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anti-DACT3 antibody :: Mouse Dapper homolog 3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS140243 anti-DACT3 antibody
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $505 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dapper homolog 3 (DACT3), Monoclonal Antibody

 Also Known As   

Mouse Anti Human Dapper homolog 3

 Product Synonym Names    DACT3 Antibody; Dapper homolog 3, Mouse Anti Human; Dapper homolog 3; Antagonist of beta-catenin Dapper homolog 3; Arginine-rich region 1 protein; DACT3; RRR1; MGC15476
 Product Gene Name   

anti-DACT3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611112
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 Clonality    Monoclonal
 Isotype    IgG1 heavy chain and kappa light chain
 Clone Number    P2A5AT
 Host    Mouse
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 Purity/Purification    DACT3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
 Form/Format    1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
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 Immunogen    Anti-human DACT3 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human DACT3 amino acids 89-202 purified from E Coli.
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 Preparation and Storage    For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
 Other Notes    Small volumes of anti-DACT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DACT3 antibody

   Introduction: DACT3 which belongs to the DACT (Dpr/Frodo) gene family plays an imperative role in a negative regulator of Wnt/-catenin signaling. Unlike other Wnt signaling inhibitors that are silenced by DNA methylation, DACT3 repression is linked to bivalent histone modifications.
 Product Categories/Family for anti-DACT3 antibody    MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
 Applications Tested/Suitable for anti-DACT3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-DACT3 antibody    DACT3 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:250 ~ 1:500 and immunohistochemistry analysis is 1:50. Recommended starting dilution for Western blot is 1:250 and Immunohistochemistry is 1:50.
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NCBI/Uniprot data below describe general gene information for DACT3. It may not necessarily be applicable to this product.
 NCBI GI #    119368655
 NCBI GeneID    147906
 NCBI Accession #    Q96B18.2 [Other Products]
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 UniProt Related Accession #    Q96B18 [Other Products]
 Molecular Weight    64,949 Da
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 NCBI Official Full Name    Dapper homolog 3
 NCBI Official Synonym Full Names    dishevelled-binding antagonist of beta-catenin 3
 NCBI Official Symbol    DACT3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    dapper homolog 3; antagonist of beta-catenin Dapper homolog 3; arginine-rich region 1 protein; dapper, antagonist of beta-catenin, homolog 3
 UniProt Protein Name    Dapper homolog 3
 UniProt Synonym Protein Names   
Antagonist of beta-catenin Dapper homolog 3; Arginine-rich region 1 protein; Dapper antagonist of catenin 3
 Protein Family    Dapper
 UniProt Gene Name    DACT3 [Similar Products]
 UniProt Synonym Gene Names    RRR1 [Similar Products]
 UniProt Entry Name    DACT3_HUMAN
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 UniProt Comments for DACT3    DACT3: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Belongs to the dapper family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytoplasm

Molecular Function: identical protein binding; protein kinase C binding; protein kinase A binding

Biological Process: Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; negative regulation of cell growth
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 Research Articles on DACT3    1. Epigenetic repression of DACT3 leads to aberrant Wnt-beta-catenin signaling in colorectal cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-DACT3 antibodyOrgans/Tissues associated with anti-DACT3 antibody
 Disease Name  Pubmed Publications
 Endocrine Gland Neoplasms Antibodies  >2 publications with DACT3 and Endocrine Gland Neoplasms
 Ovarian Neoplasms Antibodies  >1 publications with DACT3 and Ovarian Neoplasms
 Lung Diseases Antibodies  >1 publications with DACT3 and Lung Diseases
 Fibrosis Antibodies  >1 publications with DACT3 and Fibrosis
 Neoplasm Metastasis Antibodies  >1 publications with DACT3 and Neoplasm Metastasis
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >5 publications with DACT3 and Embryonic Tissue
 Kidney Antibodies  >2 publications with DACT3 and Kidney
 Heart Antibodies  >1 publications with DACT3 and Heart
 Lung Antibodies  >1 publications with DACT3 and Lung
 Thymus Antibodies  >1 publications with DACT3 and Thymus
 Brain Antibodies  >1 publications with DACT3 and Brain
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