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anti-CKMT1 antibody :: anti-Human, Mouse CKMT1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS475046
Western Blot (WB)
Unit / Price
0.1 mL  /  $335 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CKMT1, Monoclonal Antibody

★Popular Item★
 Also Known As   

Anti-CKMT1 Mouse mAb

 Product Synonym Names    Acidic type mitochondrial creatine kinase; CKMT; CKMT1; CKMT1A; CKMT1B; Creatine kinase mitochondrial 1 ubiquitous; Creatine kinase U type, mitochondrial; Creatine kinase ubiquitous mitochondrial; Creatine kinase, mitochondrial 1 (ubiquitous); Creatine kinase, mitochondrial 1A; Creatine kinase, mitochondrial 1B; Mia CK; U MtCK; Ubiquitous mitochondrial creatine kinase; UMTCK
 Product Gene Name   

anti-CKMT1 antibody

[Similar Products]
 Product Synonym Gene Name    ckmt1b; CKMT; CKMT1; UMTCK; CKMT1A [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    J04469 Genomic DNA
 3D Structure    ModBase 3D Structure for P12532
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    1A6-C7-G10
 Host    Mouse
Source: Human
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity Purified
 Form/Format    Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
 Concentration    1mg/ml (lot specific)
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 Immunogen    Purified recombinant human CKMT1 protein fragments expressed in E Coli.
 Sensitivity    This antibody detects endogenous levels of CKMT1 and does not cross-react with related proteins.
 Sequence Similarities    Belongs to the ATP:guanido phosphotransferase family. Contains 1 phosphagen kinase C-terminal domain. Contains 1 phosphagen kinase N-terminal domain.
 Subunit Structure    Exists as an octamer composed of four MTCK homodimers.
 Subcellular Location    Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
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 Other Notes    Small volumes of anti-CKMT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CKMT1 antibody

   Entrez Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
 Product Categories/Family for anti-CKMT1 antibody    Metabolism; Pathways and Processes; Metabolism processes; Apoptosis; Metabolism; Pathways and Processes; Metabolic signaling pathways; Energy transfer pathways; Energy Metabolism
 Applications Tested/Suitable for anti-CKMT1 antibody   

Western Blot (WB)

 Application Notes for anti-CKMT1 antibody    WB: 1:1000
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 Western Blot (WB) of anti-CKMT1 antibody    Western blot detection of CKMT1 in Mouse Colon, 293 and A431 cell lysates using CKMT1 mouse mAb (1:1000 diluted).Predicted band size:47KDa.Observed band size:47KDa.
anti-CKMT1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CKMT1. It may not necessarily be applicable to this product.
 NCBI GI #    66346730
 NCBI GeneID    548596
 NCBI Accession #    NP_001015001.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020990.3 [Other Products]
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 UniProt Primary Accession #    P12532 [Other Products]
 UniProt Secondary Accession #    Q0VAM3; Q32NF6; Q53FC4; B4DIT8; B7ZA09 [Other Products]
 UniProt Related Accession #    P12532 [Other Products]
 Molecular Weight    47
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 NCBI Official Full Name    creatine kinase U-type, mitochondrial isoform 1
 NCBI Official Synonym Full Names    creatine kinase, mitochondrial 1A
 NCBI Official Symbol    CKMT1A [Similar Products]
 NCBI Official Synonym Symbols   
CKMT1; U-MtCK; mia-CK
[Similar Products]
 NCBI Protein Information    creatine kinase U-type, mitochondrial
 UniProt Protein Name    Creatine kinase U-type, mitochondrial
 UniProt Synonym Protein Names   
Acidic-type mitochondrial creatine kinase; Mia-CK; Ubiquitous mitochondrial creatine kinase; U-MtCK
 Protein Family    Creatine kinase
 UniProt Gene Name    CKMT1A [Similar Products]
 UniProt Synonym Gene Names    CKMT; Mia-CK; U-MtCK [Similar Products]
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 NCBI Summary for CKMT1    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CKMT1    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
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 Research Articles on CKMT1    1. CKMT1 is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CKMT1 antibodyPathways associated with anti-CKMT1 antibody
 Reference Product  PubMed Publications
 CATSPER2 antibody  >1 publications with CKMT1 and CATSPER2
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
Diseases associated with anti-CKMT1 antibodyOrgans/Tissues associated with anti-CKMT1 antibody
 Disease Name  Pubmed Publications
 Anemia Antibodies  >1 publications with CKMT1 and Anemia
 Nervous System Diseases Antibodies  >1 publications with CKMT1 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with CKMT1 and Nerve
 Connective Tissue Antibodies  >1 publications with CKMT1 and Connective Tissue
 Adipose Tissue Antibodies  >1 publications with CKMT1 and Adipose Tissue
 Thyroid Antibodies  >1 publications with CKMT1 and Thyroid
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