NP_060761.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
FGGY carbohydrate kinase domain-containing protein isoform b
NCBI Official Synonym Full Names
FGGY carbohydrate kinase domain containing
NCBI Protein Information
FGGY carbohydrate kinase domain-containing protein
UniProt Protein Name
FGGY carbohydrate kinase domain-containing protein
UniProt Entry Name
FGGY_HUMAN
NCBI Summary for FGGY
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
UniProt Comments for FGGY
FGGY: Defects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS). Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. Belongs to the FGGY kinase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, other; EC 2.7.1.-
Chromosomal Location of Human Ortholog: 1p32.1
Molecular Function: kinase activity; phosphotransferase activity, alcohol group as acceptor
Biological Process: carbohydrate metabolic process; phosphorylation
Research Articles on FGGY
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Products associated with anti-FGGY antibody
Diseases associated with anti-FGGY antibody
Organs/Tissues associated with anti-FGGY antibody
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