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anti-THY1 antibody :: Rat anti-Mouse CD90/Thy-1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS673466 anti-THY1 antibody
Unit / Price
0.1 mg  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD90/Thy-1 (THY1), Monoclonal Antibody

 Also Known As   

Rat Anti-Mouse CD90/Thy-1-SPRD

 Product Synonym Names    Rat Anti-Mouse CD90/Thy-1 - SpectralRed-Labeled; Rat Anti-Mouse CD90/Thy-1
 Product Gene Name   

anti-THY1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_010451.2 (52628071..52629528)
 3D Structure    ModBase 3D Structure for B9ZSM8
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 Clonality    Monoclonal
 Isotype    Rat IgG2c kappa
 Clone Number    G7
 Host    Rat
 Species Reactivity    Mouse
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 Specificity    Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A)
CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain.^1-4 It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains.^1,2 MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex.^1,5-7 The MAb has also been reported to promote apoptosis of thymocytes and CTL clones,^4,7 and to mediate adhesion of thymocytes to thymic stroma.^8
 Form/Format    Spectral Red (SPRD) Conjugate
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 Characterization    To ensure lot-to-lot consistency, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference reagent. Representative data are included in this product insert.
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 Preparation and Storage    The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg or 0.1mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The R-phycoerythrin (R-PE) and allophycocyanin (APC) conjugates are supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C.
With the exception of the low endotoxin, azide-free product, the vials should be stored at 2-8 degree C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
 Other Notes    Small volumes of anti-THY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-THY1 antibody   

Flow Cytometry; Immunocytochemistry; Immunohistochemistry (Acetone Fixed/Frozen Sections)

 Application Notes for anti-THY1 antibody    Research Application(s): In vitro T cell activation
Induction of apoptosis

Flow Cytometry Suggested Dilution: <= 0.2 ug/10^6 cells
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NCBI/Uniprot data below describe general gene information for THY1. It may not necessarily be applicable to this product.
 NCBI GI #    224697007
 NCBI GeneID    100271931
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 UniProt Primary Accession #    B9ZSM8 [Other Products]
 Molecular Weight    17,955 Da [Similar Products]
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 NCBI Official Full Name    CD90 protein
 NCBI Official Symbol    THY1 [Similar Products]
 NCBI Official Synonym Symbols   
CD90
[Similar Products]
 NCBI Protein Information    thy-1 membrane glycoprotein
 UniProt Protein Name    CD90 protein
 Protein Family    Thy-1 membrane glycoprotein
 UniProt Gene Name    CD90 [Similar Products]
 UniProt Entry Name    B9ZSM8_PIG
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Product References and Citations for anti-THY1 antibody

   1. Gunter, K., T. Malek, and E. Shevach. 1984. T-cell activating properties of an anti-Thy-1 monoclonal antibody. J. Exp. Med. 159:716.
2. Williams, A.F., and J. Gagnon. 1982. Science 216:696.
3. Kroczek, R.A., K.C. Gunter, R.N. Germain, and E.M. Shevach. 1986. Nature 322:181.
4. Hueber, A.O., G. Raposo, M. Pierres, and H.-T. He. 1994. J. Exp. Med. 179:785.
5. Tentori, L., D.M. Pardoll, J.C. Zunigaq, J. Hu-Li, W.E. Paul, J.A. Bluestone, and A.M. Kruisbeek. 1988. J. Immunol. 140:1089.
6. Sugiyama, E., A. Cantagrei, T. Reno, F. Stafford-Brady, E.T.H. Yeh, and J.V. Bonventre. 1990. Cell. Immunol. 130:271.
7. Ucker, D.S., J. Meyers, and P.S. Obermuller. 1992. J. Immunol. 149:1583.
8. He, H.-T., P. Naquet, D. Caillol, and M. Pierres. 1991. J. Exp. Med. 173:515.
9. Kruisbeek, A.M., and E. Shevach. 1991. Proliferative assays for T cell function. In: Current Protocols in Immunology. Coligan, J., A. Kruisbeek, D. Margulies, E.M. Shevach, and W. Strober. John Wiley & Sons, New York, NY, pp. 3.12.1-3.12.14.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-THY1 antibodyDiseases associated with anti-THY1 antibody
 Products by Pathway  Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >172 publications with THY1 and Neoplasms
 Kidney Diseases Antibodies  >168 publications with THY1 and Kidney Diseases
 Autoimmune Diseases Antibodies  >52 publications with THY1 and Autoimmune Diseases
 Inflammation Antibodies  >50 publications with THY1 and Inflammation
 Leukemia Antibodies  >48 publications with THY1 and Leukemia
 Lymphoma Antibodies  >47 publications with THY1 and Lymphoma
 Death Antibodies  >39 publications with THY1 and Death
 Necrosis Antibodies  >35 publications with THY1 and Necrosis
 Fibrosis Antibodies  >32 publications with THY1 and Fibrosis
 Carcinoma Antibodies  >31 publications with THY1 and Carcinoma
Organs/Tissues associated with anti-THY1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >605 publications with THY1 and Blood
 Spleen Antibodies  >278 publications with THY1 and Spleen
 Brain Antibodies  >101 publications with THY1 and Brain
 Lymph Antibodies  >99 publications with THY1 and Lymph
 Lymph Node Antibodies  >98 publications with THY1 and Lymph Node
 Liver Antibodies  >91 publications with THY1 and Liver
 Lung Antibodies  >54 publications with THY1 and Lung
 Muscle Antibodies  >54 publications with THY1 and Muscle
 Skin Antibodies  >43 publications with THY1 and Skin
 Embryonic Tissue Antibodies  >28 publications with THY1 and Embryonic Tissue
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