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anti-CAMK2A antibody :: Mouse anti-Human Cytokeratin 8,18,19 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS609881 anti-CAMK2A antibody
Unit / Price
0.1 mg  /  $730 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cytokeratin 8,18,19 (CAMK2A), Monoclonal Antibody

 Also Known As   

Cytokeratin 8,18,19 (Cytokeratin 8, Cytokeratin-8, CK 8, CK8, CK-8, Cyk8, Cytokeratin 18, Cytokeratin-18, CK 18, CK18, CK-18, CYK18, Cytokeratin 19, Cytokeratin-19, CK 19, CK19, CK-19)

 Product Synonym Names    Anti -Cytokeratin 8,18,19 (Cytokeratin 8, Cytokeratin-8, CK 8, CK8, CK-8, Cyk8, Cytokeratin 18, Cytokeratin-18, CK 18, CK18, CK-18, CYK18, Cytokeratin 19, Cytokeratin-19, CK 19, CK19, CK-19)
 Product Gene Name   

anti-CAMK2A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_000005.9 (149599054..149669403, complement). Location: 5q32
 OMIM    114078
 3D Structure    ModBase 3D Structure for Q9UQM7
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2A4
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognizes human cytokeratin 8, 18 and 19. Typical for simple epithelial cells.
 Purity/Purification    Ascites
Serum
 Form/Format    Supplied as a liquid in PBS, 1% BSA, 0.1% sodium azide.
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 Immunogen    Cytokeratins isolated from cultured pig kidney epithelial cells
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
 Other Notes    Small volumes of anti-CAMK2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CAMK2A antibody

   The cytoplasmic cytoskeleton determines cell organization, shape and adhesion among other functions. Furthermore, the cell type-specific expression of intermediate filaments allows determination of the origin of many, otherwise unspecific tumors.
 Product Categories/Family for anti-CAMK2A antibody    Antibodies; Abs to Cytokeratin
 Applications Tested/Suitable for anti-CAMK2A antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CAMK2A antibody    Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:1000
Immunohistochemistry: Frozen
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NCBI/Uniprot data below describe general gene information for CAMK2A. It may not necessarily be applicable to this product.
 NCBI GI #    25952118
 NCBI GeneID    815
 NCBI Accession #    NP_741960.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_171825.2 [Other Products]
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 UniProt Primary Accession #    Q9UQM7 [Other Products]
 UniProt Secondary Accession #    Q9UL21; Q9Y2H4; Q9Y352 [Other Products]
 UniProt Related Accession #    Q9UQM7 [Other Products]
 Molecular Weight    54,088 Da [Similar Products]
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 NCBI Official Full Name    calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2
 NCBI Official Synonym Full Names    calcium/calmodulin-dependent protein kinase II alpha
 NCBI Official Symbol    CAMK2A [Similar Products]
 NCBI Official Synonym Symbols   
CAMKA
[Similar Products]
 NCBI Protein Information    calcium/calmodulin-dependent protein kinase type II subunit alpha; CaMKIINalpha; CaMK-II alpha subunit; caMK-II subunit alpha; CaM-kinase II alpha chain; CaM kinase II alpha subunit; caM kinase II subunit alpha; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
 UniProt Protein Name    Calcium/calmodulin-dependent protein kinase type II subunit alpha
 Protein Family    Calcium/calmodulin-dependent protein kinase
 UniProt Gene Name    CAMK2A [Similar Products]
 UniProt Synonym Gene Names    CAMKA; KIAA0968; CaM kinase II subunit alpha [Similar Products]
 UniProt Entry Name    KCC2A_HUMAN
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 NCBI Summary for CAMK2A    The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
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 UniProt Comments for CAMK2A    CAMK2A: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.11.17; Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CAMK group; CAMK2 family

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: presynaptic membrane; nucleoplasm; mitochondrion; plasma membrane; cytosol; cell junction; nucleus

Molecular Function: calmodulin binding; protein serine/threonine kinase activity; protein binding; glutamate receptor binding; protein homodimerization activity; calmodulin-dependent protein kinase activity; kinase activity; ATP binding

Biological Process: synaptic transmission; peptidyl-serine phosphorylation; cytokine and chemokine mediated signaling pathway; protein amino acid autophosphorylation; calcium ion transport; regulation of neurotransmitter secretion; positive regulation of calcium ion transport; protein amino acid phosphorylation; activation of NF-kappaB transcription factor; regulation of neuronal synaptic plasticity; G1/S transition of mitotic cell cycle
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 Research Articles on CAMK2A    1. These results suggest that Osterix is a novel target of CaMKII and the activity of Osterix can be modulated by a novel mechanism involving CaMKII during osteoblast differentiation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CAMK2A antibodyPathways associated with anti-CAMK2A antibody
 Reference Product  PubMed Publications
 CAMK2B antibody  >6 publications with CAMK2A and CAMK2B
 CREB1 antibody  >1 publications with CAMK2A and CREB1
 GRIN2A antibody  >1 publications with CAMK2A and GRIN2A
 GRIN2B antibody  >1 publications with CAMK2A and GRIN2B
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 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
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 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
Diseases associated with anti-CAMK2A antibodyOrgans/Tissues associated with anti-CAMK2A antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >43 publications with CAMK2A and Nervous System Diseases
 Brain Diseases Antibodies  >27 publications with CAMK2A and Brain Diseases
 Pain Antibodies  >8 publications with CAMK2A and Pain
 Seizures Antibodies  >6 publications with CAMK2A and Seizures
 Movement Disorders Antibodies  >5 publications with CAMK2A and Movement Disorders
 Cognition Disorders Antibodies  >4 publications with CAMK2A and Cognition Disorders
 Memory Disorders Antibodies  >4 publications with CAMK2A and Memory Disorders
 Learning Disorders Antibodies  >4 publications with CAMK2A and Learning Disorders
 Inflammation Antibodies  >4 publications with CAMK2A and Inflammation
 Nerve Degeneration Antibodies  >3 publications with CAMK2A and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >124 publications with CAMK2A and Brain
 Muscle Antibodies  >5 publications with CAMK2A and Muscle
 Eye Antibodies  >4 publications with CAMK2A and Eye
 Embryonic Tissue Antibodies  >4 publications with CAMK2A and Embryonic Tissue
 Kidney Antibodies  >4 publications with CAMK2A and Kidney
 Heart Antibodies  >3 publications with CAMK2A and Heart
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