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anti-EPHX2 antibody :: Mouse anti-Human EPHX2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2542283 anti-EPHX2 antibody
Unit / Price
0.06 mL  /  $215 +1 FREE 8GB USB
0.12 mL  /  $330 +1 FREE 8GB USB
0.2 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EPHX2, Monoclonal Antibody

 Also Known As   

EPHX2 Antibody

 Product Synonym Names    CEH; Cytosolic epoxide hydrolase; EPHX2; Epoxide hydratase; Epoxide hydrolase 2; SEH; Soluble epoxide hydrolase
 Product Gene Name   

anti-EPHX2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    L05779 mRNA
 3D Structure    ModBase 3D Structure for P34913
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 Clonality    Monoclonal
 Isotype    IgG1
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Caprylic acid/ammonium sulfate precipitation
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 Immunogen    EPHX2 fusion protein ag4870
 Buffer    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-EPHX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-EPHX2 antibody

   EPHX2 (Epoxide hydrolase 2) acts on epoxides (alkene oxides, oxiranes) and arene oxides and plays a role in xenobiotic metabolism by degrading potentially toxic epoxides.It was observed in mant tissues with the band of 63KDa in the western blot.It has also been reported that the N-terminal domain might promote dimerization of EPHX2.
 Applications Tested/Suitable for anti-EPHX2 antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for EPHX2. It may not necessarily be applicable to this product.
 NCBI GI #    1359739
 NCBI GeneID    2053
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 UniProt Primary Accession #    P34913 [Other Products]
 UniProt Secondary Accession #    Q16764; Q9HBJ1; Q9HBJ2; B2Z3B1; B3KTU8; B3KUA0; G3V134; J3KPH7 [Other Products]
 UniProt Related Accession #    P34913 [Other Products]
 Molecular Weight    Calculated MW: 63 kDa
Observed MW: 63 kDa
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 NCBI Official Full Name    epoxide hydrolase
 NCBI Official Synonym Full Names    epoxide hydrolase 2
 NCBI Official Symbol    EPHX2 [Similar Products]
 NCBI Official Synonym Symbols   
CEH; SEH
[Similar Products]
 NCBI Protein Information    bifunctional epoxide hydrolase 2
 UniProt Protein Name    Bifunctional epoxide hydrolase 2
 UniProt Synonym Protein Names   
Cytosolic epoxide hydrolase 2 (EC:3.3.2.10); CEHAlternative name(s):Epoxide hydratase; Soluble epoxide hydrolase; SEH
 Protein Family    Bifunctional epoxide hydrolase
 UniProt Gene Name    EPHX2 [Similar Products]
 UniProt Synonym Gene Names    CEH; SEH [Similar Products]
 UniProt Entry Name    HYES_HUMAN
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 NCBI Summary for EPHX2    This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
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 UniProt Comments for EPHX2    EPHX2: Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo- 9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro- 9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy- octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate. Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.

Protein type: EC 3.1.3.76; EC 3.3.2.10; Hydrolase; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: cytoplasm; cytosol; peroxisome

Molecular Function: epoxide hydrolase activity; lipid phosphatase activity; magnesium ion binding; phosphoric monoester hydrolase activity; protein homodimerization activity; receptor binding; toxin binding

Biological Process: cholesterol homeostasis; dephosphorylation; epoxygenase P450 pathway; phospholipid dephosphorylation; stilbene catabolic process

Disease: Hypercholesterolemia, Familial
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 Research Articles on EPHX2    1. Increased levels of soluble epoxide hydrolase in the brain of depressed patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to EPHX2 Antibody
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 MBS7234059  Porcine Epoxide hydrolase 2 (EPHX2) ELISA Kit  MBS8245110  Anti-EPHX2 Antibody
 MBS423655  Goat anti-EPHX2 (aa238-251) Antibody  MBS7209470  Bovine Epoxide hydrolase 2 (EPHX2) ELISA Kit
 MBS7216736  Sheep Epoxide hydrolase 2 (EPHX2) ELISA Kit  MBS828879  EPHX2 siRNA (Rat)
 MBS243333  Rabbit Polyclonal to Human SEH / EPHX2  MBS961023  Recombinant Mouse Epoxide hydrolase 2 (Ephx2)
 MBS7000211  EPHX2 Antibody  MBS2542283  EPHX2 Antibody
Products associated with anti-EPHX2 antibodyPathways associated with anti-EPHX2 antibody
 Reference Product  PubMed Publications
 CYP2J2 antibody  >13 publications with EPHX2 and CYP2J2
 CYP1A1 antibody  >10 publications with EPHX2 and CYP1A1
 CYP1B1 antibody  >9 publications with EPHX2 and CYP1B1
 CYP2C8 antibody  >8 publications with EPHX2 and CYP2C8
 CYP2C9 antibody  >6 publications with EPHX2 and CYP2C9
 CYP1A2 antibody  >4 publications with EPHX2 and CYP1A2
 CYP2C19 antibody  >1 publications with EPHX2 and CYP2C19
 Products by Pathway  Pathway Diagram
 Arachidonate Epoxygenase / Epoxide Hydrolase Pathway antibodies  Arachidonate Epoxygenase / Epoxide Hydrolase Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metapathway Biotransformation antibodies  Metapathway Biotransformation Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
Diseases associated with anti-EPHX2 antibodyOrgans/Tissues associated with anti-EPHX2 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >85 publications with EPHX2 and Cardiovascular Diseases
 Hypertension Antibodies  >38 publications with EPHX2 and Hypertension
 Heart Diseases Antibodies  >35 publications with EPHX2 and Heart Diseases
 Inflammation Antibodies  >33 publications with EPHX2 and Inflammation
 Nervous System Diseases Antibodies  >28 publications with EPHX2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >28 publications with EPHX2 and Disease Models, Animal
 Hypertrophy Antibodies  >14 publications with EPHX2 and Hypertrophy
 Atherosclerosis Antibodies  >12 publications with EPHX2 and Atherosclerosis
 Kidney Diseases Antibodies  >10 publications with EPHX2 and Kidney Diseases
 Myocardial Reperfusion Injury Antibodies  >8 publications with EPHX2 and Myocardial Reperfusion Injury
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >56 publications with EPHX2 and Blood
 Heart Antibodies  >38 publications with EPHX2 and Heart
 Kidney Antibodies  >30 publications with EPHX2 and Kidney
 Brain Antibodies  >30 publications with EPHX2 and Brain
 Muscle Antibodies  >23 publications with EPHX2 and Muscle
 Liver Antibodies  >19 publications with EPHX2 and Liver
 Lung Antibodies  >10 publications with EPHX2 and Lung
 Pancreas Antibodies  >5 publications with EPHX2 and Pancreas
 Adipose Tissue Antibodies  >4 publications with EPHX2 and Adipose Tissue
 Adrenal Gland Antibodies  >3 publications with EPHX2 and Adrenal Gland
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