View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-CFD antibody :: Rabbit anti-Mouse CFD Monoclonal Antibody Catalog # MBS2544605 Unit / Price 0.06 mL / $260 +1 FREE 8GB USB 0.12 mL / $380 +1 FREE 8GB USB 0.2 mL / $560 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CFD, Monoclonal Antibody Full Product Name Rabbit anti Mouse CFD Monoclonal Antibody Product Gene Name anti-CFD antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM AJ313463 mRNA Clonality Monoclonal Isotype IgG Host Rabbit Species Reactivity Mouse Immunogen Recombinant Mouse Adipsin/Complement Factor D/CFD protein Buffer 0.2 mum filtered solution in PBS with 5% trehalose Preparation and Storage This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-CFD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-CFD antibody Mouse complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to the peptidase S1 family. CFD/Adipsin contains one peptidase S1 domain. Complement factor D (CFD/Adipsin) is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Complement factor D (CFD/Adipsin) has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Complement factor D (CFD/Adipsin) cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D (CFD/Adipsin) is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD/Adipsin are the cause of complement factor D deficiency (CFD deficiency) which predisposes to invasive meningococcal disease. Applications Tested/Suitable for anti-CFD antibody Western Blot (WB) Application Notes for anti-CFD antibody WB: 2-10 mug/mL TOP NCBI/Uniprot data below describe general gene information for CFD. It may not necessarily be applicable to this product. NCBI GI # 55249559 NCBI GeneID 1675 UniProt Secondary Accession # Q5U5S1; Q86VJ5; Q8N4E0; Q8WZB4; B4DV76[Other Products] UniProt Related Accession # P00746[Other Products] Molecular Weight 27,033 Da TOP NCBI Official Full Name CFD protein, partial NCBI Official Synonym Full Names complement factor D NCBI Official Symbol CFD [Similar Products] NCBI Official Synonym Symbols DF; ADN; PFD; ADIPSIN [Similar Products] NCBI Protein Information complement factor D UniProt Protein Name Complement factor D UniProt Synonym Protein Names Adipsin; C3 convertase activator; Properdin factor D Protein Family Complement factor UniProt Gene Name CFD [Similar Products] UniProt Synonym Gene Names DF; PFD [Similar Products] UniProt Entry Name CFAD_HUMAN TOP NCBI Summary for CFD This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] TOP UniProt Comments for CFD Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Research Articles on CFD 1. our findings set up a novel mechanism for FABP4, adipsin and adiponectin through gut microbiota mediating expression in gut Paneth cells. 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TOP Products associated with anti-CFD antibody Reference Product PubMed Publications SPARC antibody >1 publications with CFD and SPARC INS antibody >1 publications with CFD and INS SERPING1 antibody >1 publications with CFD and SERPING1 SERPINE1 antibody >1 publications with CFD and SERPINE1 Pathways associated with anti-CFD antibody Products by Pathway Pathway Diagram Adipogenesis Pathway antibodies Adipogenesis Pathway Diagram Alternative Complement Activation Pathway antibodies Alternative Complement Activation Pathway Diagram Complement Activation Pathway antibodies Complement Activation Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement Cascade Pathway antibodies Complement Cascade Pathway Diagram Hemostasis Pathway antibodies Hemostasis Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Initial Triggering Of Complement Pathway antibodies Initial Triggering Of Complement Pathway Diagram Diseases associated with anti-CFD antibody Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >510 publications with CFD and Cardiovascular Diseases Heart Diseases Antibodies >149 publications with CFD and Heart Diseases Heart Failure Antibodies >56 publications with CFD and Heart Failure Hyperplasia Antibodies >35 publications with CFD and Hyperplasia Disease Models, Animal Antibodies >27 publications with CFD and Disease Models, Animal Inflammation Antibodies >25 publications with CFD and Inflammation Carcinoma Antibodies >22 publications with CFD and Carcinoma Hypertension Antibodies >19 publications with CFD and Hypertension Liver Diseases Antibodies >17 publications with CFD and Liver Diseases Kidney Diseases Antibodies >11 publications with CFD and Kidney Diseases Organs/Tissues associated with anti-CFD antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >892 publications with CFD and Blood Vascular Antibodies >592 publications with CFD and Vascular Heart Antibodies >353 publications with CFD and Heart Lung Antibodies >139 publications with CFD and Lung Brain Antibodies >101 publications with CFD and Brain Bone Antibodies >84 publications with CFD and Bone Mouth Antibodies >65 publications with CFD and Mouth Liver Antibodies >40 publications with CFD and Liver Muscle Antibodies >37 publications with CFD and Muscle Pharynx Antibodies >33 publications with CFD and Pharynx TOP