Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CD70 rightarrow Monoclonal CD70  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • MC2R-ACTHR (MC2R ) Antibody
 • Cholesterol side-chain cleavage enzyme (CYP11A1) Recombinant Protein
 • 2, 3-bisphosphoglycerate mutase (BPGM) ELISA Kit
 • MBTPS1 Antibody
 • kallikrein-related peptidase 6 (KLK6) ELISA Kit
 • Neutrophil Gelatinase Associated Lipocalin (NGAL) ELISA Kit
 • CD4 protein Recombinant Protein
 • RGS2 Recombinant Protein
 • Stromal Cell Derived Factor 1alpha (CXCL12) Antibody
 • secretoglobin, family 1D, member 1 (SCGB1D1) ELISA Kit
 • Infectious bronchitis virus (IBV) Antibody
 • 40S ribosomal protein S13 (RPS13) Antibody
 • ku86 ELISA Kit
 • G Protein Alpha Inhibiting Activity Polypeptide 3 (GNalphaI3... ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CD70 antibody :: Rat anti-Mouse CD70 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS520560 anti-CD70 antibody
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD70, Monoclonal Antibody

 Also Known As   

Anti-Mouse CD70 (clone: TAN 1-7), Biotin, (Mouse IgG1)

 Product Synonym Names    CD70 (clone: TAN 1-7), Biotin, (Mouse IgG1)
 Product Gene Name   

anti-CD70 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 19; NC_000019.9 (6582969..6591163, complement). Location: 19p13
 OMIM    602840
 3D Structure    ModBase 3D Structure for P32970
Section Bar
 Clonality    Monoclonal
 Isotype    Rat IgG2a
 Clone Number    TAN 1-7
 Host    Rat
 Species Reactivity    Mouse
Section Bar
 Specificity    CD70
 Form/Format    Biotin
Section Bar
Section Bar
 Other Notes    Small volumes of anti-CD70 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-CD70 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD70. It may not necessarily be applicable to this product.
 NCBI GI #    4507605
 NCBI GeneID    970
 NCBI Accession #    NP_001243.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001252.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P32970 [Other Products]
 UniProt Secondary Accession #    Q96J57 [Other Products]
 UniProt Related Accession #    P32970 [Other Products]
 Molecular Weight    21,118 Da
Table BarTOPTable Bar
 NCBI Official Full Name    CD70 antigen
 NCBI Official Synonym Full Names    CD70 molecule
 NCBI Official Symbol    CD70 [Similar Products]
 NCBI Official Synonym Symbols   
CD27L; CD27LG; TNFSF7
[Similar Products]
 NCBI Protein Information    CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7
 UniProt Protein Name    CD70 antigen
 UniProt Synonym Protein Names   
CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7
 Protein Family    CD70 antigen
 UniProt Gene Name    CD70 [Similar Products]
 UniProt Synonym Gene Names    CD27L; CD27LG; TNFSF7; CD27-L [Similar Products]
 UniProt Entry Name    CD70_HUMAN
Section Bar
 NCBI Summary for CD70    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for CD70    Function: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Subunit structure: Homotrimer

Probable.

Subcellular location: Membrane; Single-pass type II membrane protein.

Sequence similarities: Belongs to the tumor necrosis factor family.
Table BarTOPTable Bar
 Research Articles on CD70    1. These results highlight the importance of the CD27-CD70 costimulation pathway for the development of CMV-specific T cell immunity during acute and persistent infection.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CD70 antibodyPathways associated with anti-CD70 antibody
 Reference Product  PubMed Publications
 CD27 antibody  >245 publications with CD70 and CD27
 CD40 antibody  >110 publications with CD70 and CD40
 TNFSF4 antibody  >30 publications with CD70 and TNFSF4
 TNFSF8 antibody  >14 publications with CD70 and TNFSF8
 DNMT1 antibody  >12 publications with CD70 and DNMT1
 TNFSF9 antibody  >9 publications with CD70 and TNFSF9
 CD40LG antibody  >5 publications with CD70 and CD40LG
 SIVA1 antibody  >2 publications with CD70 and SIVA1
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-CD70 antibodyOrgans/Tissues associated with anti-CD70 antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >140 publications with CD70 and Immune System Diseases
 Necrosis Antibodies  >133 publications with CD70 and Necrosis
 Neoplasms Antibodies  >127 publications with CD70 and Neoplasms
 Inflammation Antibodies  >34 publications with CD70 and Inflammation
 Death Antibodies  >28 publications with CD70 and Death
 Neoplasms, Experimental Antibodies  >26 publications with CD70 and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >22 publications with CD70 and Nervous System Diseases
 Kidney Diseases Antibodies  >19 publications with CD70 and Kidney Diseases
 Brain Diseases Antibodies  >10 publications with CD70 and Brain Diseases
 Lung Diseases Antibodies  >9 publications with CD70 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >19 publications with CD70 and Kidney
 Intestine Antibodies  >6 publications with CD70 and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions