Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CDC20 rightarrow Monoclonal CDC20  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • heparan sulfate proteoglycan 2 (HSPG2) ELISA Kit
 • anti-antineutrophilicperinu clearantibody (pANCA) ELISA Kit
 • Serine-threonine-protein kinase ATG1 (ATG1) (CAGL0L06006g) Recombinant Protein
 • CD334 (FGFR4) Antibody
 • Cell division cycle protein 123 homolog (CDC123) ELISA Kit
 • insulin-like growth factor binding protein 7 (IGFBP-7) ELISA Kit
 • Lassa Virus (LV) PCR Kit
 • reticulocalbin 3, EF-hand calcium binding domain (RCN3) ELISA Kit
 • AMYLIN (IAPP) Antibody
 • CD27 molecule Antibody
 • MTMR7 cDNA Clone
 • CLN6 Antibody
 • Heat Shock 70kDa Protein 8 (HSPA8) ELISA Kit
 • Myosin Heavy Chain (MHC) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CDC20 antibody :: Mouse anti-Human CDc20 (Cell Division Cycle Protein 20) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS439601
Unit / Price
0.02 mg (With BSA & Azide at 0.2mg/ml)  /  $190 +1 FREE 8GB USB
7 ml (Prediluted)  /  $270 +1 FREE 8GB USB
0.1 mg (With BSA & Azide at 0.2mg/ml)  /  $300 +1 FREE 8GB USB
0.1 mg (Without BSA & Azide at 1mg/ml)  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CDc20 (Cell Division Cycle Protein 20), Monoclonal Antibody

★Popular Item★
 Also Known As   

CDc20 (Cell Division Cycle Protein 20) Mouse Monoclonal Antibody

 Product Synonym Names    CDC20, CDC20A, p55CDC, P55CDC-LSB
 Product Gene Name   

anti-CDC20 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    603618
 3D Structure    ModBase 3D Structure for Q12834
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1, kappa
 Clone Number    CDC20/1102
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Specificity    Cyclins, regulatory subunits, which associate with kinases, control many of the important steps in cell cycle progression. The Cdc2 protein kinase (p34Cdc2) exhibits protein kinase activity in vitro and exists in a complex with both cyclin B and a protein homologous to p13SUC1. Cdc2 kinase is the active subunit of the M phase promoting factor (MPF) and the M phase-specific Histone H1 kinase. The p34Cdc2/cyclin B complex is required for the G2 to M transition. An additional cell cycle-dependent protein kinase, termed p55cdc, exhibits a high degree of homology with the S. cerevisiae proteins Cdc20 and Cdc4. The p55cdc transcript is readily detectable in a variety of cultured cell lines in growth phase, but disappears when cell growth is chemically arrested.
 Form/Format    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Section Bar
 Cellular Localization    Cytoplasmic
 Immunogen    Recombinant human Cdc20 protein
 Hu-Chromosome Location    1p34.2
 Positive Control    Ramos or HeLa cells. Tonsil or gastric carcinoma.
Section Bar
 Preparation and Storage    Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
 Other Notes    Small volumes of anti-CDC20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-CDC20 antibody   

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin

 Application Notes for anti-CDC20 antibody    Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Section Bar
 Immunohistochemistry (IHC) of anti-CDC20 antibody    Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with CDC20 Monoclonal Antibody (CDC20/1102)
anti-CDC20 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-CDC20 antibody    Formalin-fixed, paraffin-embedded human Tonsil stained with CDC20 Monoclonal Antibody (CDC20/1102)
anti-CDC20 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CDC20. It may not necessarily be applicable to this product.
 NCBI GI #    118402582
 NCBI GeneID    991
 NCBI Accession #    NP_001246.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001255.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q12834 [Other Products]
 UniProt Secondary Accession #    Q5JUY4; Q9BW56; Q9UQI9; B2R6Z6; D3DPJ1 [Other Products]
 UniProt Related Accession #    Q12834 [Other Products]
 Molecular Weight    55kDa
Table BarTOPTable Bar
 NCBI Official Full Name    cell division cycle protein 20 homolog
 NCBI Official Synonym Full Names    cell division cycle 20
 NCBI Official Symbol    CDC20 [Similar Products]
 NCBI Official Synonym Symbols   
CDC20A; p55CDC; bA276H19.3
[Similar Products]
 NCBI Protein Information    cell division cycle protein 20 homolog
 UniProt Protein Name    Cell division cycle protein 20 homolog
 UniProt Synonym Protein Names   
p55CDC
 Protein Family    Cell division cycle protein
 UniProt Gene Name    CDC20 [Similar Products]
 UniProt Entry Name    CDC20_HUMAN
Section Bar
 NCBI Summary for CDC20    CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for CDC20    CDC20: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. Found in a complex with CDC20, CDC27, SPATC1 and TUBG1. Interacts with SPATC1. Interacts with NEUROD2. Interacts with MAD2L1 and BUB1B. The phosphorylated form interacts with APC/C. Interacts with NINL. May interact with MAD2L2. Interacts with CDK5RAP2. Interacts with isoform 1 of NEK2. Belongs to the WD repeat CDC20/Fizzy family.

