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anti-CEA antibody :: Mouse anti-CEA 100% CEA Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS530761 anti-CEA antibody
Unit / Price
1 mg  /  $220 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CEA, Monoclonal Antibody

★Popular Item★
 Also Known As   

CEA antibody (in PBS)

 Product Synonym Names    Monoclonal CEA; Anti-CEA; Carcinoembryonic Antigen
 Product Gene Name   

anti-CEA antibody

[Similar Products]
 Matching Pairs    Capture Antibody: CEA Clone #M111147 (MBS530175)
Detection Antibody: CEA Clone #M111146 (MBS530761)
Comments: Excellent pair for ELISA
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    163980
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    M111146
 Host    Mouse
 Species Reactivity    CEA 100%
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 Form/Format    Chromatographically purified, supplied in PBS buffer, pH 7.5 with 0.05% NaN3
 Concentration    10.2 mg/ml (lot specific)
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 Immunogen    Purified natural CEA
 Affinity Constant    ~5.0 x 1010 L/M
 Biological Significance    Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
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 Preparation and Storage    Store at 4C
 Other Notes    Small volumes of anti-CEA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CEA antibody

   Mouse monoclonal CEA antibody
 Product Categories/Family for anti-CEA antibody    Cancer
 Applications Tested/Suitable for anti-CEA antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for CEA. It may not necessarily be applicable to this product.
 NCBI GI #    553222
 NCBI GeneID    4680
 NCBI Accession #    AAA51971.1 [Other Products]
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 UniProt Secondary Accession #    Q13774; Q14920; Q53XP7 [Other Products]
 UniProt Related Accession #    P40199 [Other Products]
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 NCBI Official Full Name    carcinoembryonic antigen, partial
 NCBI Official Synonym Full Names    carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
 NCBI Official Symbol    CEACAM6 [Similar Products]
 NCBI Official Synonym Symbols   
NCA; CEAL; CD66c
[Similar Products]
 NCBI Protein Information    carcinoembryonic antigen-related cell adhesion molecule 6
 UniProt Protein Name    Carcinoembryonic antigen-related cell adhesion molecule 6
 UniProt Synonym Protein Names   
Non-specific crossreacting antigen; Normal cross-reacting antigen; CD_antigen: CD66c
 Protein Family    Colicin
 UniProt Gene Name    CEACAM6 [Similar Products]
 UniProt Synonym Gene Names    NCA [Similar Products]
 UniProt Entry Name    CEAM6_HUMAN
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 NCBI Summary for CEA    This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
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 UniProt Comments for CEA    CEACAM6: Belongs to the immunoglobulin superfamily. CEA family

Protein type: Membrane protein, integral; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: cell-cell signaling; signal transduction; blood coagulation; leukocyte migration
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 Research Articles on CEA    1. CEACAM6 may be a valuable biomarker screening for gastric tumor and novel predictor for patients in advanced stages of gastric cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CEA antibodyPathways associated with anti-CEA antibody
 Reference Product  PubMed Publications
 CEACAM1 antibody  >54 publications with CEA and CEACAM1
 CEACAM8 antibody  >19 publications with CEA and CEACAM8
 SRC antibody  >12 publications with CEA and SRC
 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Fibronectin Matrix Formation Pathway antibodies  Fibronectin Matrix Formation Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-CEA antibodyOrgans/Tissues associated with anti-CEA antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >44 publications with CEA and Carcinoma
 Adenocarcinoma Antibodies  >36 publications with CEA and Adenocarcinoma
 Inflammation Antibodies  >21 publications with CEA and Inflammation
 Leukemia Antibodies  >17 publications with CEA and Leukemia
 Breast Neoplasms Antibodies  >14 publications with CEA and Breast Neoplasms
 Lung Neoplasms Antibodies  >12 publications with CEA and Lung Neoplasms
 Lymphoma Antibodies  >12 publications with CEA and Lymphoma
 Necrosis Antibodies  >7 publications with CEA and Necrosis
 Neoplasms, Experimental Antibodies  >6 publications with CEA and Neoplasms, Experimental
 Carcinoma, Squamous Cell Antibodies  >5 publications with CEA and Carcinoma, Squamous Cell
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >35 publications with CEA and Blood
 Intestine Antibodies  >31 publications with CEA and Intestine
 Lung Antibodies  >25 publications with CEA and Lung
 Stomach Antibodies  >11 publications with CEA and Stomach
 Bone Marrow Antibodies  >5 publications with CEA and Bone Marrow
 Pancreas Antibodies  >4 publications with CEA and Pancreas
 Prostate Antibodies  >3 publications with CEA and Prostate
 Skin Antibodies  >3 publications with CEA and Skin
 Bladder Antibodies  >3 publications with CEA and Bladder
 Trachea Antibodies  >1 publications with CEA and Trachea
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