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anti-CTNND1 antibody :: Mouse Catenin, delta 1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS607308 anti-CTNND1 antibody
Unit / Price
0.1 mg  /  $600 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Catenin, delta 1 (CTNND1), Monoclonal Antibody

 Also Known As   

Catenin, delta 1 (Cadherin-associated Src substrate, CAS, Catenin delta-1, CTNND, KIAA0384, p120, p120(cas), p120(ctn), p120cas, P120CAS, p120 Catenin, p120ctn, P120CTN)

 Product Synonym Names    Anti -Catenin, delta 1 (Cadherin-associated Src substrate, CAS, Catenin delta-1, CTNND, KIAA0384, p120, p120(cas), p120(ctn), p120cas, P120CAS, p120 Catenin, p120ctn, P120CTN)
 Product Gene Name   

anti-CTNND1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 11; NC_000011.9 (57529234..57586652). Location: 11q11
 3D Structure    ModBase 3D Structure for Q7KZJ3
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 Clonality    Monoclonal
 Isotype    IgG1k
 Clone Number    9H210
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes human p120 Catenin. Species Crossreactivity
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a liquid in 0.1M Tris-Glycine, pH7.4, 150mM sodium chloride.
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 Immunogen    Recombinant fusion protein derived from the C-terminus of murine p120. Cellular Localization: Cytoplasm. Nucleus. Cell membrane. Epitope: C-terminus.
 Positive Control    Hela cell lysate.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-CTNND1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CTNND1 antibody

   p120 Catenin is a cadherin-associated protein that binds intracellular proteins, such as the small GTPase, RhoA, and controls E-cadherin funcation and stability. Proteins of the p120 family and their isoforms are expressed in cells via alternative splicing, and all of them are essential for HGF signaling to Rac1.
 Product Categories/Family for anti-CTNND1 antibody    Antibodies; Abs to Catenin
 Applications Tested/Suitable for anti-CTNND1 antibody   

Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)

 Application Notes for anti-CTNND1 antibody    Suitable for use in Flow Cytometry, Western Blot and Immunocytochemistry.
Dilution: Western Blot: 1ug/ml detects p120 Catenin in lysate from Hela cells.
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NCBI/Uniprot data below describe general gene information for CTNND1. It may not necessarily be applicable to this product.
 NCBI GI #    119594195
 NCBI GeneID    1500
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 UniProt Primary Accession #    Q7KZJ3 [Other Products]
 UniProt Related Accession #    O60716; Q68DU0; Q7KZJ3; Q96FS1 [Other Products]
 Molecular Weight    68,003 Da [Similar Products]
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 NCBI Official Full Name    catenin (cadherin-associated protein), delta 1, isoform CRA_c
 NCBI Official Synonym Full Names    catenin (cadherin-associated protein), delta 1
 NCBI Official Symbol    CTNND1 [Similar Products]
 NCBI Official Synonym Symbols   
CAS; p120; CTNND; P120CAS; P120CTN; KIAA0384; p120(CAS); p120(CTN)
[Similar Products]
 NCBI Protein Information    catenin delta-1; p120 catenin; OTTHUMP00000235572; OTTHUMP00000235573; OTTHUMP00000235574; OTTHUMP00000235576; OTTHUMP00000235577; OTTHUMP00000235578; OTTHUMP00000235579; OTTHUMP00000235580; OTTHUMP00000235581; OTTHUMP00000235582; OTTHUMP00000235583; OTTHUMP00000235584; OTTHUMP00000235585; OTTHUMP00000235586; OTTHUMP00000235587; OTTHUMP00000235588; OTTHUMP00000235589; OTTHUMP00000235590; OTTHUMP00000235591; OTTHUMP00000235592; OTTHUMP00000235593; OTTHUMP00000235594; OTTHUMP00000235595; OTTHUMP00000235648; OTTHUMP00000235649; OTTHUMP00000235650; OTTHUMP00000235651; OTTHUMP00000235652; OTTHUMP00000235809; cadherin-associated Src substrate
 UniProt Protein Name    Catenin (Cadherin-associated protein), delta 1
 Protein Family    Catenin
 UniProt Entry Name    Q7KZJ3_HUMAN
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 NCBI Summary for CTNND1    This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq]
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 UniProt Comments for CTNND1    CTNND1: an Arm repeat protein that interacts with varied components such as cadherin, small G proteins, kinases, and the Kaiso transcriptional repressor. A downstream modulator of Wnt/beta-catenin signaling pathway whose stability may be regulated downstream of Dsh. Required for the invasiveness of E-cadherin-deficient cells. A signal coordinator between cadherins and Rho-family GTPases to regulate cytoskeletal changes required during dendritic spine and synapse development. The association of catenins with cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Thirty two splice-variant isoforms have been described.

Protein type: G protein regulator, misc.; Motility/polarity/chemotaxis; Actin-binding; Adaptor/scaffold; Cell adhesion

Chromosomal Location of Human Ortholog: 11q11

Cellular Component: growth cone; lamellipodium; cytoplasm; plasma membrane; dendritic spine; synapse; midbody; intercellular junction; zonula adherens; cytosol; nucleus

Molecular Function: protein binding; cadherin binding; protein kinase binding; receptor binding

Biological Process: intercellular junction assembly and maintenance; cell-cell adhesion; Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; brain development; vascular endothelial growth factor receptor signaling pathway; cell adhesion
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 Research Articles on CTNND1    1. the TGF-beta and p120-associated noncanonical beta-catenin pathways are important in pelvic lymph node metastasis in early-stage cervical cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CTNND1 antibodyDiseases associated with anti-CTNND1 antibody
 Products by Pathway  Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 E-cadherin Signaling In Keratinocytes Pathway antibodies  E-cadherin Signaling In Keratinocytes Pathway Diagram
 E-cadherin Signaling In The Nascent Adherens Junction Pathway antibodies  E-cadherin Signaling In The Nascent Adherens Junction Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with CTNND1 and Neoplasms
 Lung Neoplasms Antibodies  >2 publications with CTNND1 and Lung Neoplasms
 Lymphoma Antibodies  >1 publications with CTNND1 and Lymphoma
 Female Urogenital Diseases Antibodies  >1 publications with CTNND1 and Female Urogenital Diseases
 Carcinoma, Small Cell Antibodies  >1 publications with CTNND1 and Carcinoma, Small Cell
 Uterine Neoplasms Antibodies  >1 publications with CTNND1 and Uterine Neoplasms
 Death Antibodies  >1 publications with CTNND1 and Death
 Genital Neoplasms, Female Antibodies  >1 publications with CTNND1 and Genital Neoplasms, Female
 Uterine Diseases Antibodies  >1 publications with CTNND1 and Uterine Diseases
 Leukemia Antibodies  >1 publications with CTNND1 and Leukemia
Organs/Tissues associated with anti-CTNND1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with CTNND1 and Blood
 Lung Antibodies  >2 publications with CTNND1 and Lung
 Lymph Antibodies  >1 publications with CTNND1 and Lymph
 Ovary Antibodies  >1 publications with CTNND1 and Ovary
 Connective Tissue Antibodies  >1 publications with CTNND1 and Connective Tissue
 Lymph Node Antibodies  >1 publications with CTNND1 and Lymph Node
 Adipose Tissue Antibodies  >1 publications with CTNND1 and Adipose Tissue
 Brain Antibodies  >1 publications with CTNND1 and Brain
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