Protein type: Ubiquitin conjugating system; Cell cycle regulation

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: anaphase-promoting complex; cytoplasm; cytosol; nucleoplasm; nucleus; spindle

Molecular Function: enzyme binding; protein binding; protein C-terminus binding

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of synaptic plasticity; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; sister chromatid cohesion
Table BarTOPTable Bar
 

Product References and Citations for anti-CDC20 antibody

   Sironi L et al. 2001. EMBO J. 20(22):6371-82.
Section Bar
 Research Articles on CDC20    1. The presence of this segment correlates with SAC activity and efficient binding of CDC20 but not of MAD1 to kinetochores.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CDC20 antibodyPathways associated with anti-CDC20 antibody
 Reference Product  PubMed Publications
 CCNB1 antibody  >124 publications with CDC20 and CCNB1
 MAD2L1 antibody  >115 publications with CDC20 and MAD2L1
 BUB3 antibody  >67 publications with CDC20 and BUB3
 CDC27 antibody  >33 publications with CDC20 and CDC27
 BUB1B antibody  >23 publications with CDC20 and BUB1B
 CDC23 antibody  >19 publications with CDC20 and CDC23
 CDC16 antibody  >13 publications with CDC20 and CDC16
 ANAPC2 antibody  >8 publications with CDC20 and ANAPC2
 PTTG1 antibody  >6 publications with CDC20 and PTTG1
 ANAPC4 antibody  >5 publications with CDC20 and ANAPC4
 Products by Pathway  Pathway Diagram
 APC-Cdc20 Mediated Degradation Of Nek2A Pathway antibodies  APC-Cdc20 Mediated Degradation Of Nek2A Pathway Diagram
 APC/C Complex Pathway antibodies  APC/C Complex Pathway Diagram
 APC/C Complex Pathway antibodies  APC/C Complex Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
Diseases associated with anti-CDC20 antibodyOrgans/Tissues associated with anti-CDC20 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >51 publications with CDC20 and Carcinoma
 Breast Neoplasms Antibodies  >22 publications with CDC20 and Breast Neoplasms
 Adenocarcinoma Antibodies  >20 publications with CDC20 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >19 publications with CDC20 and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >15 publications with CDC20 and Lung Neoplasms
 Lung Diseases Antibodies  >13 publications with CDC20 and Lung Diseases
 Neoplasms, Experimental Antibodies  >12 publications with CDC20 and Neoplasms, Experimental
 Liver Diseases Antibodies  >11 publications with CDC20 and Liver Diseases
 Liver Neoplasms Antibodies  >10 publications with CDC20 and Liver Neoplasms
 Prostatic Neoplasms Antibodies  >10 publications with CDC20 and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with CDC20 and Brain
 Lung Antibodies  >26 publications with CDC20 and Lung
 Liver Antibodies  >25 publications with CDC20 and Liver
 Blood Antibodies  >19 publications with CDC20 and Blood
 Prostate Antibodies  >14 publications with CDC20 and Prostate
 Bone Antibodies  >12 publications with CDC20 and Bone
 Bone Marrow Antibodies  >8 publications with CDC20 and Bone Marrow
 Muscle Antibodies  >7 publications with CDC20 and Muscle
 Kidney Antibodies  >7 publications with CDC20 and Kidney
 Nerve Antibodies  >6 publications with CDC20 and Nerve
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions