NP_598415.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,263 Da
NCBI Official Full Name
hematopoietic progenitor cell antigen CD34 isoform 2
NCBI Official Synonym Full Names
CD34 antigen
NCBI Official Synonym Symbols
NCBI Protein Information
hematopoietic progenitor cell antigen CD34; cluster designation 34
UniProt Protein Name
Hematopoietic progenitor cell antigen CD34
UniProt Synonym Protein Names
CD_antigen: CD34
UniProt Entry Name
CD34_MOUSE
UniProt Comments for CD34
CD34: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. Belongs to the CD34 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface; Membrane protein, integral
Cellular Component: intercellular bridge; cell surface; membrane; perinuclear region of cytoplasm; lysosome; apical plasma membrane; cytoplasm; integral to membrane; basal plasma membrane; extracellular region; plasma membrane; external side of plasma membrane
Molecular Function: sulfate binding; carbohydrate binding; transcription factor binding
Biological Process: positive regulation of odontogenesis; positive regulation of angiogenesis; cell-cell adhesion; regulation of blood pressure; endothelial cell proliferation; negative regulation of nitric oxide biosynthetic process; tissue homeostasis; negative regulation of blood coagulation; hemopoiesis; negative regulation of tumor necrosis factor production; cell adhesion; leukocyte migration; positive regulation of interleukin-10 production
Research Articles on CD34
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-CD34 antibody
Diseases associated with anti-CD34 antibody
Organs/Tissues associated with anti-CD34 antibody
|