NP_061947.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 74.6 kDa Predicted: 75 kDa
NCBI Official Full Name
delta-like protein 4
NCBI Official Synonym Full Names
delta like canonical Notch ligand 4
NCBI Protein Information
delta-like protein 4
UniProt Protein Name
Delta-like protein 4
UniProt Synonym Protein Names
Drosophila Delta homolog 4; Delta4
UniProt Synonym Gene Names
NCBI Summary for DLL4
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]
UniProt Comments for DLL4
Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).
Research Articles on DLL4
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Disclaimer
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Products associated with anti-DLL4 antibody
Pathways associated with anti-DLL4 antibody
Diseases associated with anti-DLL4 antibody
Organs/Tissues associated with anti-DLL4 antibody
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