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anti-FCGR2A antibody :: Mouse anti-Human FCGR2A Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS533875
Unit / Price
0.1 mL  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FCGR2A, Monoclonal Antibody

★Popular Item★
 Also Known As   

FCGR2A antibody

 Product Synonym Names    Monoclonal FCGR2A; Anti-FCGR2A; Fc fragment of IgG low affinity IIa receptor CD32; CD32; IGFR2; CDw32; CD32A; Fc-gamma RII-a; IgG Fc receptor IIa; FCG2; FCGR2A1; CD32 antigen; FCGR2A; FCGRA 2; FCGRA-2
 Product Gene Name   

anti-FCGR2A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    146790
 3D Structure    ModBase 3D Structure for P12318
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    15G5
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    FCGR2A antibody was purified by affinity chromatography.
 Form/Format    Purified liquid from ascites in PBS, pH 7.3, with 1% BSA, 50% glycerol, and 0.02% sodium azide.
 Concentration    0.77mg/ml (lot specific)
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 Biological Significance    FCGR2A is a member of a family of immunoglobulin Fc receptor genes found on the surface of many immuneresponse cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such asmacrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes.
 Immunogen    Full length human recombinant protein of human FCGR2A produced in HEK293T cell
 Additional Remarks    Suitable for use in WB (1/200- 1/1000), IHC (1/50), IF (1/100), IP (2ug/500ul)
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 Preparation and Storage    Ships at 4 degee C only. Upon receipt store at -20 degree C. Dilute in PBS, pH 7.3, if necessary. Avoid repeat freeze/thaw cycles.
 Other Notes    Small volumes of anti-FCGR2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FCGR2A antibody

   Mouse monoclonal FCGR2A antibody
 Product Categories/Family for anti-FCGR2A antibody    Immunology
 Applications Tested/Suitable for anti-FCGR2A antibody   

Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-FCGR2A antibody    IF: 1:100
IHC: 1:50
WB: 1:1000
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 Western Blot (WB) of anti-FCGR2A antibody    Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant FCGR2A protein (Right) or empty vector (Left) detected with FCGR2A antibody
anti-FCGR2A antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-FCGR2A antibody    Immunohistochemical analysis of FCGR2A protein in paraffin embedded Human endometrium tissue using FCGR2A antibody
anti-FCGR2A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for FCGR2A. It may not necessarily be applicable to this product.
 NCBI GI #    55960610
 NCBI Accession #    CAI16119.1 [Other Products]
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 UniProt Primary Accession #    P12318 [Other Products]
 UniProt Secondary Accession #    Q8WUN1; Q8WW64 [Other Products]
 Molecular Weight    34,930 Da
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 UniProt Protein Name    Low affinity immunoglobulin gamma Fc region receptor II-a
 UniProt Synonym Protein Names   
CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD_antigen: CD32
 Protein Family    Low affinity immunoglobulin gamma Fc region receptor
 UniProt Gene Name    FCGR2A [Similar Products]
 UniProt Synonym Gene Names    CD32; FCG2; FCGR2A1; IGFR2; IgG Fc receptor II-a; Fc-gamma-RIIa; FcRII-a [Similar Products]
 UniProt Entry Name    FCG2A_HUMAN
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 UniProt Comments for FCGR2A    FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells.

Protein type: Cell surface; Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: integral to membrane; plasma membrane

Molecular Function: IgG binding

Biological Process: innate immune response

Disease: Systemic Lupus Erythematosus; Malaria, Susceptibility To
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FCGR2A antibodyDiseases associated with anti-FCGR2A antibody
 Reference Product  PubMed Publications
 ITGAM antibody  >3 publications with FCGR2A and ITGAM
 SYK antibody  >3 publications with FCGR2A and SYK
 ITGB2 antibody  >2 publications with FCGR2A and ITGB2
 APCS antibody  >2 publications with FCGR2A and APCS
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >51 publications with FCGR2A and Autoimmune Diseases
 Lupus Erythematosus, Systemic Antibodies  >27 publications with FCGR2A and Lupus Erythematosus, Systemic
 Arthritis, Rheumatoid Antibodies  >22 publications with FCGR2A and Arthritis, Rheumatoid
 Inflammation Antibodies  >20 publications with FCGR2A and Inflammation
 Necrosis Antibodies  >16 publications with FCGR2A and Necrosis
 Lung Diseases Antibodies  >14 publications with FCGR2A and Lung Diseases
 Intestinal Diseases Antibodies  >13 publications with FCGR2A and Intestinal Diseases
 Thrombocytopenia Antibodies  >10 publications with FCGR2A and Thrombocytopenia
 Mucocutaneous Lymph Node Syndrome Antibodies  >9 publications with FCGR2A and Mucocutaneous Lymph Node Syndrome
 Pneumonia Antibodies  >8 publications with FCGR2A and Pneumonia
Organs/Tissues associated with anti-FCGR2A antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >77 publications with FCGR2A and Blood
 Vascular Antibodies  >10 publications with FCGR2A and Vascular
 Heart Antibodies  >7 publications with FCGR2A and Heart
 Lung Antibodies  >6 publications with FCGR2A and Lung
 Bone Antibodies  >6 publications with FCGR2A and Bone
 Bone Marrow Antibodies  >4 publications with FCGR2A and Bone Marrow
 Skin Antibodies  >4 publications with FCGR2A and Skin
 Kidney Antibodies  >3 publications with FCGR2A and Kidney
 Connective Tissue Antibodies  >2 publications with FCGR2A and Connective Tissue
 Liver Antibodies  >2 publications with FCGR2A and Liver
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