View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List D-Dimer Monoclonal Antibody Catalog # MBS660086 Unit / Price 1 mg / $700 +1 FREE 8GB USB 5 mg / $2,695 +3 FREE 8GB USB 10 mg / $4,980 +6 FREE 8GB USB 15 mg / $6,990 +8 FREE 8GB USB 25 mg / $11,070 +10 FREE 8GB USB 50 mg / $20,460 +10 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name D-Dimer, Monoclonal Antibody Full Product Name Monoclonal mouse anti-D-dimer Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG1 for MAbs DD93, DD189, DD255IgG2a for MAbs DD1, DD6, DD22, DD41, DD46IgG2b for MAbs DD2, DD3, DD4, DD5, DD44. Clone Number New MAbs: DD189, DD255 Specificity All MAbs recognize D-dimer and high molecular weight fibrin degradation products.MAb DD93 recognizes a cross-linked region of D-dimer.MAbs DD1, DD2, DD3, DD22, DD41, DD44, DD46, DD93, DD189 and DD255 do not cross-react with fibrinogen.MAbs DD4, DD5 and DD6 show cross-reaction with fibrinogen. Purity/Purification Chromatography on protein A Sepharose Form/Format PBS, pH 7.4, 0.1 % sodium azide (NaN3) Clone Note DD1, DD2, DD3, DD4, DD5, DD6, DD22, DD41, DD44, DD46, DD93Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot, D-dimer or high molecular weight fibrin degradation products. Preparation and Storage 4 degree C Other Notes Small volumes of anti-D-Dimer antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Applications Tested/Suitable for anti-D-Dimer antibody ELISA (EIA), Western Blot (WB) Application Notes for anti-D-Dimer antibody Immunoassays for the quantitative determination of D-dimer and high molecular weight fibrin degradation products.All antibodies recognize D-dimer in ELISA. All MAbs recognize D-dimer in Western blotting under non-reducing conditions. MAbs DD22, DD41, DD44, DD46 and DD189 interact with beta-chain of D-dimer in Western blotting under reducing conditions. MAbs DD93 and DD255 interact with gamma-chain of D-dimer in Western blotting under reducing conditions.Recommended pairs to be used in a sandwich immunoassay for D-dimer detection in human plasma (capture-detection):One-step sandwich immunoassays:DD189 - DD255 (Equal specificity to D-dimer and high MW fibrin degradation products). DD2 - DD41 (Slightly more specific to high MW fibrin degradation products at high concentrations).Two-step sandwich immunoassays*:DD2 - DD4 (Approximately equal specificity to D-dimer and high MW fibrin degradation products).(*To be analyzed in a two-step sandwich immunoassay, plasma must be diluted 1:1 or more with 10 mM Tris-HCl buffer, pH 7.5, containing 1 M NaCl and 0.1 % Tween 20. To avoid non-specific binding the final NaCl concentration in plasma samples must be 0.5 M or more.) TOP Product References and Citations for anti-D-Dimer antibody Search D-dimer antibody references from PubMed TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP