View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-CD49d antibody :: Mouse CD49d Monoclonal Antibody Catalog # MBS219400 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CD49d, Monoclonal Antibody Popular Item Full Product Name MOUSE ANTI RAT CD49d Product Gene Name anti-CD49d antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG2a Clone Number MRalpha4-1 Host Mouse Form/Format PurifiedPurified IgG - liquid Concentration IgG concentration 1.0mg/ml (lot specific) Perservative Stabilisers 0.09% Sodium Azide (NaN3) Preparation Buffer Solution Phosphate buffered saline Target Species Rat Preparation and Storage Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.Shelf Life: 18 months from date of despatch. Other Notes Small volumes of anti-CD49d antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-CD49d antibody Mouse anti Rat CD49d monoclonal antibody, clone MRalpha4-1 recognizes rat CD49d, otherwise known as integrin alpha 4 chain/VLA-4, a ~150kDa single pass type-1 transmembrane glycoprotein and member of the integrin alpha chain family, which acts as a receptor for fibronectin and CD106 (VCAM-1). CD49d is expressed broadly on T and B lymphocytes, monocytes, thymocytes, mast cells and dendritic cells and is involved in cell-cell interactions, mononuclear cell trafficking to sites of endothelial inflammation, and the adhesion of cells to the extracellular matrix. Clone MRalpha4-1 inhibits the in vitro and in vivo functions of CD49d (Yasuda, M. et al.). Studies have shown that in rat Peyer's patches, clone MRalpha4-1 inhibits the rolling and adherence of lymphocytes to postcapillary venules (PCV), and significantly inhibits the transendothelial migration of T lymphocytes (Tsuzuki, Y. et al.). Applications Tested/Suitable for anti-CD49d antibody Flow cytometry (FC/FACS), Immunoprecipitation (IP) Application Notes for anti-CD49d antibody Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/200 Testing Data of anti-CD49d antibody Staining of Rat peripheral blood lymphocytes with Mouse anti Rat CD49d:RPE (MBS219473) Testing Data of anti-CD49d antibody Staining of Rat peripheral blood lymphocytes with Mouse anti Rat CD49d : Alexa Fluor 488 (MBS219400A488) Testing Data of anti-CD49d antibody Staining of Rat peripheral blood lymphocytes with Mouse anti Rat CD49d:FITC (MBS219580) Testing Data of anti-CD49d antibody Staining of Rat peripheral blood lymphocytes with Mouse anti Rat CD49d:Low Endotoxin (MBS219551) Testing Data of anti-CD49d antibody Staining of Rat peripheral blood lymphocytes with Mouse anti Rat CD49d : Alexa Fluor 647 (MBS219400A647) TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP