Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow FBLN1 rightarrow Monoclonal FBLN1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Tissue, Section Disease, Alzheimer's Disease, Brain, Hippoca... Tissue Section
 • VEGF Antibody
 • complement component 1, r subcomponent (C1R) ELISA Kit
 • TFEB Antibody
 • Lipopolysaccharide Binding Protein (LBP) ELISA Kit
 • INT6 Antibody
 • CLDN5 - Claudin 5 Antibody
 • PTPRC Antibody
 • Goat Anti-Mouse IgM+IgG+IgA(H+L) Secondary Antibody
 • Chymotrypsin (CTRC) Native Protein
 • crystallin, beta A1 (CRYBA1) ELISA Kit
 • 72 kDa type IV collagenase (MMP2) Recombinant Protein
 • PPP1R15B Antibody
 • Lysyl oxidase homolog 1 (Loxl1) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-FBLN1 antibody :: Mouse Fibulin 1 (FBLN1) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2085940 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $100 +1 FREE 8GB USB
0.02 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $140 +1 FREE 8GB USB
0.1 mg  /  $175 +1 FREE 8GB USB
0.2 mg  /  $225 +1 FREE 8GB USB
1 mg  /  $505 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibulin 1 (FBLN1), Monoclonal Antibody

★Popular Item★
 Also Known As   

Monoclonal Antibody to Fibulin 1 (FBLN1)

 Product Gene Name   

anti-FBLN1 antibody

[Similar Products]
 Matching Pairs    Antibody: Fibulin 1 (FBLN1) (MBS2085940)
Antigen: Fibulin 1 (FBLN1) (MBS2010143)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
APC-CY7 Conjugated Antibody: Fibulin 1 (FBLN1) (MBS2065944)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
PE Conjugated Antibody: Fibulin 1 (FBLN1) (MBS2065946)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
APC-CY7 Conjugated Antibody: Fibulin 1 (FBLN1) (MBS2065948)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
Cy3 Conjugated Antibody: Fibulin 1 (FBLN1) (MBS2065950)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
FITC Conjugated Antibody: Fibulin 1 (FBLN1) (MBS2065952)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
HRP Conjugated Antibody: Fibulin 1 (FBLN1) (MBS2065954)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
Biotin Conjugated Secondary Antibody: IgG (MBS2086030)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
FITC Conjugated Secondary Antibody: IgG (MBS2086031)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
Biotin Conjugated Secondary Antibody: IgG (MBS2086033)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
FITC Conjugated Secondary Antibody: IgG (MBS2086034)
 Matching Pairs    Unconjugated Antibody: Fibulin 1 (FBLN1) (MBS2085940)
HRP Conjugated Secondary Antibody: IgG (MBS2086035)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 MBS2085940 Technical Datasheet    Technical Datasheet PDF
 OMIM    X53741 mRNA
 3D Structure    ModBase 3D Structure for P23142
Section Bar
 Clonality    Monoclonal
 Isotype    IgG2a Kappa
 Host    Mouse
Section Bar
 Purity/Purification    Protein A + Protein G affinity chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Concentration    1 mg/ml (lot specific)
Section Bar
 Organism Species    Homo sapiens (Human)
 Source    Monoclonal antibody preparation
 Antibody isotype    IgG2b Kappa
 Clone number    D1
 Traits    Liquid
 Immunogen    Recombinant FBLN1 (Leu176~Val398 (Accession # P23142)) expressed in E.coli
Section Bar
 Preparation and Storage    Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-FBLN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-FBLN1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

 Application Notes for anti-FBLN1 antibody    Western blotting: 0.5-2 ug/mL;1:500-2000
Immunohistochemistry: 5-20 ug/mL;1:50-200
Immunocytochemistry: 5-20 ug/mL;1:50-200

Optimal working dilutions must be determined by end user.
Section Bar
 Western Blot (WB) of anti-FBLN1 antibody    (Figure. Western Blot; Samples.

