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anti-CDNF antibody :: Mouse anti-Human Cerebral Dopamine Neurotrophic Factor (CDNF) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2090604
Western Blot (WB)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $145 +1 FREE 8GB USB
0.1 mg  /  $185 +1 FREE 8GB USB
0.2 mg  /  $235 +1 FREE 8GB USB
1 mg  /  $535 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cerebral Dopamine Neurotrophic Factor (CDNF), Monoclonal Antibody

 Also Known As   

Monoclonal Antibody to Cerebral Dopamine Neurotrophic Factor (CDNF)

 Product Synonym Names    ARMETL1; ARMET-like protein 1; Conserved Dopamine Neurotrophic Factor; Arginine-Rich,Mutated In Early Stage Tumors-Like 1
 Product Gene Name   

anti-CDNF antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AK301259 mRNA
 3D Structure    ModBase 3D Structure for Q49AH0
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 Clonality    Monoclonal
 Isotype    IgG2a Kappa
 Clone Number    C5
 Host    Mouse
 Species Reactivity    Human
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 Specificity    The antibody is a mouse monoclonal antibody raised against CDNF. It has been selected for its ability to recognize CDNF in immunohistochemical staining and western blotting.
 Purity/Purification    Protein A + Protein G affinity chromatography
 Form/Format    Liquid
 Concentration    1mg/mL (lot specific)
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 Immunogen    Eukaryotic Cerebral Dopamine Neurotrophic Factor (CDNF)
 Buffer Formulation    0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-CDNF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CDNF antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

 Application Notes for anti-CDNF antibody    Western Blot: 0.5-5ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
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 Western Blot (WB) of anti-CDNF antibody    (Figure. Western Blot; Sample: Recombinant CDNF, Human.)
anti-CDNF antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CDNF. It may not necessarily be applicable to this product.
 NCBI GI #    82880674
 NCBI GeneID    441549
 NCBI Accession #    NP_001025125.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001029954.2 [Other Products]
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 UniProt Primary Accession #    Q49AH0 [Other Products]
 UniProt Secondary Accession #    A2RUU0; B4DVW3 [Other Products]
 UniProt Related Accession #    Q49AH0 [Other Products]
 Molecular Weight    9,806 Da
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 NCBI Official Full Name    cerebral dopamine neurotrophic factor
 NCBI Official Synonym Full Names    cerebral dopamine neurotrophic factor
 NCBI Official Symbol    CDNF [Similar Products]
 NCBI Official Synonym Symbols   
ARMETL1
[Similar Products]
 NCBI Protein Information    cerebral dopamine neurotrophic factor
 UniProt Protein Name    Cerebral dopamine neurotrophic factor
 UniProt Synonym Protein Names   
ARMET-like protein 1; Conserved dopamine neurotrophic factor
 Protein Family    Cerebral dopamine neurotrophic factor
 UniProt Gene Name    CDNF [Similar Products]
 UniProt Synonym Gene Names    ARMETL1 [Similar Products]
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 UniProt Comments for CDNF    ARMETL1: Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. Belongs to the ARMET family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: endoplasmic reticulum; extracellular space

Molecular Function: growth factor activity

Biological Process: neuron projection development
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 Research Articles on CDNF    1. The results showed that AAV8-CDNF administration significantly improved the motor function and increased the tyrosine hydroxylase (TH) levels in Parkinson's disease rats with mild lesions (2 weeks post lesion), but it had limited therapeutic effects in rats with severe lesions (5 weeks post lesion).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-CDNF antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >3 publications with CDNF and Embryonic Tissue
 Testis Antibodies  >1 publications with CDNF and Testis
 Connective Tissue Antibodies  >1 publications with CDNF and Connective Tissue
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