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anti-DBF4 antibody :: Mouse anti-Human DBF4 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120101
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DBF4, Monoclonal Antibody

★Popular Item★
 Also Known As   

Mouse monoclonal antibody Anti-Human DBF4

 Product Synonym Names    Homo sapiens DBF4 homolog (S. cerevisiae) (DBF4), mRNA; ASK; DBF4A
 Product Gene Name   

anti-DBF4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604281
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2047C4a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-DBF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DBF4 antibody

   Play a role as a regulatory subunit for CDC7 which activates its kinase activity. Is required for entry into S phase. The complex CDC7-DBF4 selectively phosphorylates MCM2 subunit of chromatin-associated MCM complex and then is involved in regulating the initiation of DNA replication during cell cycle{EC1,EC2}. [UniProtKB Function]
 Applications Tested/Suitable for anti-DBF4 antibody   

Dot Blot (DB)

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 Quality Control of anti-DBF4 antibody    Western blot analysis of immunized recombinant protein, using anti-DBF4 monoclonal antibody.
anti-DBF4 antibody Quality Control image
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 Quality Control #2 of anti-DBF4 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-DBF4 antibody Quality Control #2 image
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NCBI/Uniprot data below describe general gene information for DBF4. It may not necessarily be applicable to this product.
 NCBI GI #    41393589
 NCBI GeneID    10926
 NCBI Accession #    NP_006707.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006716 [Other Products]
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 UniProt Secondary Accession #    O75226; Q75MS6; Q75N01; Q9Y2M6; A4D1D8; A8K954 [Other Products]
 UniProt Related Accession #    Q9UBU7 [Other Products]
 Molecular Weight    26,124 Da
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 NCBI Official Full Name    Homo sapiens DBF4 zinc finger (DBF4), mRNA
 NCBI Official Synonym Full Names    DBF4 zinc finger
 NCBI Official Symbol    DBF4 [Similar Products]
 NCBI Official Synonym Symbols   
ASK; CHIF; DBF4A; ZDBF1
[Similar Products]
 NCBI Protein Information    protein DBF4 homolog A; DBF4 zinc finger A; DBF4-type zinc finger-containing protein 1; activator of S phase kinase; chiffon homolog A; zinc finger, DBF-type containing 1
 UniProt Protein Name    Protein DBF4 homolog A
 UniProt Synonym Protein Names   
Activator of S phase kinase; Chiffon homolog A; DBF4-type zinc finger-containing protein 1
 Protein Family    DDK kinase regulatory
 UniProt Gene Name    DBF4 [Similar Products]
 UniProt Entry Name    DBF4A_HUMAN
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 UniProt Comments for DBF4    DBF4: DBF4

Protein type: Protein kinase, regulatory subunit; Cell cycle regulation

Chromosomal Location of Human Ortholog: 7q21.3

Cellular Component: nucleoplasm

Molecular Function: nucleic acid binding; zinc ion binding; enzyme activator activity

Biological Process: positive regulation of catalytic activity; mitotic cell cycle; DNA replication; G1/S transition of mitotic cell cycle
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 Research Articles on DBF4    1. The anti-invasive and cell cycle arrest-inducing effects of nitrogen-containing bisphosphonates are not DBF4 mediated in human breast cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DBF4 antibodyPathways associated with anti-DBF4 antibody
 Reference Product  PubMed Publications
 CDC7 antibody  >168 publications with DBF4 and CDC7
 MCM2 antibody  >46 publications with DBF4 and MCM2
 CDC45 antibody  >26 publications with DBF4 and CDC45
 MCM4 antibody  >16 publications with DBF4 and MCM4
 MCM7 antibody  >11 publications with DBF4 and MCM7
 MCM3 antibody  >4 publications with DBF4 and MCM3
 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
Diseases associated with anti-DBF4 antibodyOrgans/Tissues associated with anti-DBF4 antibody
 Disease Name  Pubmed Publications
 Ataxia Antibodies  >9 publications with DBF4 and Ataxia
 Breast Neoplasms Antibodies  >3 publications with DBF4 and Breast Neoplasms
 Lung Neoplasms Antibodies  >2 publications with DBF4 and Lung Neoplasms
 Carcinoma Antibodies  >1 publications with DBF4 and Carcinoma
 Lung Diseases Antibodies  >1 publications with DBF4 and Lung Diseases
 Drug Hypersensitivity Antibodies  >1 publications with DBF4 and Drug Hypersensitivity
 Hypertension Antibodies  >1 publications with DBF4 and Hypertension
 Anemia Antibodies  >1 publications with DBF4 and Anemia
 Liver Diseases Antibodies  >1 publications with DBF4 and Liver Diseases
 Inflammation Antibodies  >1 publications with DBF4 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with DBF4 and Lung
 Eye Antibodies  >3 publications with DBF4 and Eye
 Ovary Antibodies  >2 publications with DBF4 and Ovary
 Embryonic Tissue Antibodies  >2 publications with DBF4 and Embryonic Tissue
 Skin Antibodies  >2 publications with DBF4 and Skin
 Bone Antibodies  >1 publications with DBF4 and Bone
 Blood Antibodies  >1 publications with DBF4 and Blood
 Kidney Antibodies  >1 publications with DBF4 and Kidney
 Muscle Antibodies  >1 publications with DBF4 and Muscle
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