Lane1: Human Serum
Lane2: Rat Placenta Tissue;)
anti-FBLN1 antibody Western Blot (WB) (WB) image
Section Bar
 Western Blot (WB) of anti-FBLN1 antibody    (Figure. Western Blot; Sample: Recombinant FLBN1 Human)
anti-FBLN1 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-FBLN1 antibody    DAB staining on IHC-P; Samples
Human Prostate Tissue
Primary Ab: 20 ug/ml Mouse Anti-Human FBLN1 Antibody
Second Ab: 2 ug/mL HRP-Linked Caprine Anti-Mouse
IgG Polyclonal Antibody (Catalog: MBS2086035)
anti-FBLN1 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for FBLN1. It may not necessarily be applicable to this product.
 NCBI GI #    34734062
 NCBI GeneID    2192
 NCBI Accession #    NP_001987.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001996.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P23142 [Other Products]
 UniProt Secondary Accession #    P23143; P23144; P37888; Q5TIC4; Q8TBH8; Q9HBQ5; Q9UC21; Q9UGR4; Q9UH41; B0QY42; B1AHL4 [Other Products]
 UniProt Related Accession #    P23142 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    fibulin-1 isoform C
 NCBI Official Synonym Full Names    fibulin 1
 NCBI Official Symbol    FBLN1 [Similar Products]
 NCBI Official Synonym Symbols   
FBLN; FIBL1
[Similar Products]
 NCBI Protein Information    fibulin-1
 UniProt Protein Name    Fibulin-1
 UniProt Gene Name    FBLN1 [Similar Products]
 UniProt Synonym Gene Names    FIBL-1 [Similar Products]
Section Bar
 NCBI Summary for FBLN1    Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for FBLN1    FBLN1: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP. A chromosomal aberration involving FBLN1 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with C12orf2. Fibroblasts derived from a patient with synpolydactyly displayed alterations in the level of isoform D splice variant incorporated into the ECM and secreted into the conditioned culture medium. By contrast, the expression of isoform C was not perturbed in the patients fibroblasts. Furthermore, no aberrant polypeptides were detected in extracts of cultured patients fibroblasts. The translocation t(12;22) may result in haploinsufficiency of the isoform D splice variant, which could lead to the observed limb malformation. Elevated expression and altered processing of FBLN1 protein is associated with human breast cancer. Belongs to the fibulin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q13.31

Cellular Component: basement membrane; extracellular matrix; extracellular region; extracellular space; fibrinogen complex; proteinaceous extracellular matrix

Molecular Function: calcium ion binding; extracellular matrix structural constituent; fibronectin binding; identical protein binding; protease activator activity; protein C-terminus binding; protein complex binding

Biological Process: embryo implantation; extracellular matrix organization; integrin-mediated signaling pathway; negative regulation of cell adhesion; negative regulation of protein phosphorylation; viral process

Disease: Synpolydactyly 2
Table BarTOPTable Bar
 Research Articles on FBLN1    1. Galectin-3 and fibulin-1 levels are elevated in heart failure patients with impaired glucose metabolism. Reduced LV contractile reserve among HF patients with DM does not to have an independent impact on plasma Gal-3 and fibulin-1 levels.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-FBLN1 antibodyPathways associated with anti-FBLN1 antibody
 Reference Product  PubMed Publications
 VCAN antibody  >3 publications with FBLN1 and VCAN
 FBLN5 antibody  >2 publications with FBLN1 and FBLN5
 EFEMP1 antibody  >1 publications with FBLN1 and EFEMP1
 NID1 antibody  >1 publications with FBLN1 and NID1
 HSPG2 antibody  >1 publications with FBLN1 and HSPG2
 MFAP5 antibody  >1 publications with FBLN1 and MFAP5
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram
Diseases associated with anti-FBLN1 antibodyOrgans/Tissues associated with anti-FBLN1 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >9 publications with FBLN1 and Carcinoma
 Disease Models, Animal Antibodies  >6 publications with FBLN1 and Disease Models, Animal
 Adenocarcinoma Antibodies  >5 publications with FBLN1 and Adenocarcinoma
 Prostatic Neoplasms Antibodies  >4 publications with FBLN1 and Prostatic Neoplasms
 Fibrosis Antibodies  >3 publications with FBLN1 and Fibrosis
 Kidney Diseases Antibodies  >3 publications with FBLN1 and Kidney Diseases
 Neoplasms, Experimental Antibodies  >3 publications with FBLN1 and Neoplasms, Experimental
 Brain Diseases Antibodies  >2 publications with FBLN1 and Brain Diseases
 Inflammation Antibodies  >2 publications with FBLN1 and Inflammation
 Synpolydactyly 2 Antibodies  >2 publications with FBLN1 and Synpolydactyly 2
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >12 publications with FBLN1 and Blood
 Embryonic Tissue Antibodies  >6 publications with FBLN1 and Embryonic Tissue
 Eye Antibodies  >6 publications with FBLN1 and Eye
 Prostate Antibodies  >4 publications with FBLN1 and Prostate
 Nerve Antibodies  >4 publications with FBLN1 and Nerve
 Bone Antibodies  >4 publications with FBLN1 and Bone
 Muscle Antibodies  >4 publications with FBLN1 and Muscle
 Heart Antibodies  >4 publications with FBLN1 and Heart
 Lung Antibodies  >3 publications with FBLN1 and Lung
 Kidney Antibodies  >3 publications with FBLN1 and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions