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anti-CKB antibody :: Host: Mouse anti-Human Creatine Kinase BB (CK-BB) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS311596 anti-CKB antibody
Unit / Price
1 mg  /  $320 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Creatine Kinase BB (CK-BB) (CKB), Monoclonal Antibody

★Popular Item★
 Also Known As   

MAb to CK-BB

 Product Synonym Names    Monoclonal Antibody to Human Creatine Kinase BB (CK-BB)
 Product Gene Name   

anti-CKB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 14; NC_000014.8 (103985996..103989170, complement). Location: 14q32
 OMIM    123280
 3D Structure    ModBase 3D Structure for P12277
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 Clonality    Monoclonal
 Isotype    IgG1, kappa
 Clone Number    027-11288
 Host    Host: Mouse
 Species Reactivity    Human
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 Specificity    Creatine Kinase BB (CK-BB)
Human CK-BB
 Purity/Purification    >90% pure (SDS-PAGE). Protein A chromatography
Product is 0.2um filtered.
 Form/Format    Purified, Liquid
 Concentration    4.92mg/ml (OD280nm, E^0.1% = 1.4) (lot specific)
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 Source    Ascites
 Immunogen    Source: Human Brain
 Affinity Constant    Not determined.
 Buffer    10mM Phosphate, pH 7.4 containing 150mM Sodium Chloride
 Preservative    0.05% Sodium Azide
 Important Note    Centrifuge before opening to ensure complete recovery of vial contents.
 Warnings    This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
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 Preparation and Storage    Short term (up to 7 days) store at 2 to 8 degree C. Long term, aliquot and store at -20 degree C. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freeze/thaw.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CKB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CKB antibody    Monoclonal Antibodies to Cardiac Markers
 Application Notes for anti-CKB antibody    Specific methodologies have not been tested using this product.
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NCBI/Uniprot data below describe general gene information for CKB. It may not necessarily be applicable to this product.
 NCBI GI #    125294
 NCBI GeneID    1152
 NCBI Accession #    P12277.1 [Other Products]
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 UniProt Primary Accession #    P12277 [Other Products]
 UniProt Secondary Accession #    Q2LE07; Q6FG40; Q9UC66; A8K236; B2R5R4 [Other Products]
 UniProt Related Accession #    P12277 [Other Products]
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 NCBI Official Full Name    Creatine kinase B-type
 NCBI Official Synonym Full Names    creatine kinase, brain
 NCBI Official Symbol    CKB [Similar Products]
 NCBI Official Synonym Symbols   
B-CK; CKBB
[Similar Products]
 NCBI Protein Information    creatine kinase B-type; creatine kinase-B; creatine kinase B chain
 UniProt Protein Name    Creatine kinase B-type
 UniProt Synonym Protein Names   
B-CK; Creatine kinase B chain
 Protein Family    Creatine kinase
 UniProt Gene Name    CKB [Similar Products]
 UniProt Synonym Gene Names    CKBB [Similar Products]
 UniProt Entry Name    KCRB_HUMAN
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 NCBI Summary for CKB    The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq]
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 UniProt Comments for CKB    Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Catalytic activity: ATP + creatine = ADP + phosphocreatine.

Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.

Subcellular location: Cytoplasm.

Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.
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 Research Articles on CKB    1. CKB was up-regulated in women older than 38 years, and its expression in cumulus cells was associated with embryo quality
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CKB antibodyPathways associated with anti-CKB antibody
 Reference Product  PubMed Publications
 CKM antibody  >11 publications with CKB and CKM
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Urea Cycle And Metabolism Of Amino Groups Pathway antibodies  Urea Cycle And Metabolism Of Amino Groups Pathway Diagram
 Creatine-phosphate Biosynthesis Pathway antibodies  Creatine-phosphate Biosynthesis Pathway Diagram
Diseases associated with anti-CKB antibodyOrgans/Tissues associated with anti-CKB antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >21 publications with CKB and Neoplasms
 Cardiovascular Diseases Antibodies  >8 publications with CKB and Cardiovascular Diseases
 Vascular Diseases Antibodies  >7 publications with CKB and Vascular Diseases
 Nervous System Diseases Antibodies  >7 publications with CKB and Nervous System Diseases
 Central Nervous System Diseases Antibodies  >6 publications with CKB and Central Nervous System Diseases
 Brain Neoplasms Antibodies  >5 publications with CKB and Brain Neoplasms
 Glioma Antibodies  >5 publications with CKB and Glioma
 Heart Diseases Antibodies  >5 publications with CKB and Heart Diseases
 Adenocarcinoma Antibodies  >5 publications with CKB and Adenocarcinoma
 Glioblastoma Antibodies  >4 publications with CKB and Glioblastoma
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >46 publications with CKB and Brain
 Blood Antibodies  >25 publications with CKB and Blood
 Muscle Antibodies  >15 publications with CKB and Muscle
 Uterus Antibodies  >12 publications with CKB and Uterus
 Heart Antibodies  >6 publications with CKB and Heart
 Bone Antibodies  >5 publications with CKB and Bone
 Liver Antibodies  >5 publications with CKB and Liver
 Lymph Node Antibodies  >4 publications with CKB and Lymph Node
 Lymph Antibodies  >4 publications with CKB and Lymph
 Nerve Antibodies  >4 publications with CKB and Nerve
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