AAA50284.1
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UniProt Secondary Accession #
NCBI Official Full Name
eosinophil derived neurotoxin
UniProt Protein Name
Non-secretory ribonuclease
UniProt Synonym Protein Names
Eosinophil-derived neurotoxin; RNase UpI-2; Ribonuclease 2; RNase 2; Ribonuclease US
UniProt Synonym Gene Names
UniProt Entry Name
RNAS2_HUMAN
UniProt Comments for EDN
RNASE2: This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. Belongs to the pancreatic ribonuclease family.
Protein type: Motility/polarity/chemotaxis; Ribonuclease; RNA processing; EC 3.1.27.5
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: lysosome; extracellular region
Molecular Function: nucleic acid binding; pancreatic ribonuclease activity; ribonuclease activity
Biological Process: RNA catabolic process; chemotaxis
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