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anti-CALB1 antibody :: Mouse Calbindin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS531456 anti-CALB1 antibody
Unit / Price
0.2 mL  /  $625 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calbindin (CALB1), Monoclonal Antibody

 Also Known As   

Calbindin antibody (D28K)

 Product Synonym Names    Monoclonal Calbindin (D28K); Anti-Calbindin (D28K); Calbindin D28; CALB1; CAB27; CALB 1; D 28K; Calbindin 1 28kDa; CALB; D28K; Neuronal Marker
 Product Gene Name   

anti-CALB1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    114050
 3D Structure    ModBase 3D Structure for P05937
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 Clonality    Monoclonal
 Clone Number    300
 Host    Mouse
 Species Reactivity    Chicken, Guinea Pig, Human, Monkey, Rabbit, Rat
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 Specificity    Chicken calbindin
 Form/Format    Supplied as a lyophilized powder.
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 Biological Significance    Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kDa protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity.
 Immunogen    Calbindin antibody (D28K) was raised in mouse using calbindin D-28k as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -80 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-CALB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CALB1 antibody

   Mouse monoclonal Calbindin antibody (D28K)
 Product Categories/Family for anti-CALB1 antibody    Nutrition & Metabolism
 Applications Tested/Suitable for anti-CALB1 antibody   

Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-CALB1 antibody    IHC: 1:2,000-1:5,000
WB: 1:1,000-1:2,000
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NCBI/Uniprot data below describe general gene information for CALB1. It may not necessarily be applicable to this product.
 NCBI GI #    4826655
 NCBI GeneID    793
 NCBI Accession #    NP_004920.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004929.2 [Other Products]
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 UniProt Primary Accession #    P05937 [Other Products]
 UniProt Secondary Accession #    B2R696; B7Z9J4 [Other Products]
 UniProt Related Accession #    P05937 [Other Products]
 Molecular Weight    23,609 Da [Similar Products]
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 NCBI Official Full Name    calbindin
 NCBI Official Synonym Full Names    calbindin 1, 28kDa
 NCBI Official Symbol    CALB1 [Similar Products]
 NCBI Official Synonym Symbols   
CALB; D-28K
[Similar Products]
 NCBI Protein Information    calbindin
 UniProt Protein Name    Calbindin
 UniProt Synonym Protein Names   
Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
 Protein Family    Calbindin
 UniProt Gene Name    CALB1 [Similar Products]
 UniProt Synonym Gene Names    CAB27 [Similar Products]
 UniProt Entry Name    CALB1_HUMAN
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 NCBI Summary for CALB1    The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015]
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 UniProt Comments for CALB1    CALB1: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Interacts with RANBP9. Belongs to the calbindin family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: cell soma; axon; dendrite; synapse; nucleus; cytosol

Molecular Function: vitamin D binding; protein binding; zinc ion binding; calcium ion binding

Biological Process: cytosolic calcium ion homeostasis; long-term memory; short-term memory; regulation of synaptic plasticity; locomotory behavior
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 Research Articles on CALB1    1. expressed by different neuron types, both inhibitory (GABAergic) and excitatory (glutamatergic), involved in both intrinsic and extrinsic circuits of the human cerebellar cortex
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CALB1 antibodyPathways associated with anti-CALB1 antibody
 Reference Product  PubMed Publications
 CA2 antibody  >107 publications with CALB1 and CA2
 S100G antibody  >42 publications with CALB1 and S100G
 TRPV5 antibody  >22 publications with CALB1 and TRPV5
 TRPV6 antibody  >11 publications with CALB1 and TRPV6
 CASP3 antibody  >10 publications with CALB1 and CASP3
 GDNF antibody  >4 publications with CALB1 and GDNF
 CA7 antibody  >1 publications with CALB1 and CA7
 Products by Pathway  Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
Diseases associated with anti-CALB1 antibodyOrgans/Tissues associated with anti-CALB1 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >115 publications with CALB1 and Nervous System Diseases
 Brain Diseases Antibodies  >94 publications with CALB1 and Brain Diseases
 Nerve Degeneration Antibodies  >47 publications with CALB1 and Nerve Degeneration
 Epilepsy Antibodies  >27 publications with CALB1 and Epilepsy
 Disease Models, Animal Antibodies  >24 publications with CALB1 and Disease Models, Animal
 Seizures Antibodies  >18 publications with CALB1 and Seizures
 Vascular Diseases Antibodies  >16 publications with CALB1 and Vascular Diseases
 Kidney Diseases Antibodies  >15 publications with CALB1 and Kidney Diseases
 Poisoning Antibodies  >11 publications with CALB1 and Poisoning
 Growth Disorders Antibodies  >10 publications with CALB1 and Growth Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >462 publications with CALB1 and Brain
 Kidney Antibodies  >100 publications with CALB1 and Kidney
 Blood Antibodies  >52 publications with CALB1 and Blood
 Embryonic Tissue Antibodies  >35 publications with CALB1 and Embryonic Tissue
 Muscle Antibodies  >23 publications with CALB1 and Muscle
 Eye Antibodies  >18 publications with CALB1 and Eye
 Lung Antibodies  >14 publications with CALB1 and Lung
 Connective Tissue Antibodies  >6 publications with CALB1 and Connective Tissue
 Stomach Antibodies  >5 publications with CALB1 and Stomach
 Ear Antibodies  >4 publications with CALB1 and Ear
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