Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CTSL1  rightarrow Monoclonal CTSL1   rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • GLP1R-GLP-1R-GLP-1 Receptor Antibody
 • C Reactive Protein (CRP) Antibody
 • chromosome 19 open reading frame 29 opposite strand (C19orf2... ELISA Kit
 • TrkA Antibody
 • hyaluronan synthase 2 (HAS2) ELISA Kit
 • RAD51L2 Antibody
 • Eck, N-terminal His tag (EPHA2) Recombinant Protein
 • Cytokeratin-18 (KRT18) Recombinant Protein
 • CD1A Antibody
 • IL-16 Antibody
 • Granulocyte Colony Stimulating Factor (G-CSF) ELISA Kit
 • Period Clock Protein Antibody
 • SSB IgG ELISA Kit
 • Human kappa light Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CTSL1  antibody :: Rabbit anti-Human CTSL1  Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2544011 anti-CTSL1  antibody
Unit / Price
0.06 mL  /  $215 +1 FREE 8GB USB
0.12 mL  /  $330 +1 FREE 8GB USB
0.2 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CTSL1 , Monoclonal Antibody

 Also Known As   

Rabbit anti Human CTSL1  Monoclonal Antibody

 Product Gene Name   

anti-CTSL1  antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Clonality    Monoclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
Section Bar
 Immunogen    Recombinant Human Cathepsin L/CTSL/CTSL1 protein
 Buffer    0.2 mum filtered solution in PBS with 5% trehalose
Section Bar
 Preparation and Storage    This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-CTSL1  antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-CTSL1  antibody

   Cathepsin L is a lysosomal cysteine protease that plays a major role in intracellular protein catabolism, and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural proteins of basement membranes. It is secreted by liver flukes at all stages of their development in the mammalian host, are believed to play important roles in facilitating parasite migration (tissue degradation), feeding and immuno-evasion. Like many proteases, Cathepsin L is synthesized as an inactive preproenzyme, and cleavage of the 96-residue proregion is necessary to generate the fully active 221-residue mature enzyme. Studies have demonstrated that cleavage of the proregion occur autocatalytically under acidic conditions. The enzyme takes part in nutrient acquisition by catabolizing host proteins to absorbable peptides, facilitates the migration of the parasite through the host intestine and liver by cleaving interstitial matrix proteins such as fibronectin, laminin and native collagen and is implicated in the inactivation of host immune defenses by cleaving immunoglobulins. Recently, Cathepsin L has been shown to suppress Th1 immune response in infected laboratory animals making them susceptible to concurrent bacterial infections. Cathepsin L is synthesized in large amounts and secreted by many malignantly transformed cells, and induced by growth factors and tumor promoters. In addition to its role in protein degradation, evidence has accumulated for the participation of Cathepsin L in various physiological and pathological processes, such as tumor invasion and metastasis, bone resorption, spermatogenesis, and arthritis. Accordingly, Cathepsin L may prove useful as a diagnostic or prognostic marker of human tumor malignancy.
 Applications Tested/Suitable for anti-CTSL1  antibody   

Western Blot (WB)

 Application Notes for anti-CTSL1  antibody    WB: 1-2 mug/mL
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CTSL1 . It may not necessarily be applicable to this product.
 NCBI GI #    47522698
 NCBI GeneID    396926
 NCBI GenBank Nucleotide #    NM_213892.1 [Other Products]
Section Bar
 UniProt Related Accession #    Q28944 [Other Products]
 Molecular Weight    37,178 Da
Table BarTOPTable Bar
 NCBI Official Full Name    cathepsin L1
 NCBI Official Symbol    CTSV [Similar Products]
 NCBI Official Synonym Symbols   
CTSL; CTSL1; CTSL2
[Similar Products]
 NCBI Protein Information    cathepsin L1
 UniProt Protein Name    Cathepsin L1
 UniProt Synonym Protein Names   
Cathepsin L
 UniProt Gene Name    CTSL [Similar Products]
 UniProt Synonym Gene Names    CTSL1 [Similar Products]
 UniProt Entry Name    CATL1_PIG
Section Bar
 UniProt Comments for CTSL1     Important for the overall degradation of proteins in lysosomes.
Table BarTOPTable Bar
 Research Articles on CTSL1     1. Endosomal acidification and cathepsin L activity is required for porcine enteric calicivirus replication.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CTSL1  antibodyPathways associated with anti-CTSL1  antibody
 Reference Product  PubMed Publications
 CTSL1 antibody  >1 publications with CTSL1  and CTSL1
 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Degradation Pathway antibodies  Collagen Degradation Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
Diseases associated with anti-CTSL1  antibodyOrgans/Tissues associated with anti-CTSL1  antibody
 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >1 publications with CTSL1  and Vascular Diseases
 Kidney Diseases Antibodies  >1 publications with CTSL1  and Kidney Diseases
 Fibrosis Antibodies  >1 publications with CTSL1  and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >4 publications with CTSL1  and Skin
 Bladder Antibodies  >1 publications with CTSL1  and Bladder
 Thymus Antibodies  >1 publications with CTSL1  and Thymus
 Muscle Antibodies  >1 publications with CTSL1  and Muscle
 Kidney Antibodies  >1 publications with CTSL1  and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions