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anti-GABPA antibody :: Mouse anti-Human, Mouse GABPA Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9602559
Western Blot (WB)
Unit / Price
0.05 mL  /  $235 +1 FREE 8GB USB
0.1 mL  /  $295 +1 FREE 8GB USB
0.2 mL  /  $370 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GABPA, Monoclonal Antibody

★Popular Item★
 Also Known As   

GABPA Antibody

 Product Synonym Names    E4TF 1A; E4TF1 60; E4TF1A; GA binding protein alpha chain; GA binding protein transcription factor alpha subunit 60kDa; GA binding protein transcription factor alpha subunit; GA-binding protein alpha chain; GABP A; GABP alpha subunit; GABP subunit alpha; Gabpa; GABPA_HUMAN; Human nuclear respiratory factor 2 subunit alpha; NFT 2; NFT2; NRF 2; NRF 2A; NRF2; NRF2A; Nuclear respiratory factor 2 alpha subunit; Nuclear respiratory factor 2 subunit alpha; RCH04A07; Transcription factor E4TF1 60; Transcription factor E4TF1-60
 Product Gene Name   

anti-GABPA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q06546
 Clonality    Monoclonal
 Isotype    IgG1
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Specificity    GABPA antibody detects endogenous levels of total GABPA
 Purity/Purification    Affinity-Chromatography
 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    Purified recombinant fragment of human GABPA expressed in E. Coli
 Subcellular Location    Nucleus.
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-GABPA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GABPA antibody

   Description: GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Function: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.
Subunit Structure: Heterotetramer of two alpha and two beta subunits.
Similarity: Belongs to the ETS family.
 Applications Tested/Suitable for anti-GABPA antibody   

Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)

 Application Notes for anti-GABPA antibody    ELISA: 1:10000
WB: 1:500-1:2000
ICC: 1:200-1:1000
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 Western Blot (WB) of anti-GABPA antibody    Figure 1: Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF-7 (3), NIH/3T3 (4) and SMMC-7721 (5) cell lysate.
anti-GABPA antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GABPA. It may not necessarily be applicable to this product.
 NCBI GI #    308818209
 NCBI GeneID    2551
 NCBI Accession #    NP_001184226.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001197297.1 [Other Products]
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 UniProt Primary Accession #    Q06546 [Other Products]
 UniProt Secondary Accession #    Q12939 [Other Products]
 UniProt Related Accession #    Q06546 [Other Products]
 Molecular Weight    Observed: 51 kDa
Predicted: 52 kDa
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 NCBI Official Full Name    GA-binding protein alpha chain
 NCBI Official Synonym Full Names    GA binding protein transcription factor subunit alpha
 NCBI Official Symbol    GABPA [Similar Products]
 NCBI Official Synonym Symbols   
NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07
[Similar Products]
 NCBI Protein Information    GA-binding protein alpha chain
 UniProt Protein Name    GA-binding protein alpha chain
 UniProt Synonym Protein Names   
Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60
 Protein Family    GA-binding protein
 UniProt Gene Name    GABPA [Similar Products]
 UniProt Synonym Gene Names    E4TF1A; GABP subunit alpha [Similar Products]
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 NCBI Summary for GABPA    This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]
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 UniProt Comments for GABPA    Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.
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 Research Articles on GABPA    1. Data indicate the essential role of the GABP transcription factor in activating translocase of inner mitochondrial membrane 23 TIMM23 and TIMM23B expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GABPA antibodyPathways associated with anti-GABPA antibody
 Reference Product  PubMed Publications
 GABPB1 antibody  >21 publications with GABPA and GABPB1
 TFAM antibody  >12 publications with GABPA and TFAM
 SP1 antibody  >8 publications with GABPA and SP1
 KEAP1 antibody  >3 publications with GABPA and KEAP1
 Products by Pathway  Pathway Diagram
 Energy Metabolism Pathway antibodies  Energy Metabolism Pathway Diagram
 Mitochondrial Biogenesis Pathway antibodies  Mitochondrial Biogenesis Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies  Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram
Diseases associated with anti-GABPA antibodyOrgans/Tissues associated with anti-GABPA antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >12 publications with GABPA and Nervous System Diseases
 Disease Models, Animal Antibodies  >10 publications with GABPA and Disease Models, Animal
 Inflammation Antibodies  >8 publications with GABPA and Inflammation
 Cardiovascular Diseases Antibodies  >6 publications with GABPA and Cardiovascular Diseases
 Necrosis Antibodies  >6 publications with GABPA and Necrosis
 Liver Diseases Antibodies  >4 publications with GABPA and Liver Diseases
 Fatty Liver Antibodies  >3 publications with GABPA and Fatty Liver
 Neurobehavioral Manifestations Antibodies  >3 publications with GABPA and Neurobehavioral Manifestations
 Hypertension Antibodies  >2 publications with GABPA and Hypertension
 Liver Cirrhosis Antibodies  >2 publications with GABPA and Liver Cirrhosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >20 publications with GABPA and Blood
 Liver Antibodies  >17 publications with GABPA and Liver
 Muscle Antibodies  >15 publications with GABPA and Muscle
 Brain Antibodies  >15 publications with GABPA and Brain
 Heart Antibodies  >6 publications with GABPA and Heart
 Lung Antibodies  >5 publications with GABPA and Lung
 Testis Antibodies  >4 publications with GABPA and Testis
 Embryonic Tissue Antibodies  >3 publications with GABPA and Embryonic Tissue
 Connective Tissue Antibodies  >3 publications with GABPA and Connective Tissue
 Thyroid Antibodies  >2 publications with GABPA and Thyroid
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