BAA82958.1
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UniProt Secondary Accession #
Molecular Weight
30,380 Da
NCBI Official Full Name
EB3 protein
UniProt Protein Name
Microtubule-associated protein RP/EB family member 3
UniProt Synonym Protein Names
EB1 protein family member 3; EBF3; End-binding protein 3; EB3; RP3
UniProt Synonym Gene Names
UniProt Entry Name
MARE3_HUMAN
UniProt Comments for EB3
EB3: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. Belongs to the MAPRE family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding
Chromosomal Location of Human Ortholog: 2p23.3-p23.1
Cellular Component: microtubule cytoskeleton; cytoplasmic microtubule; perinuclear region of cytoplasm; cytoplasm; midbody
Molecular Function: protein binding; microtubule binding
Biological Process: mitosis; positive regulation of cyclin-dependent protein kinase activity; cell division; positive regulation of transcription, DNA-dependent
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