CAA74663.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,109 Da
NCBI Official Full Name
CD94, partial
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily D, member 1
NCBI Official Synonym Symbols
NCBI Protein Information
natural killer cells antigen CD94; KP43; CD94 antigen; NK cell receptor
UniProt Protein Name
Natural killer cells antigen CD94
UniProt Synonym Protein Names
KP43; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor; CD_antigen: CD94
UniProt Synonym Gene Names
UniProt Entry Name
KLRD1_HUMAN
NCBI Summary for CD94
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CD94
KLRD1: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: plasma membrane; integral to membrane; receptor complex; external side of plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; carbohydrate binding
Biological Process: regulation of immune response; cell surface receptor linked signal transduction; natural killer cell mediated immunity; innate immune response
Product References and Citations for anti-CD94 antibody
J. Aramburu, et al, (1990) J Immunol 144: 3238-3247. J. Aramburu, et al, J Immunol (1991) 147: 714-721. A. Moretta, et al, J Exp Med (1994) 180: 545-555. C. Chang, et al, Eur J Immunol (1995) 25: 2433-2437. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p.1437-1439.
Research Articles on CD94
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Products associated with anti-CD94 antibody
Pathways associated with anti-CD94 antibody
Diseases associated with anti-CD94 antibody
Organs/Tissues associated with anti-CD94 antibody
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