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anti-CYP3A7 antibody :: Mouse anti-Human Cytochrome P450 3A7 (CYP3A7) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2091263 anti-CYP3A7 antibody
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $165 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $270 +1 FREE 8GB USB
1 mg  /  $645 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cytochrome P450 3A7 (CYP3A7), Monoclonal Antibody

 Also Known As   

Biotin-Linked Monoclonal Antibody to Cytochrome P450 3A7 (CYP3A7)

 Product Gene Name   

anti-CYP3A7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    D00408 mRNA
 3D Structure    ModBase 3D Structure for P24462
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 Clonality    Monoclonal
 Host    Mouse
 Species Reactivity    Human
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 Concentration    500ug/ml (lot specific)
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 Conjugation    Biotin
 Immunogen    Pro344~Asp497
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 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-CYP3A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CYP3A7 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

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NCBI/Uniprot data below describe general gene information for CYP3A7. It may not necessarily be applicable to this product.
 NCBI GI #    608788370
 NCBI GeneID    1551
 NCBI Accession #    NP_000756.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000765.4 [Other Products]
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 UniProt Primary Accession #    P24462 [Other Products]
 UniProt Secondary Accession #    Q9H241; A4D288 [Other Products]
 UniProt Related Accession #    P24462 [Other Products]
 Molecular Weight    61,547 Da
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 NCBI Official Full Name    cytochrome P450 3A7
 NCBI Official Synonym Full Names    cytochrome P450 family 3 subfamily A member 7
 NCBI Official Symbol    CYP3A7 [Similar Products]
 NCBI Official Synonym Symbols   
CP37; CYPIIIA7; P450-HFLA; P-450111A7; P-450(HFL33)
[Similar Products]
 NCBI Protein Information    cytochrome P450 3A7
 UniProt Protein Name    Cytochrome P450 3A7
 UniProt Synonym Protein Names   
CYPIIIA7; Cytochrome P450-HFLA
 Protein Family    Cytochrome
 UniProt Gene Name    CYP3A7 [Similar Products]
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 NCBI Summary for CYP3A7    This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015]
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 UniProt Comments for CYP3A7    CYP3A7: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family.

Protein type: Cofactor and Vitamin Metabolism - retinol; EC; Lipid Metabolism - linoleic acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: heme binding; iron ion binding; monooxygenase activity; oxygen binding; steroid hydroxylase activity

Biological Process: steroid metabolic process; xenobiotic metabolic process
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 Research Articles on CYP3A7    1. All three neonicotinoid pesticides induced the expression of CYP3A7 in H295R cells; induction was reversed by co-treatment of H295R cells with exogenous estriol. CYP3A7 is normally expressed in fetal liver and is a key enzyme involved in estriol synthesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CYP3A7 antibodyPathways associated with anti-CYP3A7 antibody
 Reference Product  PubMed Publications
 CYP1A2 antibody  >44 publications with CYP3A7 and CYP1A2
 CYP2D6 antibody  >31 publications with CYP3A7 and CYP2D6
 CYP2C9 antibody  >30 publications with CYP3A7 and CYP2C9
 CYP2C8 antibody  >23 publications with CYP3A7 and CYP2C8
 CYP2B6 antibody  >20 publications with CYP3A7 and CYP2B6
 CYP2C19 antibody  >18 publications with CYP3A7 and CYP2C19
 CYP2A6 antibody  >15 publications with CYP3A7 and CYP2A6
 UGT1A1 antibody  >7 publications with CYP3A7 and UGT1A1
 UGT2B7 antibody  >5 publications with CYP3A7 and UGT2B7
 UGT1A6 antibody  >4 publications with CYP3A7 and UGT1A6
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
Organs/Tissues associated with anti-CYP3A7 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >152 publications with CYP3A7 and Liver
 Blood Antibodies  >31 publications with CYP3A7 and Blood
 Kidney Antibodies  >23 publications with CYP3A7 and Kidney
 Embryonic Tissue Antibodies  >18 publications with CYP3A7 and Embryonic Tissue
 Placenta Antibodies  >11 publications with CYP3A7 and Placenta
 Heart Antibodies  >5 publications with CYP3A7 and Heart
 Connective Tissue Antibodies  >2 publications with CYP3A7 and Connective Tissue
 Spleen Antibodies  >1 publications with CYP3A7 and Spleen
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