Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow CRNKL1 rightarrow Monoclonal CRNKL1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • APG5 (ATG5) Antibody
 • Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF)... Recombinant Protein
 • Single subunit botrocetin Recombinant Protein
 • Transcription termination factor Rho Antibody
 • A-779 Peptide
 • CBP (CREBBP) Antibody
 • MLF1 Recombinant Protein
 • F-actin-capping protein subunit alpha (CAP1) Recombinant Protein
 • Agouti-Related Protein (AGRP) Recombinant Protein
 • ITGA5 Antibody
 • Cholera Toxin beta subunit Antibody
 • Testosterone (Testo) ELISA Kit
 • Insulin ELISA Kit
 • 5-methyltetrahydrofolate-ho mocysteine methyltransferase (MTR... ELISA Kit
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CRNKL1 antibody :: Mouse anti-Human CRNKL1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120182
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRNKL1, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human CRNKL1

 Product Synonym Names    Homo sapiens Crn, crooked neck-like 1 (Drosophila) (CRNKL1), mRNA; CRN; HCRN; MSTP021
 Product Gene Name   

anti-CRNKL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    610952
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2212C1a
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Concentration    100 ug/ml (1.0 ml) (lot specific)
Section Bar
 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
Section Bar
 Other Notes    Small volumes of anti-CRNKL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for anti-CRNKL1 antibody

   The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to pre-mRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing. [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-CRNKL1 antibody   

Dot Blot (DB), Immunocytochemistry (ICC)

Section Bar
 Quality Control of anti-CRNKL1 antibody    Western blot analysis of immunized recombinant protein, using anti-CRNKL1 monoclonal antibody.
anti-CRNKL1 antibody Quality Control image
Section Bar
 Quality Control #2 of anti-CRNKL1 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-CRNKL1 antibody Quality Control #2 image
Section Bar
 Immunocytochemistry (ICC) of anti-CRNKL1 antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CRNKL1 mAb. [Lot No. 2212C1a-1]
anti-CRNKL1 antibody Immunocytochemistry (ICC) (ICC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CRNKL1. It may not necessarily be applicable to this product.
 NCBI GI #    520975420
 NCBI GeneID    51340
 NCBI Accession #    NP_057736.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_016652 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8; A8K9T4 [Other Products]
 UniProt Related Accession #    Q9BZJ0 [Other Products]
 Molecular Weight    7,946 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens crooked neck pre-mRNA splicing factor 1 (CRNKL1), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    crooked neck pre-mRNA splicing factor 1
 NCBI Official Symbol    CRNKL1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    crooked neck-like protein 1; Crn, crooked neck-like 1; SYF3 pre-mRNA-splicing factor; crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1
 UniProt Protein Name    Crooked neck-like protein 1
 UniProt Synonym Protein Names   
Crooked neck homolog; hCrn
 Protein Family    Crooked neck-like protein
 UniProt Gene Name    CRNKL1 [Similar Products]
 UniProt Entry Name    CRNL1_HUMAN
Section Bar
 NCBI Summary for CRNKL1    The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]
Section Bar
 UniProt Comments for CRNKL1    CRNKL1: Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA processing; RNA splicing

Chromosomal Location of Human Ortholog: 20p11.2

Cellular Component: spliceosome; cytoplasm; nuclear speck

Molecular Function: protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; spliceosome assembly
Table BarTOPTable Bar
 Research Articles on CRNKL1    1. Observational study of gene-disease association. (HuGE Navigator)
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-CRNKL1 antibodyDiseases associated with anti-CRNKL1 antibody
 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome, 35S U5-snRNP Pathway antibodies  Spliceosome, 35S U5-snRNP Pathway Diagram
 Spliceosome, 35S U5-snRNP Pathway antibodies  Spliceosome, 35S U5-snRNP Pathway Diagram
 Disease Name  Pubmed Publications
 Aneuploidy Antibodies  >1 publications with CRNKL1 and Aneuploidy
Organs/Tissues associated with anti-CRNKL1 antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with CRNKL1 and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions