View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-GABPA antibody :: Mouse anti-Human, Mouse GABPA Monoclonal Antibody Catalog # MBS475824 Unit / Price 0.1 mL / $455 +1 FREE 8GB USB 5x0.1 mL / $1,565 +1 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name GABPA, Monoclonal Antibody Popular Item Full Product Name Anti-GABPA Mouse mAb Product Synonym Names NFT2; NRF2 Product Gene Name anti-GABPA antibody[Similar Products] Product Synonym Gene Name NFT2; NRF2[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM D13318 mRNA Clonality Monoclonal Isotype IgG1 Clone Number 8C1B10 Host Mouse Species Reactivity Human, Mouse Form/Format Ascitic fluid containing 0.03% sodium azide. Immunogen Purified recombinant fragment of human GABPA (aa120-190) expressed in E Coli. Other Notes Small volumes of anti-GABPA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-GABPA antibody Entrez Summary: GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype. Applications Tested/Suitable for anti-GABPA antibody Western Blot (WB), Immunocytochemistry (ICC) Western Blot (WB) of anti-GABPA antibody Western blot analysis using GABPA mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GABPA cDNA (2). Western Blot (WB) of anti-GABPA antibody Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF-7 (3), NIH/3T3 (4) and SMMC-7721 (5) cell lysate. Immunofluorescence (IF) of anti-GABPA antibody Confocal immunofluorescence analysis of Hela cells using GABPA mouse mAb (green). Red TOP NCBI/Uniprot data below describe general gene information for GABPA. It may not necessarily be applicable to this product. NCBI GI # 958707772 NCBI GeneID 2551 NCBI Accession # JAO71888.1 [Other Products] UniProt Secondary Accession # Q12939[Other Products] UniProt Related Accession # Q06546[Other Products] Molecular Weight 51 TOP NCBI Official Full Name GABPA NCBI Official Synonym Full Names GA binding protein transcription factor alpha subunit NCBI Official Symbol GABPA [Similar Products] NCBI Official Synonym Symbols NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07 [Similar Products] NCBI Protein Information GA-binding protein alpha chain UniProt Protein Name GA-binding protein alpha chain UniProt Synonym Protein Names Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60 Protein Family GA-binding protein UniProt Gene Name GABPA [Similar Products] UniProt Synonym Gene Names E4TF1A; GABP subunit alpha [Similar Products] TOP NCBI Summary for GABPA This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010] TOP UniProt Comments for GABPA GABPA: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. Belongs to the ETS family.Protein type: DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 21q21.3Cellular Component: nuclear chromatin; nucleoplasm; nucleusMolecular Function: DNA binding; protein binding; protein heterodimerization activity; transcription coactivator activity; transcription factor activityBiological Process: cell differentiation; mitochondrion organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter Research Articles on GABPA 1. ELF1 binding occurs at both TERT promoter mutations in melanoma in vitro such that increased recruitment of GABP is enabled by the spatial architecture of native and novel ETS motifs in the TERT promoter region. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-GABPA antibody Reference Product PubMed Publications GABPB1 antibody >25 publications with GABPA and GABPB1 TFAM antibody >12 publications with GABPA and TFAM PPARGC1A antibody >9 publications with GABPA and PPARGC1A NRF1 antibody >7 publications with GABPA and NRF1 TFB1M antibody >4 publications with GABPA and TFB1M PPRC1 antibody >2 publications with GABPA and PPRC1 POLRMT antibody >1 publications with GABPA and POLRMT TFB2M antibody >1 publications with GABPA and TFB2M Pathways associated with anti-GABPA antibody Products by Pathway Pathway Diagram Allograft Rejection Pathway antibodies Allograft Rejection Pathway Diagram Hematopoietic Stem Cell Gene Regulation By GABP Alpha/beta Complex Pathway antibodies Hematopoietic Stem Cell Gene Regulation By GABP Alpha/beta Complex Pathway Diagram Mitochondrial Gene Expression Pathway antibodies Mitochondrial Gene Expression Pathway Diagram Mitochondrial Biogenesis Pathway antibodies Mitochondrial Biogenesis Pathway Diagram Myometrial Relaxation And Contraction Pathways antibodies Myometrial Relaxation And Contraction Pathways Diagram Organelle Biogenesis And Maintenance Pathway antibodies Organelle Biogenesis And Maintenance Pathway Diagram Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram Diseases associated with anti-GABPA antibody Disease Name Pubmed Publications Disease Models, Animal Antibodies >18 publications with GABPA and Disease Models, Animal Cardiovascular Diseases Antibodies >11 publications with GABPA and Cardiovascular Diseases Inflammation Antibodies >10 publications with GABPA and Inflammation Liver Diseases Antibodies >7 publications with GABPA and Liver Diseases Necrosis Antibodies >6 publications with GABPA and Necrosis Fatty Liver Antibodies >5 publications with GABPA and Fatty Liver Neurobehavioral Manifestations Antibodies >4 publications with GABPA and Neurobehavioral Manifestations Neoplasms, Experimental Antibodies >4 publications with GABPA and Neoplasms, Experimental Liver Neoplasms Antibodies >3 publications with GABPA and Liver Neoplasms Breast Neoplasms Antibodies >3 publications with GABPA and Breast Neoplasms Organs/Tissues associated with anti-GABPA antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >25 publications with GABPA and Blood Liver Antibodies >22 publications with GABPA and Liver Brain Antibodies >21 publications with GABPA and Brain Muscle Antibodies >18 publications with GABPA and Muscle Heart Antibodies >7 publications with GABPA and Heart Lung Antibodies >5 publications with GABPA and Lung Testis Antibodies >4 publications with GABPA and Testis Intestine Antibodies >3 publications with GABPA and Intestine Embryonic Tissue Antibodies >3 publications with GABPA and Embryonic Tissue Connective Tissue Antibodies >3 publications with GABPA and Connective Tissue TOP © 2006-24 MyBioSource.com. 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