28. It may not necessarily be applicable to this product.
 NCBI GI #    161484597
 NCBI GeneID    12487
 NCBI Accession #    NP_031668.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_007642.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P31041 [Other Products]
 UniProt Secondary Accession #    Q6GSH7 [Other Products]
 UniProt Related Accession #    P31041 [Other Products]
 Molecular Weight    25,243 Da
Table BarTOPTable Bar
 NCBI Official Full Name    T-cell-specific surface glycoprotein CD28
 NCBI Official Synonym Full Names    CD28 antigen
 NCBI Official Symbol    Cd28 [Similar Products]
 NCBI Protein Information    T-cell-specific surface glycoprotein CD28
 UniProt Protein Name    T-cell-specific surface glycoprotein CD28
 UniProt Synonym Protein Names   
CD_antigen: CD28
 Protein Family    T-cell-specific surface glycoprotein
 UniProt Gene Name    Cd28 [Similar Products]
 UniProt Entry Name    CD28_MOUSE
Section Bar
 UniProt Comments for CD28    CD28: a type I plasma membrane protein Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Binds to B7-1 and -2. Expressed in T cells and plasma cells, but not in less mature B cells. Six splice-variant isoforms have been described.

Protein type: Membrane protein, integral; Cell surface

Cellular Component: membrane; integral to membrane; plasma membrane; immunological synapse; lipid raft; external side of plasma membrane

Molecular Function: protein homodimerization activity; protease binding; SH3/SH2 adaptor activity

Biological Process: positive regulation of isotype switching to IgG isotypes; positive regulation of mitosis; T cell activation; positive regulation of interleukin-2 biosynthetic process; negative thymic T cell selection; T cell receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of inflammatory response to antigenic stimulus; positive regulation of protein kinase B signaling cascade; T cell costimulation; positive regulation of alpha-beta T cell proliferation; positive regulation of T cell proliferation; immune response; positive regulation of transcription from RNA polymerase II promoter; regulatory T cell differentiation
Table BarTOPTable Bar
 Research Articles on CD28    1. CD28 costimulation is essential for conferring host protection during secondary N. brasiliensis infection.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CD28 antibodyPathways associated with anti-CD28 antibody
 Reference Product  PubMed Publications
 Cd80 antibody  >1813 publications with CD28 and Cd80
 Cd86 antibody  >1086 publications with CD28 and Cd86
 Lck antibody  >168 publications with CD28 and Lck
 Grb2 antibody  >29 publications with CD28 and Grb2
 Grap2 antibody  >6 publications with CD28 and Grap2
 Pik3r3 antibody  >2 publications with CD28 and Pik3r3
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 CD28 Co-stimulation Pathway antibodies  CD28 Co-stimulation Pathway Diagram
 CD28 Dependent PI3K/Akt Signaling Pathway antibodies  CD28 Dependent PI3K/Akt Signaling Pathway Diagram
 CD28 Dependent Vav1 Pathway antibodies  CD28 Dependent Vav1 Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
Diseases associated with anti-CD28 antibodyOrgans/Tissues associated with anti-CD28 antibody
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >1237 publications with CD28 and Autoimmune Diseases
 Necrosis Antibodies  >849 publications with CD28 and Necrosis
 Inflammation Antibodies  >806 publications with CD28 and Inflammation
 HIV Infections Antibodies  >453 publications with CD28 and HIV Infections
 Arthritis, Rheumatoid Antibodies  >358 publications with CD28 and Arthritis, Rheumatoid
 Lung Diseases Antibodies  >313 publications with CD28 and Lung Diseases
 Lymphoma Antibodies  >282 publications with CD28 and Lymphoma
 Carcinoma Antibodies  >233 publications with CD28 and Carcinoma
 Asthma Antibodies  >199 publications with CD28 and Asthma
 Liver Diseases Antibodies  >163 publications with CD28 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >559 publications with CD28 and Spleen
 Bone Antibodies  >421 publications with CD28 and Bone
 Bone Marrow Antibodies  >375 publications with CD28 and Bone Marrow
 Lung Antibodies  >347 publications with CD28 and Lung
 Thymus Antibodies  >343 publications with CD28 and Thymus
 Skin Antibodies  >314 publications with CD28 and Skin
 Joint Antibodies  >151 publications with CD28 and Joint
 Embryonic Tissue Antibodies  >56 publications with CD28 and Embryonic Tissue
 Mammary Gland Antibodies  >3 publications with CD28 and Mammary Gland
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions