Q1ZYL6
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UniProt Related Accession #
NCBI Official Full Name
granulocyte colony-stimulating factor receptor
NCBI Official Synonym Full Names
colony stimulating factor 3 receptor (granulocyte)
NCBI Official Synonym Symbols
NCBI Protein Information
granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 antigen; G-CSF receptor; OTTHUMP00000009703; OTTHUMP00000009704; OTTHUMP00000009705
UniProt Protein Name
Granulocyte colony-stimulating factor receptor
UniProt Entry Name
Q1ZYL6_HUMAN
NCBI Summary for CSF3R
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq]
UniProt Comments for CSF3R
GCSFR: the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variant isoforms have been described.
Protein type: Membrane protein, integral; Receptor, cytokine
Chromosomal Location of Human Ortholog: 1p35-p34.3
Cellular Component: integral to plasma membrane; extracellular region
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity
Biological Process: neutrophil chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; cell adhesion; signal transduction
Disease: Neutrophilia, Hereditary
Research Articles on CSF3R
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Products associated with anti-CSF3R antibody
Pathways associated with anti-CSF3R antibody
Diseases associated with anti-CSF3R antibody
Organs/Tissues associated with anti-CSF3R antibody
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