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anti-FSH antibody :: Mouse FSH Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS531141 anti-FSH antibody
Unit / Price
1 mg  /  $480 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FSH, Monoclonal Antibody

 Also Known As   

FSH antibody

 Product Synonym Names    Monoclonal FSH; Anti-FSH; Follicle Stimulating Hormone
 Product Gene Name   

anti-FSH antibody

[Similar Products]
 Matching Pairs    Capture Antibody: FSH Clone #M607109 (MBS531141)
Detection Antibody: FSH beta Clone #M94167 (MBS530713)
Comments: Very good pair for ELISA
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    136530
 3D Structure    ModBase 3D Structure for P01225
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 Clonality    Monoclonal
 Isotype    IgG2a kappa
 Clone Number    M607109
 Host    Mouse
 Species Reactivity    To be determined by end-user
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 Purity/Purification    > 90% pure
 Form/Format    10mM Na3PO4, pH 7.5, with 150mM NaCl and 0.1% NaN3.
 Concentration    Typically 3-5 mg/ml (lot specific)
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 Biological Significance    Follicle-stimulating hormone (FSH) is a hormone found in humans and other animals. It is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and Luteinizing hormone (LH) act synergistically in reproduction.
 Immunogen    FSH antibody was raised in mouse using high purity intact FSH from human pituitary gland as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-FSH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FSH antibody

   Mouse monoclonal FSH antibody
 Product Categories/Family for anti-FSH antibody    Hormones & Steroids
 Applications Tested/Suitable for anti-FSH antibody   

ELISA (EIA)

 Application Notes for anti-FSH antibody    MBS531141 can be used as the capture antibody in a matched pair immunoassay in conjunction with MBS530713 as the detection antibody
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NCBI/Uniprot data below describe general gene information for FSH. It may not necessarily be applicable to this product.
 NCBI GI #    182762
 NCBI GeneID    2488
 NCBI Accession #    AAA52476.1 [Other Products]
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 UniProt Primary Accession #    P01225 [Other Products]
 UniProt Secondary Accession #    Q14D61; A2TF08; A5JVV3 [Other Products]
 UniProt Related Accession #    P01225 [Other Products]
 Molecular Weight    14,700 Da
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 NCBI Official Full Name    follicle-stimulating hormone
 NCBI Official Synonym Full Names    follicle stimulating hormone, beta polypeptide
 NCBI Official Symbol    FSHB [Similar Products]
 NCBI Official Synonym Symbols   
HH24
[Similar Products]
 NCBI Protein Information    follitropin subunit beta
 UniProt Protein Name    Follitropin subunit beta
 UniProt Synonym Protein Names   
Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain
 UniProt Gene Name    FSHB [Similar Products]
 UniProt Synonym Gene Names    FSH-B; FSH-beta [Similar Products]
 UniProt Entry Name    FSHB_HUMAN
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 NCBI Summary for FSH    The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FSH    FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm; extracellular region

Molecular Function: follicle-stimulating hormone activity; protein binding; hormone activity

Biological Process: progesterone biosynthetic process; follicle-stimulating hormone signaling pathway; peptide hormone processing; female gamete generation; Sertoli cell proliferation; female pregnancy; signal transduction; cellular protein metabolic process; regulation of osteoclast differentiation; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; positive regulation of bone resorption; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration

Disease: Follicle-stimulating Hormone Deficiency, Isolated
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 Research Articles on FSH    1. 3 known FSH-action modulating SNPs (FSHB -211G/T; FSHR -29G/A, c.2039 A/G)explained together 2.3%, 1.4%, 1.0 and 1.1% of the measured variance in serum FSH, Inhibin B, testosterone and total testes volume, respectively.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FSH antibodyPathways associated with anti-FSH antibody
 Reference Product  PubMed Publications
 FSHR antibody  >30 publications with FSH and FSHR
 CGA antibody  >29 publications with FSH and CGA
 INHA antibody  >4 publications with FSH and INHA
 INHBB antibody  >3 publications with FSH and INHBB
 INHBA antibody  >1 publications with FSH and INHBA
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 FSH Signaling Pathway antibodies  FSH Signaling Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 Hormone Ligand-binding Receptors Pathway antibodies  Hormone Ligand-binding Receptors Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
Diseases associated with anti-FSH antibodyOrgans/Tissues associated with anti-FSH antibody
 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >19 publications with FSH and Infertility, Male
 Infertility, Female Antibodies  >12 publications with FSH and Infertility, Female
 Kidney Diseases Antibodies  >10 publications with FSH and Kidney Diseases
 Hypogonadism Antibodies  >6 publications with FSH and Hypogonadism
 Nervous System Diseases Antibodies  >5 publications with FSH and Nervous System Diseases
 Breast Neoplasms Antibodies  >2 publications with FSH and Breast Neoplasms
 Oligospermia Antibodies  >2 publications with FSH and Oligospermia
 Weight Gain Antibodies  >1 publications with FSH and Weight Gain
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with FSH and Prenatal Exposure Delayed Effects
 Follicle-stimulating hormone deficiency, isolated Antibodies  >1 publications with FSH and Follicle-stimulating hormone deficiency, isolated
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >86 publications with FSH and Brain
 Pituitary Gland Antibodies  >74 publications with FSH and Pituitary Gland
 Testis Antibodies  >27 publications with FSH and Testis
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