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anti-FLRT1 antibody :: Mouse anti-Human FLRT1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2543607 anti-FLRT1 antibody
Unit / Price
0.06 mL  /  $215 +1 FREE 8GB USB
0.12 mL  /  $330 +1 FREE 8GB USB
0.2 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FLRT1, Monoclonal Antibody

 Also Known As   

Mouse anti Human FLRT1 Monoclonal Antibody

 Product Gene Name   

anti-FLRT1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF169675 mRNA
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 Clonality    Monoclonal
 Isotype    IgG1
 Host    Mouse
 Species Reactivity    Human
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 Immunogen    Recombinant Human FLRT1 protein
 Buffer    0.2 mum filtered solution in PBS with 5% trehalose
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 Preparation and Storage    This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-FLRT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FLRT1 antibody   

ELISA (EIA)

 Application Notes for anti-FLRT1 antibody    ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human FLRT1. The detection limit for Human FLRT1 is approximately 0.039 ng/well.
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NCBI/Uniprot data below describe general gene information for FLRT1. It may not necessarily be applicable to this product.
 NCBI GI #    37181736
 NCBI GeneID    23769
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 UniProt Secondary Accession #    Q8WVA2 [Other Products]
 UniProt Related Accession #    Q9NZU1 [Other Products]
 Molecular Weight    71,358 Da
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 NCBI Official Full Name    FLRT1
 NCBI Official Synonym Full Names    fibronectin leucine rich transmembrane protein 1
 NCBI Official Symbol    FLRT1 [Similar Products]
 NCBI Official Synonym Symbols   
SPG68
[Similar Products]
 NCBI Protein Information    leucine-rich repeat transmembrane protein FLRT1
 UniProt Protein Name    Leucine-rich repeat transmembrane protein FLRT1
 UniProt Synonym Protein Names   
Fibronectin-like domain-containing leucine-rich transmembrane protein 1
 Protein Family    Leucine-rich repeat transmembrane protein
 UniProt Gene Name    FLRT1 [Similar Products]
 UniProt Entry Name    FLRT1_HUMAN
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 NCBI Summary for FLRT1    This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FLRT1    FLRT1: May have a function in cell adhesion and/or receptor signaling.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: cytoplasm; cytoplasmic vesicle; focal adhesion; integral to plasma membrane; intercellular junction; perinuclear region of cytoplasm; plasma membrane

Molecular Function: protein kinase inhibitor activity

Biological Process: cytokine and chemokine mediated signaling pathway; dendrite development; fibroblast growth factor receptor signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity
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 Research Articles on FLRT1    1. the phosphorylation state of FLRT1, which is itself FGFR1 dependent, may play a critical role in the potentiation of FGFR1 signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FLRT1 antibodyPathways associated with anti-FLRT1 antibody
 Reference Product  PubMed Publications
 FLRT2 antibody  >5 publications with FLRT1 and FLRT2
 FGFR1 antibody  >2 publications with FLRT1 and FGFR1
 Products by Pathway  Pathway Diagram
 Downstream Signaling Of Activated FGFR1 Pathway antibodies  Downstream Signaling Of Activated FGFR1 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By FGFR Pathway antibodies  Signaling By FGFR Pathway Diagram
 Signaling By FGFR1 Pathway antibodies  Signaling By FGFR1 Pathway Diagram
Organs/Tissues associated with anti-FLRT1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with FLRT1 and Brain
 Embryonic Tissue Antibodies  >1 publications with FLRT1 and Embryonic Tissue
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