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anti-CD31 antibody :: Mouse CD31 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS215179 anti-CD31 antibody
Unit / Price
2 mL  /  $430 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD31, Monoclonal Antibody

 Also Known As   

MOUSE ANTI PIG CD31

 Product Gene Name   

anti-CD31 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q95242
 Clonality    Monoclonal
 Isotype    IgM
 Clone Number    LCI-9
 Host    Mouse
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 Form/Format    Tissue Culture Supernatant - liquid
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 Perservative Stabilisers    0.09% Sodium Azide
 Target Species    Pig
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CD31 antibody

   Mouse anti Pig CD31 antibody, clone LCI-9 recognises porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1. Porcine CD31 is a 740 amino acid ~140kDa single pass type 1 transmembrane glycoprotein bearing six Ig-like C2-type domains. CD31 is expressed by various cell types, but particularly by endothelial cells where it is required for leukocyte transendothelial migration (UniProt:Q95242). Mouse anti Pig CD31 antibody, clone LCI-9 has been used successfully for recognition of porcine CD31 by flow cytometry (Peterson et al. 2005) and immunofluorescence microscopy (Nasu et al. 1999).
 Applications Tested/Suitable for anti-CD31 antibody   

Immunohistology Frozen, Flow cytometry (FC/FACS)

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NCBI/Uniprot data below describe general gene information for CD31. It may not necessarily be applicable to this product.
 NCBI GI #    47522670
 NCBI GeneID    396941
 NCBI Accession #    NP_999072.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_213907.1 [Other Products]
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 UniProt Primary Accession #    Q95242 [Other Products]
 UniProt Related Accession #    Q95242 [Other Products]
 Molecular Weight    82,379 Da
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 NCBI Official Full Name    platelet endothelial cell adhesion molecule
 NCBI Official Symbol    PECAM1 [Similar Products]
 NCBI Official Synonym Symbols   
CD31; PECAM-1
[Similar Products]
 NCBI Protein Information    platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule (CD31 antigen); type I transmembrane endothelial adhesion molecule
 UniProt Protein Name    Platelet endothelial cell adhesion molecule
 UniProt Synonym Protein Names   
CD_antigen: CD31
 UniProt Gene Name    PECAM1 [Similar Products]
 UniProt Synonym Gene Names    PECAM-1 [Similar Products]
 UniProt Entry Name    PECA1_PIG
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 UniProt Comments for CD31    Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Modulates BDKRB2 activation. Induces susceptibility to atherosclerosis ().
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD31 antibodyPathways associated with anti-CD31 antibody
 Reference Product  PubMed Publications
 CD34 antibody  >968 publications with CD31 and CD34
 TNF antibody  >201 publications with CD31 and TNF
 VWF antibody  >178 publications with CD31 and VWF
 VEGFA antibody  >120 publications with CD31 and VEGFA
 NOS3 antibody  >53 publications with CD31 and NOS3
 CTNNB1 antibody  >50 publications with CD31 and CTNNB1
 SELE antibody  >12 publications with CD31 and SELE
 ESAM antibody  >3 publications with CD31 and ESAM
 JUP antibody  >3 publications with CD31 and JUP
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
Diseases associated with anti-CD31 antibodyOrgans/Tissues associated with anti-CD31 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >635 publications with CD31 and Cardiovascular Diseases
 Inflammation Antibodies  >511 publications with CD31 and Inflammation
 Necrosis Antibodies  >406 publications with CD31 and Necrosis
 Neoplasms, Experimental Antibodies  >264 publications with CD31 and Neoplasms, Experimental
 Lung Diseases Antibodies  >247 publications with CD31 and Lung Diseases
 Heart Diseases Antibodies  >235 publications with CD31 and Heart Diseases
 Breast Neoplasms Antibodies  >209 publications with CD31 and Breast Neoplasms
 Lung Neoplasms Antibodies  >193 publications with CD31 and Lung Neoplasms
 Liver Diseases Antibodies  >181 publications with CD31 and Liver Diseases
 Liver Neoplasms Antibodies  >157 publications with CD31 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3038 publications with CD31 and Blood
 Muscle Antibodies  >696 publications with CD31 and Muscle
 Embryonic Tissue Antibodies  >512 publications with CD31 and Embryonic Tissue
 Lung Antibodies  >443 publications with CD31 and Lung
 Heart Antibodies  >359 publications with CD31 and Heart
 Skin Antibodies  >343 publications with CD31 and Skin
 Liver Antibodies  >308 publications with CD31 and Liver
 Lymph Antibodies  >256 publications with CD31 and Lymph
 Kidney Antibodies  >240 publications with CD31 and Kidney
 Lymph Node Antibodies  >223 publications with CD31 and Lymph Node
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