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anti-CD79B antibody :: Mouse CD79b Preservative Free Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS603208 anti-CD79B antibody
Unit / Price
0.1 mg  /  $565 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD79b Preservative Free, Monoclonal Antibody

★Popular Item★
 Also Known As   

CD79b Preservative Free (BCR-Ig beta)

 Product Synonym Names    Anti -CD79b Preservative Free (BCR-Ig beta)
 Product Gene Name   

anti-CD79B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 17; NC_000017.10 (62006098..62009704, complement). Location: 17q23
 OMIM    147245
 3D Structure    ModBase 3D Structure for P40259
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    7H118
 Host    Mouse
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 Specificity    Recognizes the extracellular part of the BCR complex beta chain (CD79b) which has a molecular weight of approximately 38kD.
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2 No preservatives.
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 Immunogen    Membrane preparation of human B prolymphocytic leukemia cells
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-CD79B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD79B antibody

   Human CD79b is the B cell antigen receptor Igb chain (BCR-Igb) which associates with B cell antigen receptor Ig a chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Iga/Igb heterodimer transduces signals.
 Product Categories/Family for anti-CD79B antibody    Antibodies; Abs to CD Markers
 Applications Tested/Suitable for anti-CD79B antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

 Application Notes for anti-CD79B antibody    Suitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry and Western Blot.
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NCBI/Uniprot data below describe general gene information for CD79B. It may not necessarily be applicable to this product.
 NCBI GI #    1087009
 NCBI GeneID    974
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 UniProt Primary Accession #    P40259 [Other Products]
 UniProt Secondary Accession #    Q53FS2; Q9BU06 [Other Products]
 UniProt Related Accession #    P40259; Q6PIS4 [Other Products]
 Molecular Weight    26,048 Da [Similar Products]
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 NCBI Official Full Name    CD79b
 NCBI Official Synonym Full Names    CD79b molecule, immunoglobulin-associated beta
 NCBI Official Symbol    CD79B [Similar Products]
 NCBI Official Synonym Symbols   
B29; IGB; AGM6
[Similar Products]
 NCBI Protein Information    B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta)
 UniProt Protein Name    B-cell antigen receptor complex-associated protein beta chain
 UniProt Synonym Protein Names   
B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein
 Protein Family    B-cell antigen receptor complex-associated protein
 UniProt Gene Name    CD79B [Similar Products]
 UniProt Synonym Gene Names    B29; IGB [Similar Products]
 UniProt Entry Name    CD79B_HUMAN
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 NCBI Summary for CD79B    The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
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 UniProt Comments for CD79B    Ig-beta: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79B are the cause of agammaglobulinemia type 6 (AGM6). It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q23

Cellular Component: nucleoplasm; Golgi apparatus; integral to plasma membrane; cytoplasm; plasma membrane; B cell receptor complex; external side of plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: B cell receptor signaling pathway; immune response; signal transduction

Disease: Agammaglobulinemia 6, Autosomal Recessive
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 Research Articles on CD79B    1. STN produced significant antitumor effects in a mouse xenograft model of CD79A/B-mutated DLBCL.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD79B antibodyPathways associated with anti-CD79B antibody
 Reference Product  PubMed Publications
 CD79A antibody  >521 publications with CD79B and CD79A
 CD5 antibody  >90 publications with CD79B and CD5
 CD19 antibody  >83 publications with CD79B and CD19
 SYK antibody  >30 publications with CD79B and SYK
 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
Diseases associated with anti-CD79B antibodyOrgans/Tissues associated with anti-CD79B antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >311 publications with CD79B and Neoplasms
 Immune System Diseases Antibodies  >301 publications with CD79B and Immune System Diseases
 Lymphoma Antibodies  >213 publications with CD79B and Lymphoma
 Lymphoma, B-Cell Antibodies  >184 publications with CD79B and Lymphoma, B-Cell
 Leukemia Antibodies  >156 publications with CD79B and Leukemia
 Lymphoma, Non-Hodgkin Antibodies  >139 publications with CD79B and Lymphoma, Non-Hodgkin
 Leukemia, Lymphocytic, Chronic, B-Cell Antibodies  >80 publications with CD79B and Leukemia, Lymphocytic, Chronic, B-Cell
 Precursor Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >27 publications with CD79B and Precursor Cell Lymphoblastic Leukemia-Lymphoma
 Hodgkin Disease Antibodies  >27 publications with CD79B and Hodgkin Disease
 Skin Neoplasms Antibodies  >22 publications with CD79B and Skin Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >351 publications with CD79B and Blood
 Bone Antibodies  >105 publications with CD79B and Bone
 Lymph Node Antibodies  >73 publications with CD79B and Lymph Node
 Lymph Antibodies  >70 publications with CD79B and Lymph
 Spleen Antibodies  >46 publications with CD79B and Spleen
 Skin Antibodies  >30 publications with CD79B and Skin
 Intestine Antibodies  >18 publications with CD79B and Intestine
 Thymus Antibodies  >18 publications with CD79B and Thymus
 Lung Antibodies  >17 publications with CD79B and Lung
 Vascular Antibodies  >13 publications with CD79B and Vascular
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