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anti-Fabp3 antibody :: Mouse anti-Human Fatty Acid Binding Protein, Heart Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS602230 anti-Fabp3 antibody
Unit / Price
0.1 mg  /  $745 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fatty Acid Binding Protein, Heart (Fabp3), Monoclonal Antibody

 Also Known As   

Fatty Acid Binding Protein, Heart (FABP)

 Product Synonym Names    Anti -Fatty Acid Binding Protein, Heart (FABP)
 Product Gene Name   

anti-Fabp3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_005104.2 (149340525..149347268). Location: 5q36
 3D Structure    ModBase 3D Structure for P07483
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    3H429
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognizes human heart FABP. Isoform crossreactivity
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.4 and 0.1% sodium azide, 40% glycerol.
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 Immunogen    Purified human heart FABP (> 98%).
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-Fabp3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Fabp3 antibody

   Fatty acids are important for general cellular metabolism. A number of proteins have been implicated in the transport and storage of fatty acid. FABPs (fatty acid binding proteins) are a group of cytoplasmic, small mol wt (14-15kD) and proteins that has widespread tissue distribution. FABPs are quite abundant (3-5% of total cellular protein). At least 7 FABPs, FABP1-7, have been cloned and characterized from various tissues. FABPs can bind long-chain fatty acid, fatty-acid acyl-CoA and acyl-L-carnitine. Several different isoform of FABP have been identified and generally referred to by tissue type (liver, heart, intestine, adipocyte, kidney, brain etc; protein designated as H-FABP indicates that it is heart type). However, expression of these isoform is not exclusive and more than one isoform can be found in aH given cell or tissue. Three main types of FABPs that were initially discovered in the heart (FABP-), liver (FABP-L), and intestine (FABP-I) are not exclusive these tissues and show considerable differences at the amino acid level (~30% identity). Other FABPs recently detected in adipocyte, kidney, and brain show a high degree of sequence homology among each other and with other FABPs. FABPs are also known as mammary derived growth inhibitor (MDGI), adipocyte lipid binding protein (ALBP), Myelin protein P2 homolog, P2 adipocyte protein, 422 protein (P15). Human FABP-H or adipocyte is 132-aa protein (chromosome 2p11) Rat and mouse adipocyte-FABPs are 133 aa single polypeptide chains.
 Product Categories/Family for anti-Fabp3 antibody    Antibodies; Abs to Fatty Acid Binding Protein
 Applications Tested/Suitable for anti-Fabp3 antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-Fabp3 antibody    Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1:1000-1:5000. Use +ve as control (refer to Catalog F0019-77M). Load ~10ul/lane.
ELISA: 1:10,000-1:50,000.
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NCBI/Uniprot data below describe general gene information for Fabp3. It may not necessarily be applicable to this product.
 NCBI GI #    13162363
 NCBI GeneID    79131
 NCBI Accession #    NP_077076.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_024162.1 [Other Products]
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 UniProt Primary Accession #    P07483 [Other Products]
 UniProt Secondary Accession #    Q9QY04 [Other Products]
 UniProt Related Accession #    P07483 [Other Products]
 Molecular Weight    14,775 Da [Similar Products]
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 NCBI Official Full Name    fatty acid-binding protein, heart
 NCBI Official Synonym Full Names    fatty acid binding protein 3, muscle and heart
 NCBI Official Symbol    Fabp3 [Similar Products]
 NCBI Official Synonym Symbols   
Fabp3
[Similar Products]
 NCBI Protein Information    fatty acid-binding protein, heart; H-FABP; fatty acid-binding protein 3; heart fatty acid binding protein; Fatty acid binding protein 3 heart; fatty acid binding protein 3 heart; heart-type fatty acid-binding protein
 UniProt Protein Name    Fatty acid-binding protein, heart
 UniProt Synonym Protein Names   
Fatty acid-binding protein 3; Heart-type fatty acid-binding protein
 Protein Family    Fatty acid-binding protein
 UniProt Gene Name    Fabp3 [Similar Products]
 UniProt Entry Name    FABPH_RAT
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 NCBI Summary for Fabp3    binds fatty acids; may play a role in fatty acid metabolism possibly including mitochondrial beta-oxidation of fatty acids [RGD]
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 UniProt Comments for Fabp3    FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Cellular Component: extracellular space; mitochondrion; sarcoplasmic reticulum; cytoplasm; cytosol; sarcoplasm

Molecular Function: icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity; fatty acid binding

Biological Process: response to drug; long-chain fatty acid transport; cholesterol homeostasis; fatty acid beta-oxidation; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis
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 Research Articles on Fabp3    1. H-FABP might have potential to be an early and quantitative parameter of clinical severity and prognosis in CO poisoning.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Fabp3 antibodyDiseases associated with anti-Fabp3 antibody
 Products by Pathway  Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >83 publications with Fabp3 and Cardiovascular Diseases
 Heart Diseases Antibodies  >70 publications with Fabp3 and Heart Diseases
 Myocardial Ischemia Antibodies  >52 publications with Fabp3 and Myocardial Ischemia
 Myocardial Infarction Antibodies  >42 publications with Fabp3 and Myocardial Infarction
 Neoplasms Antibodies  >27 publications with Fabp3 and Neoplasms
 Fatty Liver Antibodies  >21 publications with Fabp3 and Fatty Liver
 Necrosis Antibodies  >17 publications with Fabp3 and Necrosis
 Breast Neoplasms Antibodies  >15 publications with Fabp3 and Breast Neoplasms
 Skin Diseases Antibodies  >14 publications with Fabp3 and Skin Diseases
 Carcinoma Antibodies  >12 publications with Fabp3 and Carcinoma
Organs/Tissues associated with anti-Fabp3 antibody
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >136 publications with Fabp3 and Heart
 Muscle Antibodies  >80 publications with Fabp3 and Muscle
 Adipose Tissue Antibodies  >19 publications with Fabp3 and Adipose Tissue
 Nerve Antibodies  >17 publications with Fabp3 and Nerve
 Kidney Antibodies  >15 publications with Fabp3 and Kidney
 Ovary Antibodies  >3 publications with Fabp3 and Ovary
 Eye Antibodies  >2 publications with Fabp3 and Eye
 Placenta Antibodies  >2 publications with Fabp3 and Placenta
 Inner Ear Antibodies  >1 publications with Fabp3 and Inner Ear
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