NP_000803.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit beta-1
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, beta 1
NCBI Protein Information
gamma-aminobutyric acid receptor subunit beta-1; GABA(A) receptor, beta 1; GABA(A) receptor subunit beta-1
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit beta-1
UniProt Synonym Protein Names
GABA(A) receptor subunit beta-1
UniProt Entry Name
GBRB1_HUMAN
NCBI Summary for GABRB1
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRB1
GABRB1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ion channel; Channel, chloride; Channel, ligand-gated; Transporter
Chromosomal Location of Human Ortholog: 4p12
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: chloride channel activity; GABA-A receptor activity; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity
Biological Process: synaptic transmission; transport; ion transport; signal transduction; transmembrane transport
Research Articles on GABRB1
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Products associated with anti-GABRB1 antibody
Pathways associated with anti-GABRB1 antibody
Diseases associated with anti-GABRB1 antibody
Organs/Tissues associated with anti-GABRB1 antibody
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