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| Product Name
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FLRT1, Monoclonal Antibody
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| Also Known As
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Mouse anti Human FLRT1 Monoclonal Antibody
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| OMIM
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AF169675 mRNA
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| Clonality
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Monoclonal
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| Isotype
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IgG1
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| Host
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Mouse
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| Species Reactivity
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Human
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| Immunogen
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Recombinant Human FLRT1 protein
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| Buffer
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0.2 mum filtered solution in PBS with 5% trehalose
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| Preparation and Storage
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This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
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| Other Notes
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Small volumes of anti-FLRT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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TOP
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| Applications Tested/Suitable for anti-FLRT1 antibody
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ELISA (EIA)
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| Application Notes for anti-FLRT1 antibody
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ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human FLRT1. The detection limit for Human FLRT1 is approximately 0.039 ng/well.
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TOP
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| NCBI/Uniprot data below describe general gene information for FLRT1. It may not necessarily be applicable to this product. |
| NCBI GI #
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37181736
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| NCBI GeneID
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23769
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| UniProt Secondary Accession #
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Q8WVA2
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[Other Products]
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| UniProt Related Accession #
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Q9NZU1
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[Other Products]
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| Molecular Weight
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71,358 Da
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TOP
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| NCBI Official Full Name
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FLRT1
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| NCBI Official Synonym Full Names
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fibronectin leucine rich transmembrane protein 1
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| NCBI Official Symbol
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FLRT1
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[Similar Products]
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| NCBI Official Synonym Symbols
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SPG68
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[Similar Products]
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| NCBI Protein Information
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leucine-rich repeat transmembrane protein FLRT1
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| UniProt Protein Name
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Leucine-rich repeat transmembrane protein FLRT1
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| UniProt Synonym Protein Names
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Fibronectin-like domain-containing leucine-rich transmembrane protein 1
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| Protein Family
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Leucine-rich repeat transmembrane protein
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| UniProt Gene Name
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FLRT1
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[Similar Products]
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| UniProt Entry Name
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FLRT1_HUMAN
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| NCBI Summary for FLRT1
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This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]
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| UniProt Comments for FLRT1
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FLRT1: May have a function in cell adhesion and/or receptor signaling.
Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11q13.1
Cellular Component: cytoplasm; cytoplasmic vesicle; focal adhesion; integral to plasma membrane; intercellular junction; perinuclear region of cytoplasm; plasma membrane
Molecular Function: protein kinase inhibitor activity
Biological Process: cytokine and chemokine mediated signaling pathway; dendrite development; fibroblast growth factor receptor signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity
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TOP
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| Research Articles on FLRT1
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1. the phosphorylation state of FLRT1, which is itself FGFR1 dependent, may play a critical role in the potentiation of FGFR1 signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR
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TOP
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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TOP
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| Products associated with anti-FLRT1 antibody | Pathways associated with anti-FLRT1 antibody |
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| Organs/Tissues associated with anti-FLRT1 antibody |
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TOP
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Antibody 
