NP_059042
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
voltage-dependent L-type calcium channel subunit beta-1
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, beta 1 subunit
NCBI Protein Information
voltage-dependent L-type calcium channel subunit beta-1; CAB1; calcium channel beta 1 subunit; brain calcium channel beta 1 subunit; calcium channel voltage-dependent subunit beta 1
UniProt Protein Name
Voltage-dependent L-type calcium channel subunit beta-1
UniProt Synonym Protein Names
Calcium channel voltage-dependent subunit beta 1
UniProt Synonym Gene Names
UniProt Entry Name
CACB1_RAT
NCBI Summary for Cacnb1
may act as a regulatory component of a neuronal calcium channel [RGD, Feb 2006]
UniProt Comments for Cacnb1
CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, calcium
Cellular Component: sarcoplasmic reticulum; cell; T-tubule; voltage-gated calcium channel complex; intracellular; sarcolemma
Molecular Function: voltage-gated calcium channel activity; protein domain specific binding; protein binding; high voltage-gated calcium channel activity; phosphoprotein binding; protein kinase binding
Biological Process: synaptic transmission; calcium ion transport; protein targeting to membrane; neuromuscular junction development
Product References and Citations for anti-Cacnb1 antibody
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Leyris J.P., et al. (2009) Faseb J. EPub.
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Products associated with anti-Cacnb1 antibody
Pathways associated with anti-Cacnb1 antibody
Diseases associated with anti-Cacnb1 antibody
Organs/Tissues associated with anti-Cacnb1 antibody
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