NP_004855.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,140 Da
NCBI Official Full Name
growth/differentiation factor 15
NCBI Official Synonym Full Names
growth differentiation factor 15
NCBI Official Synonym Symbols
PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15 [Similar Products]
NCBI Protein Information
growth/differentiation factor 15; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; prostate differentiation factor; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
UniProt Protein Name
Growth/differentiation factor 15
UniProt Synonym Protein Names
Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor
UniProt Synonym Gene Names
UniProt Entry Name
GDF15_HUMAN
NCBI Summary for GDF-15
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]
UniProt Comments for GDF-15
Subunit structure: Homodimer; disulfide-linked
By similarity.
Subcellular location: Secreted
Probable.
Tissue specificity: Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
Sequence similarities: Belongs to the TGF-beta family.
Research Articles on GDF-15
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Products associated with anti-GDF-15 antibody
Pathways associated with anti-GDF-15 antibody
Diseases associated with anti-GDF-15 antibody
Organs/Tissues associated with anti-GDF-15 antibody
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