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anti-FABP1 antibody :: Mouse anti-Human Fatty Acid Binding Protein, Liver Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS601001 anti-FABP1 antibody
Unit / Price
0.1 mg  /  $760 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fatty Acid Binding Protein, Liver (FABP1), Monoclonal Antibody

 Also Known As   

Fatty Acid Binding Protein, Liver (FABP)

 Product Synonym Names    Anti -Fatty Acid Binding Protein, Liver (FABP)
 Product Gene Name   

anti-FABP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (88422510..88427578, complement). Location: 2p11
 OMIM    134650
 3D Structure    ModBase 3D Structure for P07148
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    6A553
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognizes native and recombinant human liver FABP. May show weak reactivity to heart FABP.
 Purity/Purification    Affinity Purified
Purified immunoglobulin.
 Form/Format    Supplied as a liquid in PBS, 0.1% BSA and 0.02% sodium azide.
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 Immunogen    Human liver FABP at ~14kD.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-FABP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FABP1 antibody

   Liver FABP is localized in the liver and intestinal epithelium. The antibody is useful to detect ischemic areas of human liver.
 Product Categories/Family for anti-FABP1 antibody    Antibodies; Abs to Fatty Acid Binding Protein
 Applications Tested/Suitable for anti-FABP1 antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-FABP1 antibody    Can be used for ELISA, Immunohistochemistry, Western Blot and for purification of human liver FABP.
Dilution: Immunohistochemistry (Frozen sections): 1:50
Western Blot: 1:50
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NCBI/Uniprot data below describe general gene information for FABP1. It may not necessarily be applicable to this product.
 NCBI GI #    4557577
 NCBI GeneID    2168
 NCBI Accession #    NP_001434.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001443.2 [Other Products]
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 UniProt Primary Accession #    P07148 [Other Products]
 UniProt Related Accession #    P07148; Q05CP7; Q6FGL7 [Other Products]
 Molecular Weight    14,208 Da [Similar Products]
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 NCBI Official Full Name    fatty acid-binding protein, liver
 NCBI Official Synonym Full Names    fatty acid binding protein 1, liver
 NCBI Official Symbol    FABP1 [Similar Products]
 NCBI Official Synonym Symbols   
FABPL; L-FABP
[Similar Products]
 NCBI Protein Information    fatty acid-binding protein, liver; OTTHUMP00000160828; OTTHUMP00000160829; fatty acid-binding protein 1; liver-type fatty acid-binding protein
 UniProt Protein Name    Fatty acid-binding protein, liver
 UniProt Synonym Protein Names   
Fatty acid-binding protein 1; Liver-type fatty acid-binding protein
 Protein Family    Fatty acid-binding protein
 UniProt Gene Name    FABP1 [Similar Products]
 UniProt Synonym Gene Names    FABPL [Similar Products]
 UniProt Entry Name    FABPL_HUMAN
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 NCBI Summary for FABP1    This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq]
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 UniProt Comments for FABP1    FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol

Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; long-chain fatty acid transporter activity; drug binding; chromatin binding; fatty acid binding

Biological Process: long-chain fatty acid transport; positive regulation of cell proliferation; positive regulation of hydrolase activity; negative regulation of caspase activity; cellular lipid metabolic process; intestinal absorption; negative regulation of apoptosis; positive regulation of fatty acid beta-oxidation
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 Research Articles on FABP1    1. Renal hL-FABP reduced the oxidative stress in aristolochic acid-induced nephrotoxicity and attenuated tubulointerstitial damage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FABP1 antibodyPathways associated with anti-FABP1 antibody
 Reference Product  PubMed Publications
 PPARG antibody  >6 publications with FABP1 and PPARG
 PPARA antibody  >1 publications with FABP1 and PPARA
 Products by Pathway  Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram
Diseases associated with anti-FABP1 antibodyOrgans/Tissues associated with anti-FABP1 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >259 publications with FABP1 and Fatty Liver
 Liver Diseases Antibodies  >41 publications with FABP1 and Liver Diseases
 Female Urogenital Diseases Antibodies  >40 publications with FABP1 and Female Urogenital Diseases
 Kidney Diseases Antibodies  >39 publications with FABP1 and Kidney Diseases
 Neoplasms Antibodies  >38 publications with FABP1 and Neoplasms
 Liver Neoplasms Antibodies  >24 publications with FABP1 and Liver Neoplasms
 Carcinoma Antibodies  >20 publications with FABP1 and Carcinoma
 Diabetes Mellitus Antibodies  >17 publications with FABP1 and Diabetes Mellitus
 Renal Insufficiency Antibodies  >16 publications with FABP1 and Renal Insufficiency
 Adenocarcinoma Antibodies  >13 publications with FABP1 and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >264 publications with FABP1 and Liver
 Intestine Antibodies  >90 publications with FABP1 and Intestine
 Kidney Antibodies  >48 publications with FABP1 and Kidney
 Muscle Antibodies  >17 publications with FABP1 and Muscle
 Stomach Antibodies  >10 publications with FABP1 and Stomach
 Embryonic Tissue Antibodies  >10 publications with FABP1 and Embryonic Tissue
 Placenta Antibodies  >5 publications with FABP1 and Placenta
 Lung Antibodies  >4 publications with FABP1 and Lung
 Prostate Antibodies  >3 publications with FABP1 and Prostate
 Skin Antibodies  >2 publications with FABP1 and Skin
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